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Browsing by Author "Zdravkovic, Djordje (57219193639)"

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    Publication
    Influence of Three Different Surgical Techniques on Microscopic Damage of Saphenous Vein Grafts—A Randomized Study
    (2023)
    Zivkovic, Igor (57192104502)
    ;
    Krasic, Stasa (57192096021)
    ;
    Stankovic, Milica (58117716900)
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    Milacic, Petar (24832086700)
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    Milutinovic, Aleksandar (57205247589)
    ;
    Zdravkovic, Djordje (57219193639)
    ;
    Tabakovic, Zoran (57898013700)
    ;
    Peric, Miodrag (7006618529)
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    Krstic, Miljan (23485491100)
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    Bojic, Milovan (7005865489)
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    Milic, Dragan (35877861700)
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    Micovic, Slobodan (25929461500)
    Background and Objectives: The saphenous vein is one of the most common used grafts (SVG) for surgical revascularization. The mechanism of the SVGs occlusion is still unknown. Surgical preparation techniques have an important role in the early and late graft occlusion. Our study analyzed the influence of the three different surgical techniques on the histological and immunohistochemical characteristics of the vein grafts. Methods: Between June 2019 and December 2020, 83 patients who underwent surgical revascularization were prospectively randomly assigned to one of the three groups, according to saphenous vein graft harvesting (conventional (CVH), no-touch (NT) and endoscopic (EVH)) technique. The vein graft samples were sent on the histological (hematoxylin-eosin staining) and immunohistochemical (CD31, Factor VIII, Caveolin and eNOS) examinations. Results: The CVH, NT, and EVH groups included 27 patients (mean age 67.66 ± 5.6), 31 patients (mean age 66.5 ± 7.4) and 25 patients (mean age 66 ± 5.5), respectively. Hematoxylin-eosin staining revealed a lower grade of microstructural vein damage in the NT group (2, IQR 1-2) in comparison with CVH and EVH (3, IQR 2-4), (4, IQR 2-4) respectively (p < 0.001). Immunohistochemical examination revealed a high grade of staining in the NT group compared to the CVH and EVH group (CD 31 antibody p = 0.02, FVIII, p < 0.001, Caveolin, p = 0.001, and eNOS, p = 0.003). Conclusion: The best preservation of the structural vein integrity was in the NT group, while the lowest rate of leg wound complication was in the EVH group. These facts increase the interest in developing and implementing the endoscopic no-touch technique. © 2023 by the authors.
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    Publication
    Surgical Reconstruction of a Left Ventricular Aneurysm Using an Extracellular Matrix Patch
    (2022)
    Zivkovic, Igor (57192104502)
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    Mihajlovic, Vladimir (57223157667)
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    Zdravkovic, Djordje (57219193639)
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    Krstic, Djordje (57671162800)
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    Krasic, Srasa (57192096021)
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    Lesanovic, Jelena (57223151871)
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    Peric, Miodrag (7006618529)
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    Milacic, Petar (24832086700)
    The left ventricular aneurysm is a pathological condition defined as an akinetic or dyskinetic area of the left ventricle (LV) wall associated with reduced ejection fraction. The most common surgical technique to reconstruct a left ventricular aneurysm is endoventricular patch plasty (Dor procedure). In this case, endoventricular reconstruction of the left ventricular aneurysm using a double-layer extracellular matrix was performed. © 2022, Sociedade Brasileira de Cirurgia Cardiovascular. All rights reserved.
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    Publication
    Surgical Removal of The Mechanical Valve Leaflet Dislocated into The Pulmonary Vein
    (2022)
    Zdravkovic, Djordje (57219193639)
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    Zivkovic, Igor (57192104502)
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    Kovacevic, Vladimir (36093028200)
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    Milacic, Petar (24832086700)
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    Milicic, Miroslav (22934854000)
    Accidental detachment of mechanical valve leaflet during implantation is a rare and potentially serious complication. When the lost leaflet cannot be found by direct visualisation, additional diagnostic procedures are necessary to detect it. Computer tomography is the best detection method, but the patient needs reoperation. We presented a patient in whom the detached leaflet migrated and became trapped into the left inferior pulmonary vein. The computed tomography (CT) scan was used to reveal leaflets, and successful extirpation was performed in the second operation. © 2022, Sociedade Brasileira de Cirurgia Cardiovascular. All rights reserved.

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