Acute hemodynamic effects of metoprolol ± nitroglycerin in patients with biopsy-proven lymphocytic myocarditis

Abstract

We evaluated acute hemodynamic effects of metoprolol ± nitroglycerin in 11 patients with left ventricular dysfunction and biopsy-proven lymphocyte myocarditis. Acute administration of metoprolol improved ejection phase indexes, probably through the prolongation of diastole; the addition of a vasodilator further enhanced these effects by improving arterial elastance.