Browsing by Author "Zelić, Ksenija (36633421800)"

Introduction/Objective Finite element analysis (FEA) is mathematical method which can be used for the assessment of biomechanical behavior of dento-alveolar complex. The objectives were to analyze biomechanical behavior changes of teeth and supporting tissues under occlusal load in cases of horizontal and vertical alveolar bone loss, to assess potential impact of tooth displacement and altered stress distribution on further damage, and to evaluate the impact of regenerative periodontal therapy. Methods Three patient-specific three-dimensional finite element (3D FE) models were developed from the acquired cone beam computed tomography, comprising the patient’s upper left canine, first and second premolar, and adjacent bone. Model 1 represented horizontal bone loss. Model 2 included intrabony defect along distal aspect of tooth #24. Model 3 represented situation six months after the regenerative periodontal surgery. Displacement, Von Mises, and principal stresses were evaluated through FEA, under moderate vertical occlusal load. Results FEA demonstrated that in the model with vertical bone loss significant tooth displacement was present, even though the clinically evident tooth mobility was absent. Biomechanical behavior and stress distribution of teeth and surrounding tissues under moderate occlusal load was much more altered in case with vertical bone loss in comparison with horizontal bone loss. Six months following the regenerative therapy, the values of all evaluated parameters were noticeable reduced. Conclusion Regenerative periodontal therapy improved the biomechanical characteristics of the affected teeth and the related periodontal structures. © 2021, Serbia Medical Society. All rights reserved.

Introduction Pathogenesis and some characteristics of periodontitis cannot be fully explained by bacterial etiology alone. Herpes viruses may bridge the gap between clinical characteristics and molecular understanding of periodontal destruction. Objective The aim of this study was to investigate the prevalence of herpes simplex virus type 1 (HSV-1) in gingival crevicular fluid (GCF) of healthy and damaged periodontium in Serbian population and to explore potential correlation between the presence of this virus and the level of periodontal destruction. Methods Samples were collected from gingival sulcus/periodontal pockets by sterile paper points and the presence of viral DNA in gingival crevicular fluid was assessed by PCR. Results There was no statistically significant difference in HSV-1 in presence between periodontitis patients (PG=38.9%) and healthy controls (HC=32.3%), (Chi-square test, with Yates' correction p=0.7574). However, HSV-1 positive patients showed significantly higher values of parameters of periodontal destruction (PPD=7.11 ±2.52, CAL=5.46±2.34) than periodontitis patients without HSV-1 in gingival crevicular fluid (PPD=4.70±1.79, CAL=3.39±2.65) (p values respectively, p=0.002 and p=0.023, Independent Samples T-Test). HSV-1 occurred more often in deeper (PPD>6 mm) (69.2%) than in shallow pockets (3 mm

Introduction/Objective The class II malocclusion results in disbalanced facial harmony, primarily notice-able in the profile and the lower facial third. Aside from skeletal evaluation, orthodontic diagnosis and treatment planning should include facial soft tissue analysis. The aim of the study was to identify the soft tissue profile outcomes of orthodontic treatment of class II, division 1 malocclusion patients and to determine if these changes are related to different treatment protocols. Methods The first group was the non-extraction group (25 patients) initially treated with the Herbst appli-ance, and the second group was four premolars extraction group (25 patients) treated with a multibracket appliance. The patients’ cephalograms and pre-and post-treatment profile photographs were used. Results The improvement in the non-extraction group was evident in the decrease of the nasomental angle, the angle representing the projection of the upper lip to the chin, as well as the upper lip angle. In the extraction group, the nasolabial angle showed a significant increase. Soft tissue variables showed significant differences between the groups: the total facial angle or facial convexity including the nose and the angle presenting the projection of the upper lip to the chin. Conclusion The patients treated without extractions showed a significant improvement of the convex profile and favorable soft tissue changes in the lower third of the face. © 2022, Serbia Medical Society. All rights reserved.

Introduction/Objective The aim of the study was to test the accuracy of Belgrade Age Formula (BAF) for dental age estimation on the sample of Montenegrin children. Methods The radiographs of 134 Montenegrin children (67 females and 67 males) saved as “jpeg” files were analyzed with Image J software. Sex, the number of teeth with complete development, apex width and tooth length of the mandibular canine and second molar were used in order to calculate dental age with the BAF formula. Results The discrepancy between estimated dental age and chronological age was-0.088 ± 0.64 years; the absolute difference was 0.52 ± 0.39 years. The percentage of participants whose estimated dental age differed six months from their chronological age was 61.2 and 53.7 for females and males, respec-tively, while the percentage of participants whose estimated dental age differed 12 months from their chronological age was 94 and 83.6 for females and males, respectively. Conclusion The BAF may be an accurate approach for estimating dental age in Montenegrin children aged 10–12 years with uncompleted tooth development. However, BAF has to be evaluated on a larger sample of Montenegrin infants in future studies. © 2022, Serbia Medical Society. All rights reserved.

Identification of living undocumented individuals highlights the need for accurate, precise, and reproducible age estimation methods, especially in those cases involving minors. However, when their country of origin is unknown, or it can be only roughly estimated, it is extremely difficult to apply assessment policies, procedures, and practices that are accurate and child-sensitive. The main aim of this research is to optimize the correct classification of adults and minors by establishing new cut-off values for four different continents (Africa, America, Asia, and Europe). For this purpose, a vast sample of 10,701 orthopantomographs (OPTs) from four continents was evaluated. For determination and subsequent validation of the new third molar maturity index (I3M) cut-off values by world regions, a cross-validation by holdout method was used and contingency tables (confusion matrices) were generated. The lower third molar maturity indexes, from both left and right side (I3ML and I3MR) and the combination of both sides (I3ML_I3MR) were calculated. The new cut-off values, that aim to differentiate between a minor and an adult, with more than 74.00% accuracy for all populations were as follows (I3ML; I3MR; I3ML_I3MR, respectively): Africa = (0.10; 0.10; 0.10), America = (0.10; 0.09; 0.09), Asia = (0.15; 0.17; 0.14), and Europe = (0.09; 0.09; 0.09). The higher sensitivity (Se) was detected for the I3ML for male African people (91%) and the higher specificity (Sp) of all the parameters (I3ML; I3MR; I3ML_I3MR) for Europeans both male and female (> 91%). The original cut-off value (0.08) is still useful, especially in discriminating individuals younger than 18 years old which is the goal of the forensic methods used for justice. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.