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Clinical effects of topical pimecrolimus in a patient with Fox-Fordyce disease

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dc.contributor.authorMilcic, Danijela (55218170900)
dc.contributor.authorNikolic, Milos (56910382000)
dc.date.accessioned2025-06-12T22:10:23Z
dc.date.available2025-06-12T22:10:23Z
dc.date.issued2012
dc.description.abstractFox-Fordyce disease (FFD) is characterized by a pruritic eruption of skin-coloured or yellowish papules in areas rich in apocrine glands. The histology comprises dilatation of follicular infundibula with hyperkeratosis, acanthosis, and spongiosis of the infundibular epithelium with perifollicular infiltration of lymphocytes and foamy histiocytes. We treated a 12-year-old girl with FFD with topical pimecrolimus for 12 weeks, this resulted in a complete clearance of lesions. After the therapy, the patient was followed for an additional 19 months without signs of relapse. The effects of pimecrolimus in FFD might imply that an inflammatory process inducing secondary reactive hyperkeratosis could be involved in the pathogenesis of FFD. © 2010 The Australasian College of Dermatologists.
dc.identifier.urihttps://doi.org/10.1111/j.1440-0960.2010.00711.x
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84861056181&doi=10.1111%2fj.1440-0960.2010.00711.x&partnerID=40&md5=981505971d0cc4d76ab7dff92254739e
dc.identifier.urihttps://remedy.med.bg.ac.rs/handle/123456789/9749
dc.subjectFox-Fordyce disease
dc.subjectpimecrolimus
dc.subjecttherapy
dc.titleClinical effects of topical pimecrolimus in a patient with Fox-Fordyce disease
dspace.entity.typePublication

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