Publication:
Guanidinoacetic acid versus creatine for improved brain and muscle creatine levels: A superiority pilot trial in healthy men

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dc.contributor.authorOstojic, Sergej M. (8552029600)
dc.contributor.authorOstojic, Jelena (12797904900)
dc.contributor.authorDrid, Patrik (57209794562)
dc.contributor.authorVranes, Milan (16246559800)
dc.date.accessioned2025-06-12T18:57:17Z
dc.date.available2025-06-12T18:57:17Z
dc.date.issued2016
dc.description.abstractIn this randomized, double-blind, crossover trial, we evaluated whether 4-week supplementation with guanidinoacetic acid (GAA) is superior to creatine in facilitating creatine levels in healthy men (n = 5). GAA (3.0 g/day) resulted in a more powerful rise (up to 16.2%) in tissue creatine levels in vastus medialis muscle, middle-cerebellar peduncle, and paracentral grey matter, as compared with creatine (P < 0.05). These results indicate that GAA as a preferred alternative to creatine for improved bioenergetics in energy-demanding tissues. © 2016, Canadian Science Publishing. All right reserved.
dc.identifier.urihttps://doi.org/10.1139/apnm-2016-0178
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84985898275&doi=10.1139%2fapnm-2016-0178&partnerID=40&md5=23d4bdbba7880540675417309ddfccc5
dc.identifier.urihttps://remedy.med.bg.ac.rs/handle/123456789/7867
dc.subjectBioenergetics
dc.subjectCerebellum
dc.subjectHomocysteine
dc.subjectVastus medialis muscle
dc.titleGuanidinoacetic acid versus creatine for improved brain and muscle creatine levels: A superiority pilot trial in healthy men
dspace.entity.typePublication

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