Publication: Melanoma tumor inhibition by tetrachlorido(O,O′-dibutyl- ethylenediamine-N,N′-di-3-propionate)platinum(iv) complex: In vitro and in vivo investigations
| dc.contributor.author | Maksimović-Ivanić, Danijela (6507584634) | |
| dc.contributor.author | Mijatović, Sanja (6508347659) | |
| dc.contributor.author | Mirkov, Ivana (23973384600) | |
| dc.contributor.author | Stošić-Grujičić, Stanislava (7004253020) | |
| dc.contributor.author | Miljković, Djordje (7006524033) | |
| dc.contributor.author | Sabo, Tibor J. (7004201321) | |
| dc.contributor.author | Trajković, Vladimir (7004516866) | |
| dc.contributor.author | Kaluerović, Goran N. (7801430570) | |
| dc.date.accessioned | 2025-06-12T22:13:53Z | |
| dc.date.available | 2025-06-12T22:13:53Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | Tetrachlorido(O,O′-dibutyl-ethylenediamine-N,N′-di-3- propionate)platinum(iv) complex, [PtCl4(n-Bu2eddp)], was previously found to be effective against fibrosarcoma and glioma cell lines. Here we presented that [PtCl4(n-Bu2eddp)] strongly reduced the growth of B16 melanoma cells in vitro. Inhibition of cell viability was accompanied with induction of both necrotic and apoptotic cell death. In addition, [PtCl4(n-Bu2eddp)] concealed the expansion of tumors induced in syngeneic C57Bl/6 mice without visible signs of nephrotoxicity. © The Royal Society of Chemistry 2012. | |
| dc.identifier.uri | https://doi.org/10.1039/c2mt20150j | |
| dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84867870472&doi=10.1039%2fc2mt20150j&partnerID=40&md5=1709355129f84460b906f9dda61b02ee | |
| dc.identifier.uri | https://remedy.med.bg.ac.rs/handle/123456789/9783 | |
| dc.title | Melanoma tumor inhibition by tetrachlorido(O,O′-dibutyl- ethylenediamine-N,N′-di-3-propionate)platinum(iv) complex: In vitro and in vivo investigations | |
| dspace.entity.type | Publication |