Browsing by Author "Zivkovic, Snezana (36718938200)"

Purpose; Cancer is the one of the leading cause of death worldwide. The aim of this study was to examine cancer mortality trends in the population of central Serbia in the period from 2002 to 2011. Methods; The descriptive epidemiological method was used. The mortality from all malignant tumors (code C00-C96 of the International Disease Classification) was registered. The source of mortality data was the published material of the Cancer Registry of Serbia. The source of population data was the census of 2002 and 2011 and the estimates for inter-census years. Non-standardized, age-ad-justed and age-specific mortality rates were calculated. Age adjustment of mortality rates was performed by the direct method of standardization. Trend lines were estimated using linear regression. Results: During 2002-2011, cancer caused about 20% of all deaths each year in central Serbia. More men (56.9%) than women (43.1%) died of cancer. The average mortality rate for men was 1.3 times higher compared to women. A significant trend of increase of the age-adjusted mortality rates was recorded both for males (p<0.001 ) and for females (p=0.02). Except gastric cancer, the age-adjusted mortality rates in men were significantly increased for lung cancer (p=0.002), colorectal cancer (p<0.05), prostate cancer (p=0.001) and pancreatic cancer (p=0.001). Age-adjusted mortality rates for breast cancer infernales were remarkably increased (p=0.001), especially after 2007. Conclusions: In central Serbia during the period from 2002 to 2011, there was an increasing trend in mortality rates due to cancers in both sexes. Cancer mortality in males was 1.3-fold higher compared to females.

Purpose; Cancer is the one of the leading cause of death worldwide. The aim of this study was to examine cancer mortality trends in the population of central Serbia in the period from 2002 to 2011. Methods; The descriptive epidemiological method was used. The mortality from all malignant tumors (code C00-C96 of the International Disease Classification) was registered. The source of mortality data was the published material of the Cancer Registry of Serbia. The source of population data was the census of 2002 and 2011 and the estimates for inter-census years. Non-standardized, age-ad-justed and age-specific mortality rates were calculated. Age adjustment of mortality rates was performed by the direct method of standardization. Trend lines were estimated using linear regression. Results: During 2002-2011, cancer caused about 20% of all deaths each year in central Serbia. More men (56.9%) than women (43.1%) died of cancer. The average mortality rate for men was 1.3 times higher compared to women. A significant trend of increase of the age-adjusted mortality rates was recorded both for males (p<0.001 ) and for females (p=0.02). Except gastric cancer, the age-adjusted mortality rates in men were significantly increased for lung cancer (p=0.002), colorectal cancer (p<0.05), prostate cancer (p=0.001) and pancreatic cancer (p=0.001). Age-adjusted mortality rates for breast cancer infernales were remarkably increased (p=0.001), especially after 2007. Conclusions: In central Serbia during the period from 2002 to 2011, there was an increasing trend in mortality rates due to cancers in both sexes. Cancer mortality in males was 1.3-fold higher compared to females.

Purpose: The aim of this study was to analyze trends of death rates for cervical cancer (CC) on territory of The Re-public of Serbia in the period 1991-2011. Methods: In this descriptive epidemiological study, unpublished data of the Statistical Office of the Republic of Serbia were used for the analysis of mortality due to CC among women in Serbia, from 1991 to 2Oil. Three different types of rates were calculated: crude, age-specific and age-adjusted rates. The age-standardized rates were calculated by the direct method of standardization using the World Standard Population as standard. The trends were assessed by joinpoint linear regression analysis. An average annual percentage change (AAPC) and the corresponding 95% confidence intervals (CI) were computed for screening programs has dramatically reduced the mortality rates of CC [3]. Based on the information presented by the International Agency for Research on Cancer (IARC) in 2012, Serbia is in the third place for the mortality, after Romania and Moldova [4]. According to unpublished data of the Cancer Registry of the Institute of Public Health of Serbia "Dr Milan Jovanovic Batut", in 2011, the CC standardized mortality rate was 6.9 per 100,000 women [5]. With contribution of 5.5% in central trends. Results: The average age-standardized CC mortality rate (ASCCMR) was 7.03 per 100,000. The lowest value of the ASCCMR was at the beginning of the observed period (6.05 per 100,000) and the highest was 8.17 per 100,000 in 2008. The age-adjusted CC mortality rates have been continuously and significantly increasing (AAPC=+0.7, 95% CI=0.3- 1.1, p<0.05). In all age groups we found increasing trends, except in the age group of 65-74 years. Conclusion: Since ASCCMR has been steadily increasing during the period observed, reducing these rates is highly warranted. To achieve this target, an organized CC screening program is essential.

Purpose: The aim of this study was to analyze trends of death rates for cervical cancer (CC) on territory of The Re-public of Serbia in the period 1991-2011. Methods: In this descriptive epidemiological study, unpublished data of the Statistical Office of the Republic of Serbia were used for the analysis of mortality due to CC among women in Serbia, from 1991 to 2Oil. Three different types of rates were calculated: crude, age-specific and age-adjusted rates. The age-standardized rates were calculated by the direct method of standardization using the World Standard Population as standard. The trends were assessed by joinpoint linear regression analysis. An average annual percentage change (AAPC) and the corresponding 95% confidence intervals (CI) were computed for screening programs has dramatically reduced the mortality rates of CC [3]. Based on the information presented by the International Agency for Research on Cancer (IARC) in 2012, Serbia is in the third place for the mortality, after Romania and Moldova [4]. According to unpublished data of the Cancer Registry of the Institute of Public Health of Serbia "Dr Milan Jovanovic Batut", in 2011, the CC standardized mortality rate was 6.9 per 100,000 women [5]. With contribution of 5.5% in central trends. Results: The average age-standardized CC mortality rate (ASCCMR) was 7.03 per 100,000. The lowest value of the ASCCMR was at the beginning of the observed period (6.05 per 100,000) and the highest was 8.17 per 100,000 in 2008. The age-adjusted CC mortality rates have been continuously and significantly increasing (AAPC=+0.7, 95% CI=0.3- 1.1, p<0.05). In all age groups we found increasing trends, except in the age group of 65-74 years. Conclusion: Since ASCCMR has been steadily increasing during the period observed, reducing these rates is highly warranted. To achieve this target, an organized CC screening program is essential.

Objective: To examine cancer mortality trends in Central Serbia (1985-2002). Methods: Cancer mortality rates were based on the official death certificates (n=192849). They were standardized for age and sex. Results: In the observed period, mortality rates showed a tendency to increase in both males (y=118.54+2.27x, p=0.0001) and females (y=83.32+1.02x,p=0.0001). Mortality of lung cancer increased in both sexes (y=32.38+0.86x, p < 0.001 for males, y=6.25+0.25 y<0.001 for females), as did colorectal cancer (y=10.87+033x, p<0.001 for males, y=8.51+0.09x, p < 0.05 for females). Breast cancer mortality rates increased (y = 14.48+0.35x, p=0.0001), and so did cervical cancer (y = 5.14+0.14x, p<0.01). Mortality of gastric cancer in males has been moderately decreasing after 1990s (y (1990-2002) =13.67-0.20x, p<0.01), while prostate cancer mortality remained relatively stable. Conclusions: Increasing cancer mortality trends in the last 18 years in Central Serbia indicate the extremely urgent needs for health authorities to adopt measures of cancer prevention that proved effective in other countries. © Birkhäuser Verlag, Basel 2006.