Significance of 99m Tc-MIBI scintigraphy as preoperative diagnostic method in parathyroid gland disorders: Case report

Abstract

The aim of our study is to show significance of 99m Tb- methoxyisobutyl-isonitril (MIBI) scintigraphy as a localization diagnostic preoperative method in surgical treatment of the parathyroid gland (PT) disorders. We showed in this study a patient who had surgical interventions twice due to primary hyperparathyreoidism (PHPT) caused by hyperplasia of the parathyroid glands and carcinoma of the ectopic parathyroid gland. The first surgical intervention was performed without preoperative diagnostics with 99m Tc-MIBI scintigraphy. In the second surgical intervention 99m Tc-MIBI scintigraphy was done preoperatively and it clearly showed a tumor change in the posterior mediastinum that corresponded to the ectopic parathyroid gland (PT). Pathohistologic (PH) findings after the surgical extirpation of PT showed that there was carcinoma of the ectopic PT By using 99m Tc-MIBI scintigraphy as a localization method before the first surgical intervention, the patient could be spared from undergoing the second surgical intervention and all operative and postoperative risks that these operations had.