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Browsing by Author "Sade, Leyla Elif (12808884600)"

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    Imaging in patients with cardiovascular implantable electronic devices: part 1—imaging before and during device implantation. A clinical consensus statement of the European Association of Cardiovascular Imaging (EACVI) and the European Heart Rhythm Association (EHRA) of the ESC
    (2024)
    Stankovic, Ivan (57197589922)
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    Voigt, Jens-Uwe (35582937800)
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    Burri, Haran (6603663244)
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    Muraru, Denisa (57203383206)
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    Sade, Leyla Elif (12808884600)
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    Haugaa, Kristina Hermann (24733615600)
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    Lumens, Joost (23980665500)
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    Biffi, Mauro (7007143244)
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    Dacher, Jean-Nicolas (54790540100)
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    Marsan, Nina Ajmone (23035780700)
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    Bakelants, Elise (57193525332)
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    Manisty, Charlotte (6504025861)
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    Dweck, Marc R. (12783691400)
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    Smiseth, Otto A. (7006367337)
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    Donal, Erwan (7003337454)
    More than 500 000 cardiovascular implantable electronic devices (CIEDs) are implanted in the European Society of Cardiology countries each year. The role of cardiovascular imaging in patients being considered for CIED is distinctly different from imaging in CIED recipients. In the former group, imaging can help identify specific or potentially reversible causes of heart block, the underlying tissue characteristics associated with malignant arrhythmias, and the mechanical consequences of conduction delays and can also aid challenging lead placements. On the other hand, cardiovascular imaging is required in CIED recipients for standard indications and to assess the response to device implantation, to diagnose immediate and delayed complications after implantation, and to guide device optimization. The present clinical consensus statement (Part 1) from the European Association of Cardiovascular Imaging, in collaboration with the European Heart Rhythm Association, provides comprehensive, up-to-date, and evidence-based guidance to cardiologists, cardiac imagers, and pacing specialists regarding the use of imaging in patients undergoing implantation of conventional pacemakers, cardioverter defibrillators, and resynchronization therapy devices. The document summarizes the existing evidence regarding the use of imaging in patient selection and during the implantation procedure and also underlines gaps in evidence in the field. The role of imaging after CIED implantation is discussed in the second document (Part 2). © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved.
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    Imaging in patients with cardiovascular implantable electronic devices: part 2—imaging after device implantation. A clinical consensus statement of the European Association of Cardiovascular Imaging (EACVI) and the European Heart Rhythm Association (EHRA) of the ESC
    (2024)
    Stankovic, Ivan (57197589922)
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    Voigt, Jens-Uwe (35582937800)
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    Burri, Haran (6603663244)
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    Muraru, Denisa (57203383206)
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    Sade, Leyla Elif (12808884600)
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    Haugaa, Kristina Hermann (24733615600)
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    Lumens, Joost (23980665500)
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    Biffi, Mauro (7007143244)
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    Dacher, Jean-Nicolas (54790540100)
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    Marsan, Nina Ajmone (23035780700)
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    Bakelants, Elise (57193525332)
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    Manisty, Charlotte (6504025861)
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    Dweck, Marc R. (12783691400)
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    Smiseth, Otto A. (7006367337)
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    Donal, Erwan (7003337454)
    Cardiac implantable electronic devices (CIEDs) improve quality of life and prolong survival, but there are additional considerations for cardiovascular imaging after implantation—both for standard indications and for diagnosing and guiding management of device-related complications. This clinical consensus statement (part 2) from the European Association of Cardiovascular Imaging, in collaboration with the European Heart Rhythm Association, provides comprehensive, up-to-date, and evidence-based guidance to cardiologists, cardiac imagers, and pacing specialists regarding the use of imaging in patients after implantation of conventional pacemakers, cardioverter defibrillators, and cardiac resynchronization therapy (CRT) devices. The document summarizes the existing evidence regarding the role and optimal use of various cardiac imaging modalities in patients with suspected CIED-related complications and also discusses CRT optimization, the safety of magnetic resonance imaging in CIED carriers, and describes the role of chest radiography in assessing CIED type, position, and complications. The role of imaging before and during CIED implantation is discussed in a companion document (part 1). © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved.
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    Inter-center reproducibility of standard and advanced echocardiographic parameters in the EACVI-AFib echo registry
    (2023)
    Santoro, Ciro (54795845800)
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    Donal, Erwan (7003337454)
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    Magne, Julien (22938314200)
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    Sade, Leyla Elif (12808884600)
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    Penicka, Martin (12773733600)
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    Katbeh, Asim (57204961268)
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    Cosyns, Bernard (57202595662)
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    Cameli, Matteo (36906722500)
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    Hanzevacki, Jadranka Separovic (6504689300)
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    Luksic, Vlatka Reskovic (57192309548)
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    Agricola, Eustachio (7004352036)
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    Citro, Rodolfo (15921921800)
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    Hagendorff, Andreas (7004833586)
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    Lancellotti, Patrizio (7003380556)
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    Habib, Gilbert (7101933258)
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    Moreo, Antonella (36807886900)
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    Cardim, Nuno (7004229183)
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    Parato, Vito Maurizio (6507131553)
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    Neskovic, Alexsandar (35597744900)
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    Rosca, Monica (54891777000)
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    Galli, Elena (57198206282)
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    Motoc, Andreea (57203957863)
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    Mandoli, Giulia (57008235300)
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    Ingallina, Giacomo (55324936100)
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    Prota, Costantina (55635036000)
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    Stoebe, Stephen (55515325600)
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    Piette, Caroline (57200423353)
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    Mouhat, Basile (57195725462)
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    Carbone, Andreina (55253376900)
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    Chiara, Benedetta De (36129416100)
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    Ilardi, Federica (41561578200)
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    Stankovic, Ivan (57197589922)
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    Zamorano, Jose Luis (7101735283)
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    Popescu, Bogdan Alexandru (37005664700)
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    Edvardsen, Thor (6603263370)
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    Galderisi, Maurizio (57203882101)
    Aim: we sought to test the inter-center reproducibility of 16 echo laboratories involved in the EACVI-Afib Echo Europe. Methods: This was done on a dedicated setting of 10 patients with sinus rhythm (SR) and 10 with persistent atrial fibrillation (AF), collected by the Principal Investigator. Images and loops of echo-exams were stored and made available for labs. The tested measurements included main echo-Doppler parameters, global longitudinal strain (GLS) and peak atrial longitudinal strain (PALS). Results: Single measures interclass correlation coefficients (ICCs) of left ventricular mass and ejection fraction were suboptimal in both patients with SR and AF. Among diastolic parameters, ICCs of deceleration time were poor, in particular in AF (=.50). ICCs of left atrial size and function, besides optimal in AF, showed an acceptable despite moderate concordance in SR. ICC of GLS was.81 and.78 in SR and AF respectively. ICCs of PALS were suitable but lower in 4-chamber than in 2-chamber view. By depicting the boxplot of the 16 laboratories, GLS distribution was completely homogeneous in SR, whereas GLS of AF and PALS of both SR and AF presented a limited number of outliers. GLS mean ± SE of the 16 labs was 19.7 ±.36 (95% CI: 18.8-20.4) in SR and 16.5 ±.29 (95% CI: 15.9-17.1) in AF, whereas PALS mean ± SE was 43.8 ±.70 (95% CI: 42.3-45.3) and 10.2 ±.32 (95% CI: 9.5-10.9) respectively. Conclusion: While the utilization of some standard-echo variables should be discouraged in registries, the application of GLS and PALS could be largely promoted because their superior reproducibility, even in AF. © 2023 The Authors. Echocardiography published by Wiley Periodicals LLC.
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    Multimodality imaging in patients with heart failure and preserved ejection fraction: An expert consensus document of the European Association of Cardiovascular Imaging
    (2022)
    Smiseth, Otto A. (7006367337)
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    Morris, Daniel A. (37056154300)
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    Cardim, Nuno (7004229183)
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    Cikes, Maja (55895105900)
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    Delgado, Victoria (24172709900)
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    Donal, Erwan (7003337454)
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    Flachskampf, Frank A (7006759790)
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    Galderisi, Maurizio (57203882101)
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    Gerber, Bernhard L (7102014010)
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    Gimelli, Alessia (6603051677)
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    Klein, Allan L (7402142693)
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    Knuuti, Juhani (57210225163)
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    Lancellotti, Patrizio (7003380556)
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    Mascherbauer, Julia (6507613914)
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    Milicic, Davor (56503365500)
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    Seferovic, Petar (6603594879)
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    Solomon, Scott (7401460954)
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    Edvardsen, Thor (6603263370)
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    Popescu, Bogdan A. (37005664700)
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    Bertrand, Philippe B. (55754216700)
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    Dweck, Marc (12783691400)
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    Haugaa, Kristina H. (24733615600)
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    Sade, Leyla Elif (12808884600)
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    Stankovic, Ivan (58102398200)
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    Ha, Jong-Won (57965523300)
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    Nagueh, Sherif (7006967559)
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    Oh, Jae K (7402155034)
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    Ohte, Nobuyuki (55630495700)
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    Cosyns, Bernard (57202595662)
    Nearly half of all patients with heart failure (HF) have a normal left ventricular (LV) ejection fraction (EF) and the condition is termed heart failure with preserved ejection fraction (HFpEF). It is assumed that in these patients HF is due primarily to LV diastolic dysfunction. The prognosis in HFpEF is almost as severe as in HF with reduced EF (HFrEF). In contrast to HFrEF where drugs and devices are proven to reduce mortality, in HFpEF there has been limited therapy available with documented effects on prognosis. This may reflect that HFpEF encompasses a wide range of different pathological processes, which multimodality imaging is well placed to differentiate. Progress in developing therapies for HFpEF has been hampered by a lack of uniform diagnostic criteria. The present expert consensus document from the European Association of Cardiovascular Imaging (EACVI) provides recommendations regarding how to determine elevated LV filling pressure in the setting of suspected HFpEF and how to use multimodality imaging to determine specific aetiologies in patients with HFpEF. © 2021 Published on behalf of the European Society of Cardiology. All rights reserved.
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    Rationale and design of the EACVI AFib Echo Europe Registry for assessing relationships of echocardiographic parameters with clinical thrombo-embolic and bleeding risk profile in non-valvular atrial fibrillation
    (2018)
    Galderisi, Maurizio (7005866296)
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    Donal, Erwan (7003337454)
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    Magne, Julien (22938314200)
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    Lo Iudice, Francesco (57218922523)
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    Agricola, Eustachio (7004352036)
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    Sade, Leyla Elif (12808884600)
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    Cameli, Matteo (36906722500)
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    Schwammenthal, Ehud (7007108816)
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    Cardim, Nuno (7004229183)
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    Cosyns, Bernard (57202595662)
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    Hagendorff, Andreas (7004833586)
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    Neskovic, Alexandar N. (35597744900)
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    Zamorano, Josè Luis (7101735283)
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    Lancellotti, Patrizio (7003380556)
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    Habib, Gilbert (7101933258)
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    Edvardsen, Thor (6603263370)
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    Popescu, Bogdan A. (37005664700)
    The European Society of Cardiology (ESC) guidelines for management of atrial fibrillation (AF) recommend the use of CHA 2 DS 2 VASc risk score for assessment of thromboembolic (TE) risk, whereas the stratification of bleeding risk should be obtained by HAS-Bleed to balance the most appropriate anticoagulation (OAC) therapy. However, men with CHA 2 DS 2 VASc score = 1 and women with CHA 2 DS 2 VASc = 2, who are at intermediate TE risk, represent a grey zone where guidelines do not provide a definite OAC indication. Accordingly, implementation of risk stratification with echocardiography could be extremely useful. Both prospective and cross-sectional studies on transthoracic echocardiography (TTE) prediction of TE events and studies utilizing transoesophageal echocardiographic parameters as surrogate markers of TE events makes sustainable the hypothesis that echocardiography could improve TE prediction in non-valvular AF. Moreover, considering the close association of AF and stroke, all echo-Doppler parameters that have shown to predict AF onset and recurrence could be useful also to predict TE events in this clinical setting. Accordingly, EACVI AFib Echo Europe Registry has been designed as an observational, cross-sectional study, with the aim of evaluating: (i) left atrial (LA) size and function together with left ventricular geometry, systolic and diastolic functions in paroxysmal, persistent, and permanent AF; (ii) relationships of structural/functional parameters with clinical TE and bleeding risk profile. By the AFib Echo Europe Registry, we expect to collect data on echocardiographic phenotype of patients with AF. The large data set accumulated will be useful to test the level of agreement of different echocardiographic measurements with the available risk scores. © 2017 The Author.
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    The clinical use of stress echocardiography in chronic coronary syndromes and beyond coronary artery disease: A clinical consensus statement from the European Association of Cardiovascular Imaging of the ESC
    (2024)
    Picano, Eugenio (7102408994)
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    Pierard, Luc (57214710368)
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    Peteiro, Jesus (7003845482)
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    Djordjevic-Dikic, Ana (57003143600)
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    Sade, Leyla Elif (12808884600)
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    Cortigiani, Lauro (55663049600)
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    Van De Heyning, Caroline M (12797752300)
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    Celutkiene, Jelena (6507133552)
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    Gaibazzi, Nicola (6603190525)
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    Ciampi, Quirino (6602299243)
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    Senior, Roxy (55165129300)
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    Neskovic, Aleksandar N (35597744900)
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    Henein, Michael (7006300845)
    Since the 2009 publication of the stress echocardiography expert consensus of the European Association of Echocardiography, and after the 2016 advice of the American Society of Echocardiography-European Association of Cardiovascular Imaging for applications beyond coronary artery disease, new information has become available regarding stress echo. Until recently, the assessment of regional wall motion abnormality was the only universally practiced step of stress echo. In the state-of-the-art ABCDE protocol, regional wall motion abnormality remains the main step A, but at the same time, regional perfusion using ultrasound-contrast agents may be assessed. Diastolic function and pulmonary B-lines are assessed in step B; left ventricular contractile and preload reserve with volumetric echocardiography in step C; Doppler-based coronary flow velocity reserve in the left anterior descending coronary artery in step D; and ECG-based heart rate reserve in non-imaging step E. These five biomarkers converge, conceptually and methodologically, in the ABCDE protocol allowing comprehensive risk stratification of the vulnerable patient with chronic coronary syndromes. The present document summarizes current practice guidelines recommendations and training requirements and harmonizes the clinical guidelines of the European Society of Cardiology in many diverse cardiac conditions, from chronic coronary syndromes to valvular heart disease. The continuous refinement of imaging technology and the diffusion of ultrasound-contrast agents improve image quality, feasibility, and reader accuracy in assessing wall motion and perfusion, left ventricular volumes, and coronary flow velocity. Carotid imaging detects pre-obstructive atherosclerosis and improves risk prediction similarly to coronary atherosclerosis. The revolutionary impact of artificial intelligence on echocardiographic image acquisition and analysis makes stress echo more operator-independent and objective. Stress echo has unique features of low cost, versatility, and universal availability. It does not need ionizing radiation exposure and has near-zero carbon dioxide emissions. Stress echo is a convenient and sustainable choice for functional testing within and beyond coronary artery disease. © 2023 The Author(s). Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved.
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    The role of multi-modality imaging for the assessment of left atrium and left atrial appendage: a clinical consensus statement of the European Association of Cardiovascular Imaging (EACVI), European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC)
    (2025)
    Sade, Leyla Elif (12808884600)
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    Faletra, Francesco Fluvio (56147841200)
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    Pontone, Gianluca (8342393600)
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    Gerber, Bernhard Lothar Marie (7102014010)
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    Muraru, Denisa (57203383206)
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    Edvardsen, Thor (6603263370)
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    Cosyns, Bernard (57202595662)
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    Popescu, Bogdan (37005664700)
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    Klein, Allan (7402142693)
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    Marwick, Thomas (7102424966)
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    Cameli, Matteo (36906722500)
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    Saric, Muhamed (7005163334)
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    Thomas, Liza (7403526999)
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    Ajmone Marsan, Nina (23035780700)
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    Fontes-Carvalho, Ricardo (23097322300)
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    Podlesnikar, Tomaz (57188636569)
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    Fontana, Marianna (16306839900)
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    La Gerche, Andre (23501677000)
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    Petersen, Steffen Erhard (35430477200)
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    Moharem-Elgamal, Sarah (55511971300)
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    Bittencourt, Marcio Sommer (36117675900)
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    Vannan, Mani (7004765301)
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    Glikson, Michael (7006774407)
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    Peichl, Petr (7004756002)
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    Cochet, Hubert (35108774800)
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    Stankovic, Ivan (57197589922)
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    Donal, Erwan (7003337454)
    Structural, architectural, contractile, or electrophysiological alterations may occur in the left atrium (LA). The concept of LA cardiopathy is supported by accumulating scientific evidence demonstrating that LA remodelling has become a cornerstone diagnostic and prognostic marker. The structure and the function of the LA and left atrial appendage (LAA), which is an integral part of the LA, are key elements for a better understanding of multiple clinical conditions, most notably atrial fibrillation, cardioembolism, heart failure, and mitral valve diseases. Rational use of various imaging modalities is key to obtain the relevant clinical information. Accordingly, this clinical consensus document from the European Association of Cardiovascular Imaging, in collaboration with the European Heart Rhythm Association, provides comprehensive, up-to-date, and evidence-based guidance to cardiologists and cardiac imagers for the best practice of imaging LA and LAA for the diagnosis, management, and prognostication of the patients. © The Author(s) 2025.

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