Publication: Management of drug hypersensitivity in the pediatric population
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Date
2016
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Abstract
Introduction: Several recent studies confirmed that drug allergy in children is over diagnosed, which is a major public health problem, and results in use of alternative drugs, increasing resistance and health costs. Areas covered: Articles in English with data on drug hypersensitivity in children were identified by searching the databases of MEDLINE (National Library of Medicine) from 1990 till 2016. Expert commentary: It is crucial to make a precise diagnosis with performing a complete allergy work-up based on carefully selected diagnostic tests depending on whether an immediate or a non-immediate reaction is suspected. The drug provocation test remains the gold standard in diagnostic drug hypersensitivity in children. © 2016 Informa UK Limited, trading as Taylor & Francis Group.
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Keywords
Allergy, children, drug hypersensitivity, drug provocation tests, immediate reactions, non-immediate reactions, non-steroidal anti-inflammatory drugs, non-β-lactam antibiotics, skin tests, β-lactam antibiotics