Publication: Concomitant drug-and infection-induced antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis with multispecific ANCA
| dc.contributor.author | Kontic, Milica (43761339600) | |
| dc.contributor.author | Radovanovic, Sanja (56432618100) | |
| dc.contributor.author | Nikolic, Milos (56910382000) | |
| dc.contributor.author | Bonaci-Nikolic, Branka (10839652200) | |
| dc.date.accessioned | 2025-06-12T21:57:34Z | |
| dc.date.available | 2025-06-12T21:57:34Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | Objective: To report the first case of concomitant drug-and infection-induced antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) in a patient treated with propylthiouracil (PTU) and suffering from tuberculosis. Presentation and Intervention: A 28-year-old woman with PTU-treated hyperthyroidism presented with fever, purpura, pulmonary cavitations and ANCA to myeloperoxidase, bactericidal/permeability-increasing protein (BPI), proteinase-3 and elastase. Skin histopathology confirmed vasculitis. However, sputum examination revealed Mycobacterium tuberculosis. Remission was achieved after PTU withdrawal and treatment with antituberculosis drugs. Conclusion: Our case confirmed that BPI-ANCA are elevated in active tuberculosis. Multispecific ANCA were helpful for the diagnosis of concomitant PTU-and M. tuberculosis-induced AAV. Copyright © 2012 S. Karger AG, Basel. | |
| dc.identifier.uri | https://doi.org/10.1159/000337944 | |
| dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84865009842&doi=10.1159%2f000337944&partnerID=40&md5=611885312211ce00a717907646a2d91e | |
| dc.identifier.uri | https://remedy.med.bg.ac.rs/handle/123456789/9620 | |
| dc.subject | Antineutrophil cytoplasmic autoantibodies | |
| dc.subject | Bactericidal/permeability-increasing protein | |
| dc.subject | Drug-induced vasculitis | |
| dc.subject | Propylthiouracil | |
| dc.subject | Tuberculosis | |
| dc.title | Concomitant drug-and infection-induced antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis with multispecific ANCA | |
| dspace.entity.type | Publication |