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Browsing by Author "Radojevic, Sanja (56581990900)"

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    Primary non-hodgkin lymphoma of urinary bladder with nine years later renal involvement and absence of systemic lymphoma: A case report
    (2008)
    Terzic, Tatjana (55916182400)
    ;
    Radojevic, Sanja (56581990900)
    ;
    Cemerikic-Martinovic, Vesna (6602432953)
    ;
    Stevanovic, Radmila (36875127400)
    ;
    Citlucanin, Sanja (24478374400)
    ;
    Mitrovic, Dragan (7004955837)
    ;
    Stojimirovic, Biljana (7004273397)
    ;
    Markovic-Lipkovski, Jasmina (6603725388)
    Aims: Primary bladder non-Hodgkin lymphoma (PBNHL) is very rare, especially as extranodal B-small lymphocytic lymphoma (B-SLL). Also, late isolated renal manifestation of PBNHL is extremely unusual. We report a very rare type of extranodal B-SLL of bladder wall with extremely unusual late isolated renal involvement, clinically manifested by nephrotic syndrome and incipient renal failure. A case report: A 56-year-old woman was presented with a solitary tumor of bladder wall, with history of dysuria and night sweating. A transvaginal needle biopsy of the tumor was performed, and diagnosis of primary extranodal B-SLL was made in the absence of bone marrow, lymph node, or blood involvement. She was treated with chemotherapy until the achievement of complete remission. Nine years later, she developed nephrotic syndrome. The renal biopsy revealed parenchymal lymphoma's involvement associated with glomerular lesion. Immunohistochemical analysis confirmed the same imunophenotype of lymphoma cells like in bladder wall nine years ago. Restaging procedure showed no evidence of disease elsewhere. Conclusion: To our knowledge, it is the first case of association of very rare primary bladder B-SLL with late isolated renal involvement. © 2007 Humana Press Inc.
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    Primary non-hodgkin lymphoma of urinary bladder with nine years later renal involvement and absence of systemic lymphoma: A case report
    (2008)
    Terzic, Tatjana (55916182400)
    ;
    Radojevic, Sanja (56581990900)
    ;
    Cemerikic-Martinovic, Vesna (6602432953)
    ;
    Stevanovic, Radmila (36875127400)
    ;
    Citlucanin, Sanja (24478374400)
    ;
    Mitrovic, Dragan (7004955837)
    ;
    Stojimirovic, Biljana (7004273397)
    ;
    Markovic-Lipkovski, Jasmina (6603725388)
    Aims: Primary bladder non-Hodgkin lymphoma (PBNHL) is very rare, especially as extranodal B-small lymphocytic lymphoma (B-SLL). Also, late isolated renal manifestation of PBNHL is extremely unusual. We report a very rare type of extranodal B-SLL of bladder wall with extremely unusual late isolated renal involvement, clinically manifested by nephrotic syndrome and incipient renal failure. A case report: A 56-year-old woman was presented with a solitary tumor of bladder wall, with history of dysuria and night sweating. A transvaginal needle biopsy of the tumor was performed, and diagnosis of primary extranodal B-SLL was made in the absence of bone marrow, lymph node, or blood involvement. She was treated with chemotherapy until the achievement of complete remission. Nine years later, she developed nephrotic syndrome. The renal biopsy revealed parenchymal lymphoma's involvement associated with glomerular lesion. Immunohistochemical analysis confirmed the same imunophenotype of lymphoma cells like in bladder wall nine years ago. Restaging procedure showed no evidence of disease elsewhere. Conclusion: To our knowledge, it is the first case of association of very rare primary bladder B-SLL with late isolated renal involvement. © 2007 Humana Press Inc.
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    Sensitivity and specificity of ex vivo dermatoscopy: a case series
    (2018)
    Dobrosavljevic, Danijela (21133925200)
    ;
    Brasanac, Dimitrije (6603393153)
    ;
    Glumac, Sofija (33467624700)
    ;
    Radojevic, Sanja (56581990900)
    ;
    Matija, Lidija (35327404100)
    ;
    Stanisavljevic, Dejana (23566969700)
    Background: Sensitivity and specificity of ex vivo dermatoscopy (EVD) for malignancy detection of skin tumors is unknown. We sought to assess whether the use of EVD could be a useful adjunct to histopathological diagnosis of pigmented skin tumors, including cases where complete clinical information is inadequate or missing. Materials and methods: EVD was performed on 195 excised, formalin-fixed pigmented skin tumors. Results: Of 183 eligible lesions, 104 (56.8%) were melanocytic and 79 (43.2%) nonmelanocytic. Overall, 54 (29.5%) were malignant: 10 melanomas, 39 basal cell carcinomas, and five squamous cell carcinomas. Ex vivo images were devoid of red color. The following colors were seen: light and dark brown, grey, blue, black, and white. All structures typical for pigmented melanocytic and nonmelanocytic lesions were observed. In malignant nonmelanocytic lesions, diagnostic accuracy and sensitivity for malignant/benign decision was not better when combining visual assessment and EVD but diagnostic specificity improved by 3.0%. For melanoma, combined diagnostics improved diagnostic accuracy, sensitivity, and specificity for 9.6, 30.0, and 7.5%, respectively. Conclusion: For dermatopathologists, EVD offers increased specificity for all categories of tumors and increased diagnostic accuracy, sensitivity, and specificity for melanoma. With EVD view, the dermatopathologist can instantly find areas of interest, thus minimizing the possibility for missing a malignant lesion. © 2018 The International Society of Dermatology
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    Tissue kidney injury molecule-1 expression in the prediction of renal function for several years after kidney biopsy
    (2013)
    Ogrizovic, Sanja Simic (55923197400)
    ;
    Bojic, Suzana (55965837500)
    ;
    Basta-Jovanovic, Gordana (6603093303)
    ;
    Radojevic, Sanja (56581990900)
    ;
    Pavlovic, Jelena (57198008443)
    ;
    Stevuljevic, Jelena Kotur (36629424300)
    ;
    Dopsaj, Violeta (6507795892)
    ;
    Naumovic, Radomir (55965061800)
    Objectives. Retrospective study was designed to examine the importance of tissue kidney injury molecule-1 (KIM-1) expression in predicting kidney function in sixty patients (27 males) aged 34.15 ± 12.23 years with different kidney diseases over three years after kidney biopsy. Materials and Methods. Tissue KIM-1 expression was determined immunohistochemically and KIM-1 staining was scored semiquantitatively, as well as tubulointerstitialis (TIN), inflammation, atrophy, and fibrosis. Kidney function (MDRD formula) and proteinuria/day were evaluated at the time of biopsy (GFR0) and 6, 12, 24, and 36 months later. Results. Significantly positive correlations between tissue KIM-1 expression and age (r = 0.313), TIN inflammation (r = 0.456), fibrosis (r = 0.317), and proteinuria at 6 months (r = 0.394) as well as negative correlations with GFR0 (r = ?0.572), GFR6 (r = ?0.442), GFR24 (r = ?0.398), and GFR36 (r = ?0.412) were found. Meanwhile, TIN inflammation was the best predictor of all measured kidney functions during three years, while tissue KIM-1 expression (P = 0.016) was a predictor only at 6 months after biopsy. Conclusion. Tissue KIM-1 expression significantly predicts kidney function solely at 6 months after biopsy, when the effects of immune and nonimmune treatments are the strongest. Copyright © 2013 Peter Kruzliak et al.
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    Publication
    Tissue kidney injury molecule-1 expression in the prediction of renal function for several years after kidney biopsy
    (2013)
    Ogrizovic, Sanja Simic (55923197400)
    ;
    Bojic, Suzana (55965837500)
    ;
    Basta-Jovanovic, Gordana (6603093303)
    ;
    Radojevic, Sanja (56581990900)
    ;
    Pavlovic, Jelena (57198008443)
    ;
    Stevuljevic, Jelena Kotur (36629424300)
    ;
    Dopsaj, Violeta (6507795892)
    ;
    Naumovic, Radomir (55965061800)
    Objectives. Retrospective study was designed to examine the importance of tissue kidney injury molecule-1 (KIM-1) expression in predicting kidney function in sixty patients (27 males) aged 34.15 ± 12.23 years with different kidney diseases over three years after kidney biopsy. Materials and Methods. Tissue KIM-1 expression was determined immunohistochemically and KIM-1 staining was scored semiquantitatively, as well as tubulointerstitialis (TIN), inflammation, atrophy, and fibrosis. Kidney function (MDRD formula) and proteinuria/day were evaluated at the time of biopsy (GFR0) and 6, 12, 24, and 36 months later. Results. Significantly positive correlations between tissue KIM-1 expression and age (r = 0.313), TIN inflammation (r = 0.456), fibrosis (r = 0.317), and proteinuria at 6 months (r = 0.394) as well as negative correlations with GFR0 (r = ?0.572), GFR6 (r = ?0.442), GFR24 (r = ?0.398), and GFR36 (r = ?0.412) were found. Meanwhile, TIN inflammation was the best predictor of all measured kidney functions during three years, while tissue KIM-1 expression (P = 0.016) was a predictor only at 6 months after biopsy. Conclusion. Tissue KIM-1 expression significantly predicts kidney function solely at 6 months after biopsy, when the effects of immune and nonimmune treatments are the strongest. Copyright © 2013 Peter Kruzliak et al.

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