Publication:
Neuropsychiatric aspects of treated Wilson's disease

dc.contributor.authorSvetel, Marina (6701477867)
dc.contributor.authorPotrebić, Aleksandra (6507575592)
dc.contributor.authorPekmezović, Tanja (7003989932)
dc.contributor.authorTomić, Aleksandra (26654535200)
dc.contributor.authorKresojević, Nikola (26644117100)
dc.contributor.authorJešić, Rada (6701488512)
dc.contributor.authorDragašević, Nataša (59157743200)
dc.contributor.authorKostić, Vladimir S. (35239923400)
dc.date.accessioned2025-07-02T12:46:04Z
dc.date.available2025-07-02T12:46:04Z
dc.date.issued2009
dc.description.abstractThe objective of the current cross-sectional study was to use standardized psychiatric interviews (the Structured Clinical Interview for DSM-IV Axis I Disorders and the Neuropsychiatric Inventory; NPI) in order to better characterize psychiatric symptoms in 50 consecutive, treated and clinically stable patients with Wilson's disease (WD). Nine patients (18%) had one, 7 patients (14%) had two, and 20 (40%) had ≥ 3 neuropsychiatric symptoms present. The most often endosed symptoms were anxiety (62%), depression (36%), irritability (26%), as well as disinhibition and apathy (24% each). Twenty two patients (44%) had a score ≥ 4 on at least one of the NPI items: again, most frequently anxiety (17 patients; 34%), depression (13 patients; 26%) and apathy (9 patients; 18%). Therefore, even among stable, long-term treated patients with WD approximately 70% experienced psychiatric symptoms. © 2009 Elsevier Ltd. All rights reserved.
dc.identifier.urihttps://doi.org/10.1016/j.parkreldis.2009.01.010
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-70450253340&doi=10.1016%2fj.parkreldis.2009.01.010&partnerID=40&md5=812880dd4a268822271933137b3dcfe8
dc.identifier.urihttps://remedy.med.bg.ac.rs/handle/123456789/14190
dc.subjectNeuropsychiatric inventory
dc.subjectPsychiatric symptoms
dc.subjectWilson's disease
dc.titleNeuropsychiatric aspects of treated Wilson's disease
dspace.entity.typePublication

Files