Paget's disease of the vulva - A review of our experience

Abstract

Objective: The aim of our study was to review our experience with Paget's disease of the vulvar relative to initial examination, treatment and oncological outcome. Methods: Ten women with extramammary Paget's diseases of the vulva were treated during the 10-year period. The charts of these patients were reviewed and data were collected regarding patient demographics, symptoms, previous Paget's disease, surgical treatments and time to recurrence. Results: Eight women (80%) were treated with wide local excision or partial vulvectomy, and two patients (20%) required radical resection for invasive adenocarcinoma. The group of women who had invasive diseases also underwent inquinofemoral lymphadenectomy and no lymphatic métastases were noted. Three women (30%) experienced recurrence. The mean time to relapse was 30 months (range 3-88 months). Conclusion: Recurrence is very common and long-term monitoring is recommended with careful examination of any abnormal vulvar lesion.