Browsing by Author "Savic, Milan M. (24830640100)"

Introduction: Acute eosinophilic pneumonia (AEP) is idiopathic disease characterized by acute febrile illness, progressive respiratory failure, diffuse pulmonary infiltrates, and pulmonary eosinophilia. The aetiology of AEP is unknown, although several studies have proposed that cigarette smoke is potentially related to the onset of AEP. Herein is a report of a rare case showing the causal association between short-term period of excessive smoking and AEP Case report: A 25-year-old patient was admitted to the ICU (during on-duty hours) as an emergency case due to acute disease occurred a day prior to hospitalisation. His symptoms were febricity, dry cough, excessive fatigue and general weakness. The patient was a non-smoker who had smoked 30 cigarettes a day prior to the onset of the symptoms. At the time of admission, he was voluntary, but somnolent, orientated, febrile, dyspneic, cyanotic, adynamic, and without peripheral lymphadenopathy. Due to both poor oxygenation and the life-threatening condition, the corticosteroid therapy, in addition to the antibiotic therapy were immediately administered to the patient. The eosinophilia was diagnosed based on control tests, such as Le 22.0x10 9, with dominating eosinophilic leucocytes of 12.59 (0-7% reference value) and neutrophils of 86.26 (44-72% reference range), Se 58mm/h, CRP 115, fibrinogen 6.5, while other parametres ranged within the reference scales. Afterwards, eosinophil chamber count of 2300 was found (<350mm 3 reference value). The specific protein value amounted to IgE 255.0 IU/ml (0-100 reference value). The MSCT of the thorax revealed: pneumonic infiltrates of sub-segment type, including associated pleural thickening, observed in the subhilar and bibasal parts, both sides. Moreover, pleural effusion was observed in a minor incisure on the right and in the upper part of a major incisure on the left. Conclusion: The majority of reported cigarette smoking-induced AEP cases are young adults who were first-time smokers. In light of such reports and considering the increase of early cigarette smoking in young adults, it is important that physicians are aware of the possibility of this potentially life-threatening, but fully reversible disease.