Browsing by Author "Petronic, I. (25121756800)"

Aim. The aim of this study was to evaluate correlation and influence of recreational physical activity during 10 years of follow-up on four types of lipid fractions in school children of the YUSAD study. Methods. School children from Serbia were evaluated on three different occasions when they were 10, 15 and 19/20 years of age, respectively. Four types of lipid fractions, total cholesterol, triglycerides, HDL and LDL, were separately evaluated in physically active boys and girls. Results. We evaluated 1172 children when they were 10 years of age, 870 children when they were 15 and 1230 children when they were 19/20. All children were from the same population. Our results pointed out that there is no linear correlation between the two evaluated variables: physical activity and lipid fractions. However there is a very weak positive or negative correlation of coherence regarding recreational physical activity and the four types of evaluated lipid fractions. Conclusion. Since this period of growth is very specific for metabolic processes that can influence variations of evaluated parameters, such investigation can give us additional knowledge and further directions that could lead to better understanding the correlation of different risk factors on the atherosclerosis development.

Aim. The aim of this study was to evaluate correlation and influence of recreational physical activity during 10 years of follow-up on four types of lipid fractions in school children of the YUSAD study. Methods. School children from Serbia were evaluated on three different occasions when they were 10, 15 and 19/20 years of age, respectively. Four types of lipid fractions, total cholesterol, triglycerides, HDL and LDL, were separately evaluated in physically active boys and girls. Results. We evaluated 1172 children when they were 10 years of age, 870 children when they were 15 and 1230 children when they were 19/20. All children were from the same population. Our results pointed out that there is no linear correlation between the two evaluated variables: physical activity and lipid fractions. However there is a very weak positive or negative correlation of coherence regarding recreational physical activity and the four types of evaluated lipid fractions. Conclusion. Since this period of growth is very specific for metabolic processes that can influence variations of evaluated parameters, such investigation can give us additional knowledge and further directions that could lead to better understanding the correlation of different risk factors on the atherosclerosis development.

Background: Aim of our study was to evaluate degree of genetic homozygosity in male and female gender of spina bifida (SB) occulta and SB aperta patients. Patients and Methods: We evaluated 95 patients with SB occulta and 51 with SB aperta. Degree of genetic homozygosity was evaluated by direct observation of 15 homozygously recessive characteristics (HRC) by HRC-test separately for SB occulta and SB aperta participants. Additionally 370 individuals without SB from Serbia were randomly selected and evaluated as control group. Male and female gender was separately evaluated for assessing degree of genetic homozygosity. Results: There was no significant difference in mean values of HRC between male and female gender in control group (male gender -3.9±1.2, female gender -4.0±1.4, z=0.39; p>0.05), SB occulta (male gender -4.1±1.5, female gender -4.7±1.4, z=1.87, p>0.05) and SB aperta patients (male gender -4.3±1.6, female gender -4.5±1.4, z=0.66, p>0.05), while there was significantly increased recessive homozygosity in female SB occulta group versus control female group (Females: SB occulta -4.7±1.4, Control group -4.0±1.4, z=3.16, p<0.01) and female SB aperta group versus control female group (Females: SB aperta -4.5±1.4, Control group -4.0±1.4, z=2.05, p<0.05). Conclusion: There is increased recessive homozygosity in tested female SB occulta and female SB aperta individuals versus SB male participants and significantly increased recessive homozygosity in female groups of SB patients versus control female group. These findings could lead to the possible assumption that different genes in different degree might be expressed in SB occulta and SB aperta patients.

We compared individual trait variability in 65 male and 81 female patients with spina bifida occulta (SBO) or spina bifida aperta (SBA) against 170 male and 200 female subjects randomly selected Serbian subjects without these conditions. Variability was evaluated by direct observation of 15 homozygous recessive traits (HRT), while gender was evaluated separately. Individual trait variations between genders in SBO patients (4/15 HRT) and in SBA patients (12/15 HRT) showed remarkable differences. Individual trait variations between the male control group and SBO (9/15 HRT), between the female control group and SBO (5/15 HRT), between the male control group and SBA (8/15 HRT), between the female control group and SBA (9/15 HRT), between male SBO and SBA patients (6/15 HRT), between female SBO and SBA patients (6/15 HRT), also indicated remarkable differences. These differences could be explained by different expression of genes that may contribute to expression of spina bifida (SB).

We compared individual trait variability in 65 male and 81 female patients with spina bifida occulta (SBO) or spina bifida aperta (SBA) against 170 male and 200 female subjects randomly selected Serbian subjects without these conditions. Variability was evaluated by direct observation of 15 homozygous recessive traits (HRT), while gender was evaluated separately. Individual trait variations between genders in SBO patients (4/15 HRT) and in SBA patients (12/15 HRT) showed remarkable differences. Individual trait variations between the male control group and SBO (9/15 HRT), between the female control group and SBO (5/15 HRT), between the male control group and SBA (8/15 HRT), between the female control group and SBA (9/15 HRT), between male SBO and SBA patients (6/15 HRT), between female SBO and SBA patients (6/15 HRT), also indicated remarkable differences. These differences could be explained by different expression of genes that may contribute to expression of spina bifida (SB).