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Children and adolescents with marginal zone lymphoma have an excellent prognosis with limited chemotherapy or a watch-and-wait strategy after complete resection

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dc.contributor.authorRonceray, Leila (54911933000)
dc.contributor.authorAbla, Oussama (6506167666)
dc.contributor.authorBarzilai-Birenboim, Shlomit (57192254129)
dc.contributor.authorBomken, Simon (24401060100)
dc.contributor.authorChiang, Alan K. S. (7101623534)
dc.contributor.authorJazbec, Janez (6602993382)
dc.contributor.authorKabickova, Edita (6602305248)
dc.contributor.authorLazic, Jelena (7004184322)
dc.contributor.authorBeishuizen, Auke (7003615260)
dc.contributor.authorMellgren, Karin (6602767529)
dc.contributor.authorTanaka, Fumiko (57205773592)
dc.contributor.authorPillon, Marta (7006404245)
dc.contributor.authorDevalck, Christine (6701501578)
dc.contributor.authorGouttenoire, Marina (57195222083)
dc.contributor.authorMakarova, Olga (57212714301)
dc.contributor.authorBurkhardt, Birgit (9248143700)
dc.contributor.authorAttarbaschi, Andishe (6602343033)
dc.date.accessioned2025-06-12T16:33:09Z
dc.date.available2025-06-12T16:33:09Z
dc.date.issued2018
dc.description.abstractData on management of pediatric marginal zone lymphoma (MZL) are scarce. This retrospective study assessed characteristics and outcome in 66 patients who were <18 years old. Forty-four (67%) had an extranodal MZL (EMZL), 21 (32%) a nodal MZL (NMZL), and one patient a splenic MZL. Thirty-three patients (50%) received a variable combination of adjuvant chemotherapy/immunotherapy/radiotherapy, while the remainder, including 20 of 21 with NMZL, entered an active observation period. Overall survival was excellent (98 ± 2%), although 11 patients relapsed (17%; NMZL, n = 1; EMZL, n = 10), seven after any therapy and four after complete resection only. In conclusion, outcome of NZML, in particular, seems to be excellent after (in)complete resection and observation only. © 2017 Wiley Periodicals, Inc.
dc.identifier.urihttps://doi.org/10.1002/pbc.26932
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85039761187&doi=10.1002%2fpbc.26932&partnerID=40&md5=09d806f987a61a0538e3d3bed01867e4
dc.identifier.urihttps://remedy.med.bg.ac.rs/handle/123456789/6425
dc.subjectcomplete resection
dc.subjectmarginal zone lymphoma
dc.subjectoutcome
dc.subjectwatch-and-wait
dc.titleChildren and adolescents with marginal zone lymphoma have an excellent prognosis with limited chemotherapy or a watch-and-wait strategy after complete resection
dspace.entity.typePublication

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