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Browsing by Author "Petronic, Ivana (25121756800)"

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    Correlation of ABO and Rh blood groups with transfusion administration and fever onset after hip surgery in children
    (2012)
    Brdar, Radivoj (15844992800)
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    Petronic, Ivana (25121756800)
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    Nikolic, Dejan (26023650800)
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    Golubovic, Zoran (57203254059)
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    Bukva, Bojan (55516005300)
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    Radlovic, Vladimir (25121643300)
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    Abramovic, Dusan (33067621500)
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    Ducic, Sinisa (22950480700)
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    Colovic, Hristina (12774005700)
    Objective: Aim of our study was to evaluate distribution of ABO and Rh blood type groups in children after hip surgery regarding transfusion administration and fever presence. Methods: Four types of ABO blood groups (A; B; AB; O) and 2 types of Rh blood groups (Rh+; Rh-) were evaluated in group with administered transfusion (tr+) and without given transfusion (tr-); and in group with fever (fev+) and without fever (fev-), in 146 children after hip surgery. Tr+ and fev+ groups were divided into 3 groups (0-24h; 25-48h; 49-72h): for tr+ group (Group 1, Group 2, Group 3), and for fev+ group (Group A, Group B, Group C). Results: AB blood group significantly decreased in Group 1 (χ2= 6.44; p<0.05) and A blood group in Group 3 in tr+ group (χ2= 7.68; p<0.01). O blood group significantly increased in Group 3 in tr+ group (χ2= 9.96; p<0.01). AB blood group significantly decreased in Groups B (χ2= 12.2; p<0.01) and C (χ2= 4.2; p<0.05) in fev+ versus fevgroup. B blood group significantly increased in Group C (χ2= 34.4; p<0.01) in fev+group. Conclusion: Administration of transfusion and fever onset in pediatric patients undergoing surgical correction of the hip is not influenced by the ABO and Rh blood groups system in humans. There is correlation between distribution of ABO blood groups with the time of transfusion administration and fever onset in children after hip surgery.
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    Cross-cultural adaptation and quantitative evaluation of dysfunctional voiding and incontinence scoring system in pediatric Serbian population
    (2019)
    Cirovic, Dragana (25121527800)
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    Petronic, Ivana (25121756800)
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    Stojkovic, Jasna (57200810273)
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    Soldatovic, Ivan (35389846900)
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    Pavicevic, Polina (25121697400)
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    Bizic, Marta (23970012900)
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    Bokan-Mirkovic, Vesna (55123197500)
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    Knezevic, Tatjana (25121459700)
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    Nikolic, Dejan (26023650800)
    Background and objective: Dysfunctional voiding (DV) presents relatively frequent problem in pediatric urologist practice. The necessity for implementation of DV evaluation in the pediatric population is of particular importance, since there is no clear consensus on the clinical assessment of such condition. The aims of our study were to evaluate the test/retest reliability and reproducibility of dysfunctional voiding and incontinence scoring system: Serbian version (DVISSSR) in patients with voiding and incontinence dysfunctions without structural deformities, and to estimate cut-of value for DVISS SR . Methods: The cross-sectional study included 57 children with voiding and incontinence dysfunctions and 30 healthy pediatric controls. For the evaluation of voiding and incontinence dysfunction we used DVISS. The forward-backward method was applied for translation of the DVISS questionnaire from English into Serbian language. Reproducibility was analyzed by Interclass Correlation Coefficient (ICC). Sensitivity and specificity of DVISS SR scores was done by receiver operating curve (ROC) curve. Results: There was a significant difference in DVISS SR score between patients and controls (p < 0.001). For reliability and reproducibility of the questionnaire, there was no significant difference between repeated measurements (p = 0.141), and strong reliability (ICC = 0.957; p < 0.001). Conclusion: We have demonstrated successful translation and validation of the DVISSSR score. Moreover, a reliable scoring system of children with voiding dysfunctions should include evaluations of symptom scoring systems at the multicentric level. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.
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    Degree of genetic homozygosity and distribution of AB0 blood types among patients with spina bifida occulta and spina bifida aperta
    (2010)
    Nikolic, Dejan (26023650800)
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    Cvjeticanin, Suzana (55924655300)
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    Petronic, Ivana (25121756800)
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    Jekic, Biljana (6603561846)
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    Brdar, Radivoj (15844992800)
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    Damnjanovic, Tatjana (13008423100)
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    Bunjevacki, Vera (6506110754)
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    Maksimovic, Nela (36461365500)
    Introduction: Assuming that spina bifida (SB) is a genetically controlled disease, the aim of our study was to evaluate the degree of genetic homozygosity and the distribution of AB0 blood types among patients with SB occulta and SB aperta by the homozygously recessive characteristics (HRC) test. Material and methods: Our study included an analysis of the presence, distribution and individual combination of 15 selected genetically controlled morpho-physiological traits in a sample of 100 patients with SB (SB occulta N = 50 and SB aperta N = 50) and a control group of individuals (N = 100). Results: We found a statistically significant difference between the mean values for genetic homozygosity (SB 4.5 ±0.3; control 3.0 ±0.2, p < 0.001) and also differences in the presence of certain individual combinations of such traits. In 12 (80.0%) of the 15 observed characteristics, recessive homozygosity was expressed to a greater degree among the group of SB patients, while for 9 (60.0%) of the traits this level of difference was statistically significant (Σx2 = 266.3, p < 0.001). There was no difference in average homozygosity of such genetic markers between groups of SB occulta and SB aperta patients, but the type of individual variation in the two studied groups significantly differed. In the group of patients with SB the frequency of 0 blood group was significantly increased while B blood group was significantly decreased. Conclusions: Our results clearly show that there is a populational genetic difference in the degree of genetic homozygosity and variability between the group of patients with SB and individuals without clinical manifestations, indicating a possible genetic component in the aetiopathogenesis of spina bifida. Copyright © 2010 Termedia & Banach.
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    Distribution of affected muscles and degree of neurogenic lesion in patients with spina bifida
    (2011)
    Petronic, Ivana (25121756800)
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    Nikolic, Dejan (26023650800)
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    Cirovic, Dragana (25121527800)
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    Cvjeticanin, Suzana (55924655300)
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    Knezevic, Tatjana (25121459700)
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    Raicevic, Mirjana (8214104800)
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    Brdar, Radivoj (15844992800)
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    Dzamic, Dragana (8325739000)
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    Janic, Nenad (6506571321)
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    Golubovic, Zoran (57203254059)
    Introduction: Patients with spina bifida in the lumbosacral region usually have various degrees of motor and sensory dysfunctions of the lower extremities and anal sphincter. The aim of our study was to evaluate the distribution and differences in frequencies of affected muscles, number of affected muscles and degree of neurogenic lesion between patients with spina bifida occulta (SBO) and spina bifida aperta (SBA). Material and methods: In 100 patients with SB, 6 muscles in the lower limbs were separately analysed. Due to the number of affected muscles, we evaluated 5 groups of patients: with 1 affected muscle, 2 affected muscles, 3 affected muscles, 4 affected muscles and 5 affected muscles. Three degrees of neurogenic lesions were assessed: mild, moderate and severe. Results: The tibialis anterior muscle was most frequently affected in SB patients. The outer anal sphincter was frequently affected in the group of SBA patients. Single muscle affection is frequent in the group of patients with SBO, while in the group of patients with SBA, 4 muscles were significantly frequently affected. The great majority of patients (45.46%) with affected outer anal sphincter (OAS) in the group of SBO were without affection of other muscles, while for the SBA group it was for every third patient. Mild neurogenic lesion was significantly frequent in SBO patients, while severe form was significantly frequent in SBA patients. Conclusions: Patients with SBO usually present with mild to moderate clinical presentation, while multiple root involvement and severe degree of neurogenic lesion is associated more frequently with SBA. Copyright © 2011 Termedia & Banach.
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    Effects of aerobic training on the risk of coronary artery disease by Duke Treadmill Score in type 2 diabetes mellitus and cardiometabolic health; [Effetti dell’allenamento aerobico sul rischio di coronaropatia nel diabete mellito di tipo 2 e sulle condizioni cardiometaboliche secondo il Duke Treadmill Score]
    (2019)
    Trebinjac, Divna (57210580420)
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    Petronic, Ivana (25121756800)
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    Lalic, Nebojsa (13702597500)
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    Cirovic, Dragana (25121527800)
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    Nikolic, Dejan (26023650800)
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    Stojkovic, Jasna (57200810273)
    BACKGROUND: We aimed to investigate the impact of eight-week aerobic exercise training on the risk of coronary heart disease onset by Duke Treadmill Score (DTS), metabolic equivalent of task (MET), and metabolic syndrome parameters, as well as correlation between those parameters in patients with type 2 diabetes mellitus. There is the clinical value of DTS for the risk stratification as well as strong association between DTS and the combined outcomes of cardiac death, nonfatal myocardial infarction, congestive heart failure and revascularization. METHODS: Sixty patients in stable clinical condition and well-regulated diabetic status conducted all phases of the study. Participants performed treadmill exercise testing using standard Bruce protocol before and after study. Rate of perceived exertion (RPE), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting glucose levels (GLU), waist circumference (WC), triglyceride levels (TRI), high-sensitivity C-reactive protein (hs-CRP), probability of 5-year mortality (P5YM), probability of significant coronary heart disease (pCHD), probability of severe coronary disease (sCHD), DTS and METs levels were evaluated before and after study as well as correlation between DTS, METs and other parameters. RESULTS: The average values of DTS of 4.67 obtained before study indicated a moderate risk for CHD, while average values of 5.61 obtained after study indicated a low risk for CHD. Linear regression model stressed that variable DTS is statistically significant predictor, where higher values of DTS leads to the higher score values of METs. There is statistically significant difference in METs (P<0.001), RPE (P<0.001), sCHD (P=0.038), P5YM (P=0.033) values after study. CONCLUSIONS: Our study suggests that eight-week aerobic exercise training could significantly reduce the risk stratification by DTS from the intermediate to the moderate risk group for coronary heart disease in patients with type 2 diabetes mellitus. Lower values of DTS in women obtained in our research should be investigated in the future studies. Additionally, we have shown that increasing in METs will ultimately bring to decreased mortality in participants with diabetes mellitus type 2 and could significantly improve cardio-metabolic health that indicates the enormous potential value of exercise training. © 2019 EDIZIONI MINERVA MEDICA
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    Effects of aerobic training on the risk of coronary artery disease by Duke Treadmill Score in type 2 diabetes mellitus and cardiometabolic health; [Effetti dell’allenamento aerobico sul rischio di coronaropatia nel diabete mellito di tipo 2 e sulle condizioni cardiometaboliche secondo il Duke Treadmill Score]
    (2019)
    Trebinjac, Divna (57210580420)
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    Petronic, Ivana (25121756800)
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    Lalic, Nebojsa (13702597500)
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    Cirovic, Dragana (25121527800)
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    Nikolic, Dejan (26023650800)
    ;
    Stojkovic, Jasna (57200810273)
    BACKGROUND: We aimed to investigate the impact of eight-week aerobic exercise training on the risk of coronary heart disease onset by Duke Treadmill Score (DTS), metabolic equivalent of task (MET), and metabolic syndrome parameters, as well as correlation between those parameters in patients with type 2 diabetes mellitus. There is the clinical value of DTS for the risk stratification as well as strong association between DTS and the combined outcomes of cardiac death, nonfatal myocardial infarction, congestive heart failure and revascularization. METHODS: Sixty patients in stable clinical condition and well-regulated diabetic status conducted all phases of the study. Participants performed treadmill exercise testing using standard Bruce protocol before and after study. Rate of perceived exertion (RPE), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting glucose levels (GLU), waist circumference (WC), triglyceride levels (TRI), high-sensitivity C-reactive protein (hs-CRP), probability of 5-year mortality (P5YM), probability of significant coronary heart disease (pCHD), probability of severe coronary disease (sCHD), DTS and METs levels were evaluated before and after study as well as correlation between DTS, METs and other parameters. RESULTS: The average values of DTS of 4.67 obtained before study indicated a moderate risk for CHD, while average values of 5.61 obtained after study indicated a low risk for CHD. Linear regression model stressed that variable DTS is statistically significant predictor, where higher values of DTS leads to the higher score values of METs. There is statistically significant difference in METs (P<0.001), RPE (P<0.001), sCHD (P=0.038), P5YM (P=0.033) values after study. CONCLUSIONS: Our study suggests that eight-week aerobic exercise training could significantly reduce the risk stratification by DTS from the intermediate to the moderate risk group for coronary heart disease in patients with type 2 diabetes mellitus. Lower values of DTS in women obtained in our research should be investigated in the future studies. Additionally, we have shown that increasing in METs will ultimately bring to decreased mortality in participants with diabetes mellitus type 2 and could significantly improve cardio-metabolic health that indicates the enormous potential value of exercise training. © 2019 EDIZIONI MINERVA MEDICA
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    Efficacy of magnetic resonance urography in detecting crossing renal vessels in children with ureteropelvic junction obstruction
    (2015)
    Pavicevic, Polina K. (25121697400)
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    Saranovic, Djordjije Z. (57190117313)
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    Mandic, Marija J. (57190812924)
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    Vukadinovic, Vbjkan M. (35619008800)
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    Djordjevic, Miroslav L.J. (7102319341)
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    Radojicic, Zoran I. (12768612400)
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    Petronic, Ivana (25121756800)
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    Cirovic, Dragana (25121527800)
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    Nikolic, Dejan (26023650800)
    INTRODUCTION: An aberrant or accessory crossing renal vessel (CV) leading to the lower pole of the kidney is the most common extrinsic cause of uretero pelvic obstruction(UPf) obstruction in a child and young adolescent. There is still controversy regarding there functional significance in obstruction Preoperative identification of such vessels may influence surgical management. OBJECTIVE: First aim is to determine the value of magnetic resonance (MR) urography in detecting crossing vessels children with UPf obstruction,comparing the data with postoperative findings and the second one is to evaluate morphologic and functional parameters in these hydronephrotic kidneys. MATERIALS AND METHODS: Between June 2009 and December 2012 we retrospectively reviewed MR urography records of one hundred and nine children with unilateral hydronephrosis at the University Children's Hospital. 68 (62.4%) were male and 41 (37.6%) were female,median age was 6.5 ± 5.7. Of the total number of patients, 30 (27%) underwent pyeloplasty, while 79 (72.5%) did not. The age at surgery ranged from 0.3 to 18 years (median 6.6 years). The indication for surgery was based on standard criteria (obstructed renal transit time with or without altered renal function of vDRF < 40%), and did not depend on the presence or absence of a crossing vessel. Consensus reviewes of the urography studies were compared with surgical findings. RESULTS: A crossing vessel (CV) was found upon surgery in 9 (33%) of 30 kidneys.On MRU, there was no crossing vessel in 21 kidneys, confirmed at surgery in 18. A crossing vessel was detected with MRU in 9 kidneys and confirmed at surgery in 6. Thus, the sensitivity of MRU was 66.7%, the specificity was 85.7%, the positive predictive value was 66.7%, the negative predictive value was 85-7% and the accuracy was 80%. There was no statistically significant difference in the detection of crossing vessels between MR urography and surgery (p = 0.004 and p < 0.01 respectively). Overall, MRU and surgery showed good agreement (K = 0.524). CONCLUSION: Based on our results we suggest that MR urography is a reliable and safe diagnostic tool to determine crossing vessels in selected children with UPJ obstruction. Thus, MRU can substitute for other imaging modalities and provide detailed information about the morphology and function of the affected kidney.
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    Estimation of functional recovery in patients after hip fracture by Berg Balance Scale regarding the sex, age and comorbidity of participants
    (2013)
    Radosavljevic, Natasa (55245822900)
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    Nikolic, Dejan (26023650800)
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    Lazovic, Milica (23497397400)
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    Petronic, Ivana (25121756800)
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    Milicevic, Vera (55292831900)
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    Radosavljevic, Zoran (56107375600)
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    Potic, Jelena (55293803000)
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    Ilic-Stojanovic, Olivera (24401526100)
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    Jeremic, Aleksandar (6701360652)
    Aim: To evaluate the functional status measured by Berg Balance Scale (BBS) in elderly aged more than 65years after hip fractures, and to evaluate the influence of sex, age and comorbidity on balance function improvement. Methods: The study included 203 patients with hip fractures. Functional status was evaluated by BBS: at admission (Group 1), at discharge (Group 2) and 3months after discharge (Group 3). We analyzed three age groups: Group65-74, Group75-84 and Group85-up; female and male sex separately; and for severity index value (SI; total cumulative illness rating scale for geriatrics score divided by number of endorsed categories): group between 0-1.99 (SI1) and group ≥2 (SI2). Results: BBS values significantly declined in all male groups and female Group 2 and Group 3 in SI2 (P<0.01). Group65-74 and Group85-up had a significant BBS values decline in Group 2 and Group 3, whereas Group75-84 had a significant decline in all groups in the SI2 group (P<0.01). Females and males had a significant BBS values increase in the SI1 groups (P<0.01), and non-significant BBS values increase between Group 2/Group 3 for SI2. Group85-up had a significant BBS values increase in SI1 (Group 1/Group 2 and Group 1/Group 3; P<0.01); a non-significant increase between Group 1/Group 2 and Group 1/Group 3, and a non-significant decline between Group 2/Group 3 in SI2. Conclusions: Male sex, increased comorbidity and age more than 85years could be considered with lower functional recovery capacity potential after hip fracture, and thus should be individually assessed and continuously monitored. Functional status estimation by BBS could be taken as a sensitive predictive value for the evaluation of functional improvement in these patients. © 2012 Japan Geriatrics Society.
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    Estimation of functional recovery in patients after hip fracture by Berg Balance Scale regarding the sex, age and comorbidity of participants
    (2013)
    Radosavljevic, Natasa (55245822900)
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    Nikolic, Dejan (26023650800)
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    Lazovic, Milica (23497397400)
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    Petronic, Ivana (25121756800)
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    Milicevic, Vera (55292831900)
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    Radosavljevic, Zoran (56107375600)
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    Potic, Jelena (55293803000)
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    Ilic-Stojanovic, Olivera (24401526100)
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    Jeremic, Aleksandar (6701360652)
    Aim: To evaluate the functional status measured by Berg Balance Scale (BBS) in elderly aged more than 65years after hip fractures, and to evaluate the influence of sex, age and comorbidity on balance function improvement. Methods: The study included 203 patients with hip fractures. Functional status was evaluated by BBS: at admission (Group 1), at discharge (Group 2) and 3months after discharge (Group 3). We analyzed three age groups: Group65-74, Group75-84 and Group85-up; female and male sex separately; and for severity index value (SI; total cumulative illness rating scale for geriatrics score divided by number of endorsed categories): group between 0-1.99 (SI1) and group ≥2 (SI2). Results: BBS values significantly declined in all male groups and female Group 2 and Group 3 in SI2 (P<0.01). Group65-74 and Group85-up had a significant BBS values decline in Group 2 and Group 3, whereas Group75-84 had a significant decline in all groups in the SI2 group (P<0.01). Females and males had a significant BBS values increase in the SI1 groups (P<0.01), and non-significant BBS values increase between Group 2/Group 3 for SI2. Group85-up had a significant BBS values increase in SI1 (Group 1/Group 2 and Group 1/Group 3; P<0.01); a non-significant increase between Group 1/Group 2 and Group 1/Group 3, and a non-significant decline between Group 2/Group 3 in SI2. Conclusions: Male sex, increased comorbidity and age more than 85years could be considered with lower functional recovery capacity potential after hip fracture, and thus should be individually assessed and continuously monitored. Functional status estimation by BBS could be taken as a sensitive predictive value for the evaluation of functional improvement in these patients. © 2012 Japan Geriatrics Society.
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    Is abandonment of nonoperative management of hypertrophic pyloric stenosis warranted?
    (2013)
    Lukac, Marija (7003769857)
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    Antunovic, Sanjasindjic (55532726700)
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    Vujovic, Dragana (56513813700)
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    Pavicevic, Polina (25121697400)
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    Jesic, Milos (57211511149)
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    Krstajic, Tamara (36444945000)
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    Petronic, Ivana (25121756800)
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    Nikolic, Dejan (26023650800)
    Aim Evaluation of the effectiveness of oral atropine versus surgical therapy for hypertrophic pyloric stenosis (HPS). Methodology A total of 66 consecutive patients with HPS were treated at the University Children's Hospital between January 2006 and December 2011. The diagnosis was initially based on medical history and confirmed by ultrasonography (US). The patients were divided into two groups according to the treatment preferred by their parents. The conservatively treated group, consisting of 33 boys and 7 girls, mean age 22.25 days, was given water-soluble atropine sulfate therapy at an initial dose of 0.05 mg/kg/day divided into 8 single doses, and administered after stomach decompression, 20 minutes prior to feeding. If vomiting persisted, the daily dose was progressively increased up to 0.18 mg/kg. If vomiting did not stop and full oral feeding was not reestablished in a week, surgery was done. The second group of 26 patients, mean age 20.86 days, underwent an operative procedure, Ramstedt extramucosal pyloromyotomy after the initial resuscitation. US evaluation was performed on days 7, 14, and 21. The outcome of the treatment was tested by Yates modification of the χ2 test. Results In the group of patients treated with atropine sulfate, 10 (25%) failed to respond to therapy, therefore, 8 boys and 2 girls underwent surgical treatment between the fifth and seventh day following institution of therapy. The remaining patients who received atropine sulfate (75%) were discharged when vomiting ceased, between the sixth and eighth day. They continued to take oral medication for 4 to 6 weeks, and were followed up by an ultrasound examination. The operated patients were discharged between the third and fifth day after surgery. There was a significant statistical difference between the groups regarding the outcome at a significance level of p < 0.05 (Yates χ2 = 5.839), with no complications regardless of the treatment option. However, at the significance level of p < 0.01 (Yates χ2 = 7.661), these methods demonstrate a difference in favor of surgical treatment. Conclusion Further investigation of oral, intravenous or combined atropine sulfate treatment may clarify its position as an alternative to pyloromyotomy. © 2013 Georg Thieme Verlag KG Stuttgart - New York.
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    Neurophysiological evaluation in newly diagnosed Diabetes Mellitus type 1
    (2013)
    Matanovic, Dragana (21739989500)
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    Popovic, Srdjan (58426757200)
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    Parapid, Biljana (6506582242)
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    Petronic, Ivana (25121756800)
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    Nikolic, Dejan (26023650800)
    The aim of the study was to evaluate the effects of hyperglycemia on nerve conduction in patients with newly diagnosed diabetes mellitus type 1, and to investigate the significance of early electrophysiological diagnostics in these patients. The study included 85 newly disclosed patients with type 1 diabetes mellitus, in the first three months after the disease. Nerve conduction velocities (NCV) of further nerves were evaluated: median, peroneal, tibial and sural nerve as well as late responses (F-wave and H-reflex). Metabolic control parameters that were evaluated included: glycemia rate on the day of investigation and HbA1c. All patients had poor metabolic control parameters. We found NCV slowing predominantly in the tibial nerve (in 82.4% of patients). Prolonged F-wave latency was disclosed in 72.9% of patients, while H-reflex was evoked in 27.1% of patients only. The most sensitive parameter in the early neurophysiologic diagnostics was the measurement of F-wave latency. Our study underline the significance of early neurophysiological diagnosis, since hyperglycemia can play an acute role in NCV slowing, despite the absence of clinical symptoms, particularly in the first three months after the diagnosis has been confirmed. © 2013 Versita Warsaw and Springer-Verlag Berlin Heidelberg.
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    Physical activity evaluation in Yugoslav Study of the Precursors of Atherosclerosis in School Children - YUSAD study
    (2010)
    Simeunovic, Slavko (6603401374)
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    Milincic, Zeljka (25121732000)
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    Nikolic, Dejan (26023650800)
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    Simeunovic, Dejan (14630934500)
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    Arandjelovic, Dragana (36969676600)
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    Novakovic, Ivana (6603235567)
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    Petronic, Ivana (25121756800)
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    Risimic, Dijana (12773128400)
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    Nedeljkovic, Srecko (7005397351)
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    Vukotic, Milija (7801561823)
    Introduction: It is observed that there is a lack of physical activity and exercise in children, stressing higher prevalence of childhood obesity. The purpose of the study was to evaluate duration of physical activity in a child population and correlation of dynamics in physical activity during 5 years of follow-up in the same population. Material and methods: We evaluated 3243 school children from 12 regional centres across Serbia. The first examination was done when the children were 10 years old (baseline group), while the second examination was done on the same population when children were 15 years old. Physical activity was classified as recreational activity after school. We analysed 3 groups regarding physical activity: a group of children who were physically active less than 1 hour per day (group I), a second group active from 1 hour to < 3 hours per day (group II), and a third group active ≥ 3 hours per day (group III). Results: In our study we have found on examination that the majority of children were physically active between 1 and 3 hours per day. Our results indicate that there is significant movement from groups I and III toward group II on the second examination regarding the proportion in the baseline group. There is a significant increase in the number of children in group I as they get older. Conclusions: School children in Serbia are physically active predominantly between 1 and 3 hours per day at the age between 10 and 15 years. Copyright © 2010 Termedia & Banach.
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    Population genetic analyses of susceptibility to increased body weight
    (2012)
    Nikolic, Dejan (26023650800)
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    Cvjeticanin, Suzana (55924655300)
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    Petronic, Ivana (25121756800)
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    Milincic, Zeljka (25121732000)
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    Brdar, Radivoj (15844992800)
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    Karan, Radmila (47161180600)
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    Konstantinovic, Ljubica (16207335300)
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    Dragin, Aleksandra (57195335175)
    ;
    Cutovic, Milisav (23495402400)
    Introduction: Obesity is a complex condition with multifactorial origin. Assuming that such a state is genetically controlled, the aim of our study was to evaluate the degree of genetic homozygosity among overweight and obese individuals by the homozygously recessive characteristics (HRC) test. Material and methods: We analysed the presence, distribution and individual combination of 15 selected genetically controlled recessive phenotype traits in a sample of 140 individuals with increased body mass index (overweight individuals n = 100 and obese individuals n = 40) and a control group of normal weight individuals (n = 300). Results: Obese individuals have significantly higher mean values for genetic homozygosity than those with normal weight (normal weight:3.61 ±1.48; obese:4.13 ±1.47, p <0.05) and difference in the presence of certain individual combinations of evaluated phenotype traits (Σχ2 = 76.9; p <0.01). There was no difference in average homozygosity of such genetic markers between groups of normal weight and overweight individuals (normal weight:3.61 ±1.48; overweight:3.93 ±1.51, p >0.05) and between groups of overweight and obese individuals (overweight:3.93 ±1.51; obese:4.13 ±1.47, p >0.05). There is no difference in the presence of certain individual combinations of evaluated phenotype traits between overweight and obese individuals (Σχ 2 = 20.6; p >0.05). Conclusions: There is a populational genetic difference in the degree of genetic homozygosity and variability between the group of normal weight and group of obese individuals, indicating a possible genetic component. Overweight and obese individuals have a genetic predisposition, but different expression of genetic loads could be one of the possible explanations for different susceptibility to increase of fat mass and body mass index. Copyright © 2012 Termedia & Banach.
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    Reliability, consistency and temporal stability of Alberta infant motor scale in Serbian infants
    (2020)
    Lackovic, Milan (57218616124)
    ;
    Nikolic, Dejan (26023650800)
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    Filimonovic, Dejan (23990830300)
    ;
    Petronic, Ivana (25121756800)
    ;
    Mihajlovic, Sladjana (57191859364)
    ;
    Golubovic, Zoran (57203254059)
    ;
    Pavicevic, Polina (25121697400)
    ;
    Cirovic, Dragana (25121527800)
    Our study aimed to analyze the reliability, consistency, and temporal stability of the Alberta Infant Motor Scale (AIMS) in Serbian infants. Additionally, we aimed to present a percentile distribution of AIMS in the tested population. The prospective study included 60 infants that were divided into three age groups: 0–3 months, 4–7 months, and 8–14 months. The Serbian version of AIMS was tested by two raters on two different occasions (test/retest) with a five day period between tests. The observed inter-rater reliability (intraclass correlation coefficient (ICC)) was more than 0.75 for all AIMS scores, except for standing (ICC 0.655 = moderate) in the age group of 4–7 months on retest between raters. The observed intra-rater reliability (ICC) was more than 0.75 for all AIMS scores except standing (ICC 0.655 = moderate) in the age group 4–7 months in test–retest for Rater One, and for sitting (ICC 0.671 = moderate) and standing (ICC 0.725 = moderate) in the age group between 0–3 months on test–retest for Rater Two. The Serbian version of AIMS was shown to have high consistency and high reliability with good to high temporal stability. Thus, it can be used in the evaluation of infants’ motor development in Serbia. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
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    Sociodemographic predictors of physical functioning in the elderly: A national health survey
    (2019)
    Kostadinovic, Milena (57205204516)
    ;
    Nikolic, Dejan (26023650800)
    ;
    Petronic, Ivana (25121756800)
    ;
    Cirovic, Dragana (25121527800)
    ;
    Grajic, Mirko (24168219000)
    ;
    Milicevic, Milena Santric (57209748201)
    We aimed to evaluate the prevalence of sociodemographic factors with the presence and different degrees of walking difficulties in elderly above 65 years, and to analyze association between evaluated variables and the presence and degree of waking difficulties. In the population based study, 3540 individuals age above 65 years from Serbia were recruited. Further predictors were analyzed: gender, age, level of education, marital status, body mass index (BMI), index of well-being and place of residence. We assessed difficulty in walking half a km on level ground without the use of any aid (Group-1); and difficulty in walking up or down 12 steps (Group-2). Walking difficulties were categorized as no difficulty, some difficulty, a lot of difficulty and cannot do at all. For present difficulty significant predictors were: age (Group-1 (OR-3.022)/Group-2 (OR-3.825)), gender (Group-1 (OR-0.337)/Group-2 (OR-0.311)), educational level (Group-1 (OR-0.689)/Group-2 (OR-0.556)) and place of residence (Group-2 (OR-1.523)) while for non-performing the task, significant predictors were: age (Group-1 (OR-1.998)/Group-2 (OR-2.096)), gender (Group-1 (OR-0.629)/Group-2 (OR-0.495)), BMI (Group-1 (OR-1.219)/Group-2 (OR-1.305)), marital status (Group-1 (OR 0.764)/Group-2 (OR-0.769)), educational level (Group-1 (OR-0.679)/Group-2 (OR-0.719)) and index of well-being (Group-2 (OR-0.764)). Understanding of predictors, and their role on functional decline in elderly is of great importance for the development of specific population-based health programs to prevent further functional loss and preserve achieved functional gains. © 2018 by the authors. Licensee MDPI, Basel, Switzerland.
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    Sociodemographic predictors of physical functioning in the elderly: A national health survey
    (2019)
    Kostadinovic, Milena (57205204516)
    ;
    Nikolic, Dejan (26023650800)
    ;
    Petronic, Ivana (25121756800)
    ;
    Cirovic, Dragana (25121527800)
    ;
    Grajic, Mirko (24168219000)
    ;
    Milicevic, Milena Santric (57209748201)
    We aimed to evaluate the prevalence of sociodemographic factors with the presence and different degrees of walking difficulties in elderly above 65 years, and to analyze association between evaluated variables and the presence and degree of waking difficulties. In the population based study, 3540 individuals age above 65 years from Serbia were recruited. Further predictors were analyzed: gender, age, level of education, marital status, body mass index (BMI), index of well-being and place of residence. We assessed difficulty in walking half a km on level ground without the use of any aid (Group-1); and difficulty in walking up or down 12 steps (Group-2). Walking difficulties were categorized as no difficulty, some difficulty, a lot of difficulty and cannot do at all. For present difficulty significant predictors were: age (Group-1 (OR-3.022)/Group-2 (OR-3.825)), gender (Group-1 (OR-0.337)/Group-2 (OR-0.311)), educational level (Group-1 (OR-0.689)/Group-2 (OR-0.556)) and place of residence (Group-2 (OR-1.523)) while for non-performing the task, significant predictors were: age (Group-1 (OR-1.998)/Group-2 (OR-2.096)), gender (Group-1 (OR-0.629)/Group-2 (OR-0.495)), BMI (Group-1 (OR-1.219)/Group-2 (OR-1.305)), marital status (Group-1 (OR 0.764)/Group-2 (OR-0.769)), educational level (Group-1 (OR-0.679)/Group-2 (OR-0.719)) and index of well-being (Group-2 (OR-0.764)). Understanding of predictors, and their role on functional decline in elderly is of great importance for the development of specific population-based health programs to prevent further functional loss and preserve achieved functional gains. © 2018 by the authors. Licensee MDPI, Basel, Switzerland.
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    Validation and Cultural Adaptation of the Serbian Version of the Pediatric Outcome Data Collection Instrument (PODCI) in Children with Obstetrical Brachial Plexus Lesion
    (2022)
    Stojkovic, Jasna (57200810273)
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    Cirovic, Dragana (25121527800)
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    Petronic, Ivana (25121756800)
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    Stanisavljevic, Dejana (23566969700)
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    Ducic, Sinisa (22950480700)
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    Jovanovic, Branislav (8242860400)
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    Jovanovic, Jelena Pejanovic (57794119000)
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    Filipovic, Tamara (57191260384)
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    Subotic, Slobodan (57437584100)
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    Nikolic, Dejan (26023650800)
    Background and objectives: Pediatric Outcome Data Collection Instrument (PODCI) is among the most described scales developed to evaluate the physical status of children and adolescents with various musculoskeletal disorders. We aimed to translate PODCI from English to Serbian, culturally adopt items and domains, evaluate the temporal stability, internal consistency and the test–retest reliability of PODCISR in children with obstetrical brachial plexus lesion (OBPL), and finally, to test the construct validity of PODCISR against muscular manual test (MMT) Materials and Methods: The study included 48 eligible participants aged between 2 and 10 years with OBPL. The MMT was used to test the construct validity. Results: There were no significant differences (p > 0.05) between test and retest for all PODCISR domains. Correlations for all tested domains with MMT were statistically significant except for biceps muscle and domains II and IV. Cronbach’s alpha value of the Global Functioning Scale was good and equaled 0.838 for test and 0.832 for retest session. Cronbach’s α was more than 0.600 for all PODCISR domains except for Domain II and for Domain IV. The observed Test–Retest ICC for all PODCISR domains scores ranged from 0.899 to 0.996. Conclusion: The Serbian version of PODCI (PODCISR) was successfully translated and transculturally adopted. It has satisfactory temporal stability, construct validity and test–retest reliability as well as relevant internal consistency. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
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    Validation of serbian version of dysfunctional voiding symptom score (DVSS) questionnaire
    (2018)
    Cirovic, Dragana (25121527800)
    ;
    Petronic, Ivana (25121756800)
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    Nikolic, Dejan (26023650800)
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    Knezevic, Tatjana (25121459700)
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    Vukadinovic, Vojkan (35619008800)
    ;
    Pavicevic, Polina (25121697400)
    Objective: The aims of our study were to translate the dysfunctional voiding symptom score (DVSS) from English to Serbian; culturally adopt the items; assess the internal consistency and the test–retest reliability of DVSSSR in patients with dysfunctional voiding (DV); evaluate and test the construct and divergent validity of DVSSSR against demographic parameters (gender and education); and examine the level of explained variability for each item of DVSSSR against demographic parameters (gender and education). Methods: The cross-sectional observational study included 50 patients with dysfunctional voiding aged 5 years and above. The DVSS questionnaire was translated from English into Serbian by the forward–backward method. Internal consistency was assessed with Cronbach α and test–retest reliability with intraclass correlation coefficient (ICC). For validity testing we performed construct and divergent validity analyses. Results: There was excellent internal consistency for every item except for Item 6 (0.787) and Item 3 (0.864), where internal consistency was good. The observed test/retest ICC for average measures was more than 0.75 (excellent) for all DVSSSR items. Gender and educational level does not correlate significantly with each item of DVSSSR (p > 0.05). For divergent validity, there were no significant differences in mean values of each item of DVSSSR between genders and different levels of education (p > 0.05). Variability that can be explained for gender and educational level was below 10%. Conclusion: Translated DVSSSR is of adequate validity and reliability for assessing DV in children. © 2018 by the authors. Licensee MDPI, Basel, Switzerland.
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    Validity and reliability of the Serbian version of Patient-Reported Impact of Spasticity Measure in multiple sclerosis
    (2015)
    Knezevic, Tatjana (25121459700)
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    Konstantinovic, Ljubica (16207335300)
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    Rodic, Sindi (56241921400)
    ;
    Foti, Calogero (7006569923)
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    Drulovic, Jelena (55886929900)
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    Dackovic, Jelena (19034069600)
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    Nikolic, Dejan (26023650800)
    ;
    Petronic, Ivana (25121756800)
    ;
    Stokic, Dobrivoje S. (7005398132)
    The Patient-Reported Impact of Spasticity Measure (PRISM) has been developed recently to assess the impact of spasticity on quality of life after spinal cord injury. Although PRISM may also be useful in patients with multiple sclerosis (MS), its psychometric properties in MS have not been established and PRISM is currently available only in English. The aims of this cross-sectional study were to translate PRISM into the Serbian language (PRISM SR) and examine its validity (construct, convergent, divergent) and reliability (internal consistency, test-retest reliability) in 48 patients with spasticity because of MS diagnosed at least 1 year earlier and in remission at least 3 months. PRISM SR was administered twice 3 days apart. The validity of seven PRISM SR subscales was examined against the Modified Ashworth Scale (MAS), the Numerical Rating Scale (NRS) for spasticity, sex, and education. Internal consistency was assessed with Cronbach α and test-retest reliability with intraclass correlation coefficient for agreement (ICC 2,1). During the forward-backward translation, only one PRISM item required minor cultural adaption. Almost all PRISM SR scores correlated significantly with MAS and NRS scores (r=0.29-0.51, 0.001≤P≤0.043). They were all significantly higher for MAS≥2 group versus the MAS<2 group (0.003≤P≤0.035) and for the NRS≥7 group versus the NRS<7 group (0.001≤P≤0.042), except for the Social Embarrassment subscale (P=0.083). The PRISM SR scores were not significantly different between sexes (P≥0.104) or those with high school versus college degree (P≥0.139). Both Cronbach α (0.78-0.93) and test-retest ICC 2,1 (0.82-0.90) were high. The original PRISM may be translated successfully into other languages. PRISM SR shows adequate validity and reliability for assessing the impact of spasticity on quality of life in patients with MS. © 2015 Wolters Kluwer Health, Inc.
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    Validity and reliability of the Serbian version of Patient-Reported Impact of Spasticity Measure in multiple sclerosis
    (2015)
    Knezevic, Tatjana (25121459700)
    ;
    Konstantinovic, Ljubica (16207335300)
    ;
    Rodic, Sindi (56241921400)
    ;
    Foti, Calogero (7006569923)
    ;
    Drulovic, Jelena (55886929900)
    ;
    Dackovic, Jelena (19034069600)
    ;
    Nikolic, Dejan (26023650800)
    ;
    Petronic, Ivana (25121756800)
    ;
    Stokic, Dobrivoje S. (7005398132)
    The Patient-Reported Impact of Spasticity Measure (PRISM) has been developed recently to assess the impact of spasticity on quality of life after spinal cord injury. Although PRISM may also be useful in patients with multiple sclerosis (MS), its psychometric properties in MS have not been established and PRISM is currently available only in English. The aims of this cross-sectional study were to translate PRISM into the Serbian language (PRISM SR) and examine its validity (construct, convergent, divergent) and reliability (internal consistency, test-retest reliability) in 48 patients with spasticity because of MS diagnosed at least 1 year earlier and in remission at least 3 months. PRISM SR was administered twice 3 days apart. The validity of seven PRISM SR subscales was examined against the Modified Ashworth Scale (MAS), the Numerical Rating Scale (NRS) for spasticity, sex, and education. Internal consistency was assessed with Cronbach α and test-retest reliability with intraclass correlation coefficient for agreement (ICC 2,1). During the forward-backward translation, only one PRISM item required minor cultural adaption. Almost all PRISM SR scores correlated significantly with MAS and NRS scores (r=0.29-0.51, 0.001≤P≤0.043). They were all significantly higher for MAS≥2 group versus the MAS<2 group (0.003≤P≤0.035) and for the NRS≥7 group versus the NRS<7 group (0.001≤P≤0.042), except for the Social Embarrassment subscale (P=0.083). The PRISM SR scores were not significantly different between sexes (P≥0.104) or those with high school versus college degree (P≥0.139). Both Cronbach α (0.78-0.93) and test-retest ICC 2,1 (0.82-0.90) were high. The original PRISM may be translated successfully into other languages. PRISM SR shows adequate validity and reliability for assessing the impact of spasticity on quality of life in patients with MS. © 2015 Wolters Kluwer Health, Inc.
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