Browsing by Author "Pavlovic, Aleksandar D. (57212942710)"

The correlation between substance use and depression has been emphasized in the literature. Substance use disorders can also adversely affect the caregivers of drug-addicted persons. A cross-sectional study was conducted at the Special Hospital for Addiction Diseases in Belgrade in 2015 to analyze the characteristics, consequences, and health-related quality of life of drug users and their caregivers. The sample comprised 136 users of various substances, and 136 caregivers. A questionnaire on socio-demographic characteristics, the Short Form Health Survey 36 (SF-36), and Beck Depression Inventory were administered to all participants. According to multivariate logistic regression analysis, compared with caregivers, substance users were significantly more frequently male (P < .001), ≤ 39 years old (P < .001), and more frequently reported the use of sedatives (P = .009) and smoking (P < .001). Some level of depression was present in all participants, but severe forms were more frequent in substance users (P = .010). Among substance users, mean scores of SF-36 domains ranged from 56.6287.17, and among their caregivers, from 50.3775.07; however, the difference was significant only for the health change domain (P = .037), the score for which was lower in caregivers. Substance users suffered from more severe forms of depression compared to their caregivers, who had lower SF-36 scores in the domain of health change. © 2022 Lippincott Williams and Wilkins. All rights reserved.

Objectives: Determination of smoking habits of medical students in Belgrade and the factors influencing cigarette use. Methods: A cross-sectional study was conducted among undergraduate medical students from all study years at the Faculty of Medicine, University of Belgrade, during the 2015–2016 academic session. A questionnaire, composed of four parts, was administered to all participants: 1. socio-demographic characteristics; 2. habits and lifestyle; 3. Fagerstrom Test for Nicotine Dependence; 4. the Rosenberg self-esteem scale. Logistic regression analysis was conducted to identify the factors significantly associated with cigarette smoking. Results: A total of 2551 subjects, which constituted 81.8% of all undergraduate medical students, participated in the survey. The prevalence of current regular smokers among medical students was 21.7%. The results obtained using the Fagerstrom tolerance scale showed that 41.8% of the students had high nicotine dependence. According to the results of a multivariate analysis, the following were the independent determinants of being a smoker: being male, grade point average of <8/10, daily coffee consumption, self-reported excessive leisure time, self-reported pressure from parents, alcohol consumption, and smokers among parents. Conclusions: Understanding the factors influencing tobacco use is the first step in implementing prevention strategies and can be helpful in the cessation of smoking. © 2021 Taylor & Francis Group, LLC.

Objectives: Determination of smoking habits of medical students in Belgrade and the factors influencing cigarette use. Methods: A cross-sectional study was conducted among undergraduate medical students from all study years at the Faculty of Medicine, University of Belgrade, during the 2015–2016 academic session. A questionnaire, composed of four parts, was administered to all participants: 1. socio-demographic characteristics; 2. habits and lifestyle; 3. Fagerstrom Test for Nicotine Dependence; 4. the Rosenberg self-esteem scale. Logistic regression analysis was conducted to identify the factors significantly associated with cigarette smoking. Results: A total of 2551 subjects, which constituted 81.8% of all undergraduate medical students, participated in the survey. The prevalence of current regular smokers among medical students was 21.7%. The results obtained using the Fagerstrom tolerance scale showed that 41.8% of the students had high nicotine dependence. According to the results of a multivariate analysis, the following were the independent determinants of being a smoker: being male, grade point average of <8/10, daily coffee consumption, self-reported excessive leisure time, self-reported pressure from parents, alcohol consumption, and smokers among parents. Conclusions: Understanding the factors influencing tobacco use is the first step in implementing prevention strategies and can be helpful in the cessation of smoking. © 2021 Taylor & Francis Group, LLC.

A previously known association of tuberculosis (TB), now a global emergency, with diabetes mellitus (DM), a chronic disease of increasing prevalence worldwide, has resurfaced. DM is a recognised TB risk factor and M. tuberculosis infection usually disturbs glycoregulation. We aimed to estimate DM prevalence among TB patients and to analyse clinical and radiologic manifestations of TB in this group. The cross-sectional study included 1017 patients discharged with a TB diagnosis from a tertiary level facility in a five-year period. After exclusion of 128 patients with TB sequelae, we selected 889 patients with confirmed active TB, and the final selection led to 88 subjects with both active TB and DM. DM was found in 9.89% of active TB patients. Testing hypotheses for single-sam-ple proportions showed that the prevalence was significantly higher than the prevalence in the general population (p<0.01). The average patient age was 60.47±14.88 years (range: 20-88), while the male/female ratio was 2.26. We found pulmonary TB in 96.3% of the 88 subjects, and extrapulmonary in 3.4%, the latter more frequently in women (p=0.08). Cavities were more frequently found in tobacco smokers compared to non-smokers (p=0.002) and in patients living in rural settings (p=0.002); haemop-tysis was detected more frequently in men compared to women (p=0.044). Half of the patients had no fever at all, and only 14.8% had tachycardia. Auscultatory findings were positive in 57 (64.8%) patients. Radiographic changes were atypical in 17/88 (19.3%) patients and included pulmonary bases in seven patients, upper lobe anterior segment, and disseminated miliary pattern in two patients. DM prevalence is significantly higher among TB patients compared to the general population. The mean age of TB patients with DM is significantly higher than expected in TB patients alone. Knowledge of TB clinical and radiologic variations in this group of patients may reduce the delay in TB diagnosis with its clinical and epidemiologic consequences. © 2018, EDIMES Edizioni Medico Scientifiche. All rights reserved.