Cytogenetic investigations on patients with difficulties in reproducing; [LES RECHERCHES CYTOGENETIQUES CHEZ LES SUJETS AYANT DES ECHECS DE LA REPRODUCTION]

Abstract

Our cytogenetic investigations have been carried out on 200 people with difficulties in reproduction consisting of 30 couples who were sterile and 70 couples who had spontaneous abortions. The results that we have obtained showed the following chromosome abnormalities: trisomy XXY, translocation of type 13:14, pericentric inversions of chromosome 9, translocation X:9 (q24:q34) and deletion of chromosome X (delq 23). In this series of patients we have obtained the following chromosome variations: 9qh+, Yq- and Yq+, 14s+ and 21s+. The causal role of these abnormalities and chromosome variations on the failure of reproduction is discussed.