Browsing by Author "Radovanovic, Aleksandar (59740325100)"

Background: Surgical site infections (SSIs) are common in colorectal surgery, with rates ranging from 5.4% to 30%. This study evaluated the impact of a perioperative prevention bundle on SSI incidence. Methods: A prospective cohort study with a before-after analysis was conducted from April 2022 to April 2023. The intervention included patient education, preoperative and postoperative chlorhexidine bathing, and mandatory glove change before fascial closure. Results: The implementation of the perioperative prevention bundle resulted in a significant reduction in the overall SSI rate, from 18.5% to 3.8% (P = .016). Superficial SSIs were decreased from 11.1% to 0% (P = .012), while reductions in deep and organ-space SSIs were not statistically significant. Additionally, rehospitalization rates within 30 days dropped from 14.0% to 2.0% (P = .029). The intervention achieved full compliance among patients and staff. Discussion: The individualized approach likely contributed to high compliance, potentially enabling patients to take a more active role in their care. Further research is needed to address the challenges associated with deep and organ-space infections. Conclusions: The implementation of a perioperative prevention bundle, emphasizing patient education and engagement, effectively reduced the incidence of SSIs and rehospitalization rates following colorectal surgery. © 2025 Association for Professionals in Infection Control and Epidemiology, Inc.

Backround/Objectives: Colorectal cancer presents a significant quality of life (QoL) challenge as a result of both the disease and its treatments. This study aimed to validate and culturally adapt the Cleveland Clinic Colorectal Cancer Quality of Life Questionnaire (CCF-CaQL) for Serbian-speaking colorectal cancer patients. Methods: The CCF-CaQL offers a detailed assessment of the physical, emotional, social, and functional impacts of the disease. This study, conducted at the University Clinical Center of Serbia, involved 150 colorectal cancer patients undergoing treatment. The translation and adaptation process followed the EORTC Quality of Life Group’s guidelines, ensuring cultural relevance and comprehensibility. Statistical analyses, including Cronbach’s alpha for internal consistency and Pearson’s correlation for concurrent validity, reliability, and known-groups validity, were performed using SPSS and R software. Results: The Serbian version of the CCF-CaQL maintains strong psychometric properties with high internal consistency (Cronbach’s alpha = 0.85) and significant correlations with the FACT-C questionnaire, confirming its validity. Known-groups validity showed distinct variations in QoL scores based on tumor location, stoma presence, and neoadjuvant therapy status, highlighting its sensitivity to different clinical conditions. Conclusions: The CCF-CaQL questionnaire has been skillfully translated, culturally adapted, and carefully validated through psychometric evaluations for Serbian patients diagnosed with colorectal cancer. © 2025 by the authors.

Backround/Objectives: Colorectal cancer presents a significant quality of life (QoL) challenge as a result of both the disease and its treatments. This study aimed to validate and culturally adapt the Cleveland Clinic Colorectal Cancer Quality of Life Questionnaire (CCF-CaQL) for Serbian-speaking colorectal cancer patients. Methods: The CCF-CaQL offers a detailed assessment of the physical, emotional, social, and functional impacts of the disease. This study, conducted at the University Clinical Center of Serbia, involved 150 colorectal cancer patients undergoing treatment. The translation and adaptation process followed the EORTC Quality of Life Group’s guidelines, ensuring cultural relevance and comprehensibility. Statistical analyses, including Cronbach’s alpha for internal consistency and Pearson’s correlation for concurrent validity, reliability, and known-groups validity, were performed using SPSS and R software. Results: The Serbian version of the CCF-CaQL maintains strong psychometric properties with high internal consistency (Cronbach’s alpha = 0.85) and significant correlations with the FACT-C questionnaire, confirming its validity. Known-groups validity showed distinct variations in QoL scores based on tumor location, stoma presence, and neoadjuvant therapy status, highlighting its sensitivity to different clinical conditions. Conclusions: The CCF-CaQL questionnaire has been skillfully translated, culturally adapted, and carefully validated through psychometric evaluations for Serbian patients diagnosed with colorectal cancer. © 2025 by the authors.