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Immunomodulatory action of mycobacterial secretory proteins

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dc.contributor.authorTrajkovic, Vladimir (7004516866)
dc.contributor.authorNatarajan, Krishnamurthy (7101659388)
dc.contributor.authorSharma, Pawan (7403232336)
dc.date.accessioned2025-06-13T00:40:27Z
dc.date.available2025-06-13T00:40:27Z
dc.date.issued2004
dc.description.abstractThe recently discovered RD1 locus encodes proteins that are actively secreted by pathogenic mycobacteria, including Mycobacterium tuberculosis. Since they are missing in non-tuberculous mycobacteria, these proteins are promising not only as candidates for vaccination and diagnostic tests, but also in understanding mycobacterial evasion of protective immunity in susceptible individuals. Here we analyze the possible role of M. tuberculosis secretory proteins in immunity against tuberculosis, with emphasis on their immunomodulatory action and the potential involvement in mycobacterial subversion of the host immune defense. © 2004 Elsevier SAS. All rights reserved.
dc.identifier.urihttps://doi.org/10.1016/j.micinf.2003.12.015
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-1942517331&doi=10.1016%2fj.micinf.2003.12.015&partnerID=40&md5=849b70494cb397ef7571a2ea032ffbef
dc.identifier.urihttps://remedy.med.bg.ac.rs/handle/123456789/11187
dc.subject10-kDa culture filtrate protein
dc.subject6-kDa early secretory antigenic target
dc.subjectCFP-10
dc.subjectDC
dc.subjectDendritic cell
dc.subjectESAT-6
dc.subjectImmunity
dc.subjectImmunomodulation
dc.subjectInducible nitric oxide synthase
dc.subjectINOS
dc.subjectMast cell
dc.subjectMC
dc.subjectMtb
dc.subjectMycobacterium tuberculosis
dc.subjectTuberculosis
dc.titleImmunomodulatory action of mycobacterial secretory proteins
dspace.entity.typePublication

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