Browsing by Author "Radovanović, Z. (7005270902)"

The highest relative risk of developing tumours of the renal pelvis and ureters (TPU) in a general population is confined to areas where Balkan nephropathy (BN) is endemic. Whether there is a higher frequency of cancer of any site in families with TPU cases from this BN endemic part of the world was tested by a case-referent study. A group of 65 rural patients with histologically proven TPU was individually matched with the same number of their nearest neighbours, who served as controls. Comparison of age-standardized ratios revealed that over a period of 30 years family members of the cases experienced a significantly higher risk of (non-urinary) cancer deaths than family members of their pairmates. © 1985 Springer-Verlag.

The highest relative risk of developing tumours of the renal pelvis and ureters (TPU) in a general population is confined to areas where Balkan nephropathy (BN) is endemic. Whether there is a higher frequency of cancer of any site in families with TPU cases from this BN endemic part of the world was tested by a case-referent study. A group of 65 rural patients with histologically proven TPU was individually matched with the same number of their nearest neighbours, who served as controls. Comparison of age-standardized ratios revealed that over a period of 30 years family members of the cases experienced a significantly higher risk of (non-urinary) cancer deaths than family members of their pairmates. © 1985 Springer-Verlag.

By comparison of topographical distribution of endemic nephropathy foci and hydro- geological structure of affected areas, it has been found that very slow velocity of the base flow in the aquifer from which their water supply is derived is the general characteristic of all endemic villages. In one small town surrounded by endemic settlements there is no endemic nephropathy, although the water pumped for its waterworks is derived from the same aquifer which supplies inhabitants of the most known endemic focus. It is suggested that the creation of a cone of depression might prevent occurrence of the disease, possibly by quicker groundwater flow and shorter period of pollution in the well. © 1979 The Society of Community Medicine.

The General Health Questionnaire (GHQ) has been shown to be a valid instrument for the screening of psychological impairment in a group of Yugoslav medical students. However, consecutive testing of the same population revealed a fall in sensitivity to the unacceptably low figure of 64.7%. A high proportion of false negative results related to two facts: misrepresentation by cases when answering the GHQ; and recall bias on the part of the psychiatrist, i. e. his inability to ignore his previous knowledge of the patients when diagnosing their present condition. © 1988 Springer-Verlag.

The General Health Questionnaire (GHQ) has been shown to be a valid instrument for the screening of psychological impairment in a group of Yugoslav medical students. However, consecutive testing of the same population revealed a fall in sensitivity to the unacceptably low figure of 64.7%. A high proportion of false negative results related to two facts: misrepresentation by cases when answering the GHQ; and recall bias on the part of the psychiatrist, i. e. his inability to ignore his previous knowledge of the patients when diagnosing their present condition. © 1988 Springer-Verlag.