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Regulation of immune response to SRBC: Suppressor cell activity by soluble fraction of antigen

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dc.contributor.authorLukic, M.L. (7005792112)
dc.contributor.authorJanezic, A. (6701711147)
dc.contributor.authorPopeskovic, L. (6602953096)
dc.date.accessioned2025-07-02T13:02:35Z
dc.date.available2025-07-02T13:02:35Z
dc.date.issued1978
dc.description.abstractWater soluble fraction (SF) of SRBC was obtained by hypotonic lysis and ultracentrifugation. SF was found to induce very weak SRBC-specific antibody response in mice. Pretreatment with SF accelerated direct PFC response to SRBC and accelerated and suppressed indirect PFC response. Spleen cells from mice treated with SF exhibited enhanced response to SRBC after transfer in irradiated recipients. The transfer of spleen cells from mice treated with SF to normal non-irradiated mice markedly suppressed the recipients' PFC responses to SRBC. The observed suppressive effect is interpreted as a consequence of suppressor cell activity.
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-0017881596&partnerID=40&md5=5f5e85e04b9b19a11cfeee172e09b007
dc.identifier.urihttps://remedy.med.bg.ac.rs/handle/123456789/14800
dc.titleRegulation of immune response to SRBC: Suppressor cell activity by soluble fraction of antigen
dspace.entity.typePublication

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