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RibosomeLamella complexes in the peripheral blood of patients with chronic lymphocytic leukemia are associated with serological immune deficiency

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dc.contributor.authorKravic-Stevovic, Tamara (35275295500)
dc.contributor.authorBogdanovic, Andrija (6603686934)
dc.contributor.authorBoskovic, Darinka (7004419750)
dc.contributor.authorBumbasirevic, Vladimir (6603957757)
dc.date.accessioned2025-06-12T23:17:24Z
dc.date.available2025-06-12T23:17:24Z
dc.date.issued2010
dc.description.abstractThe ribosomelamella complex (RLC) is a cylindrical structure composed of different numbers of circular lamellae with associated particles, regarded as ribosomes, around a central core. Structures resembling RLC, but lacking the typical mature appearance of RLC, have been called pre-RLC. The authors have found RLCs and pre-RLCs in peripheral lymphocytes of 3 patients with chronic lymphocytic leukemia (CLL). The fact that CLL patients with RLCs were in early Rai clinical stages, had good clinical prognostic factors, and did not require immediate therapy indicates that RLCs occurred in the early course of some cases of CLL. Moreover, the presence of RLC was associated with hypogammaglobulinemia M. © 2010 Informa UK Ltd.
dc.identifier.urihttps://doi.org/10.3109/01913120903419492
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-75149186627&doi=10.3109%2f01913120903419492&partnerID=40&md5=630e43062825888340ba9b4eff2200e3
dc.identifier.urihttps://remedy.med.bg.ac.rs/handle/123456789/10404
dc.subjectCLL
dc.subjectHypogammablobulinemia
dc.subjectIntracytoplasmic inclusions
dc.subjectPeripheral lymphocytes
dc.subjectRibosome-lamella complex
dc.subjectUltrastructure
dc.titleRibosomeLamella complexes in the peripheral blood of patients with chronic lymphocytic leukemia are associated with serological immune deficiency
dspace.entity.typePublication

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