Browsing by Author "Paspalj, Dalibor (55428984400)"

Objective. Hyperbaric oxygen (HBO) has been widely used in people with diseases that cause limb amputation but studies that target patients who underwent amputation itself are rare. The aim of our study was to investigate the effects of HBO on prosthetic rehabilitation in patients with unilateral lower limb amputation. Methods. The study included 60 patients with unilateral (left or right side) lower limb amputation, mean age 61.6 ± 11.5 years, of both genders. They were divided into two groups, the experimental group (with HBO) and the control group (usual care). Patients' functional skills after amputation were evaluated using the LCI test (Locomotor Capabilities Index) and with the classification of Narang and Pohjolainen. Results. Clinical characteristics of patients had relatively homogeneous distribution. After the therapy, a control measurement of both groups showed significantly higher values for LCI test (p <0.01) and lower values for Narang score (p <0.01). However, improvements were more prominent in the group of patients who underwent HBO therapy, therefore, these subjects in the control measurements were evaluated with a statistically significant lower Narang score (p <0.05) and had higher LCI score than the control group patients. Conclusion. HBO is a useful therapeutic measure in the rehabilitation of people with limb amputation who use prosthetic limbs.

Background: We investigated the traditional and new bio- markers as predictors of cardiovascular mortality in the func- tionally disabled elderly who are living in a community. Methods: This prospective study included 253 participants (78.3% women) aged 65 and over who were monitored for 32 months. Receiver operating curve analysis and the Cox proportional hazard model were used to identify univariate and multivariate predictors of cardiovascular mortality. The Kaplan-Meier survival curve and Log rank test were used for survival analysis. Results: During the study, 43.1% participants died from car- diovascular diseases. Cutoff points of multivariate predictors were used to build a score system. The risk score was positive in patients with three or more of the following predictors: albumin <40 g/L, body mass index <25 kg/m2, total serum bilirubin <10.5 (imol/L, blood urea nitrogen >6.5 mmol/L and high-sensitivity C-reactive protein >2.25 mg/L. The rel- ative risk for cardiovascular mortality for someone with a positive vs. negative score was 3.91 (95% Cl: 2.55-5.98; P< 0.001). There was no change in risk after adjustment for age; sex, traditional cardiovascular risk factors, comorbidities and a number of disabilities. Conclusions: Presence of lo* grade inflammation, malnulri tion and early signs of renal dy sfunction are essential for car- diovascular risk among the functional disabled elderly and may be assessed using the proposed new inflammatory m3lnuhffion-renal involved score (1MRIS).

Background: We investigated the traditional and new bio- markers as predictors of cardiovascular mortality in the func- tionally disabled elderly who are living in a community. Methods: This prospective study included 253 participants (78.3% women) aged 65 and over who were monitored for 32 months. Receiver operating curve analysis and the Cox proportional hazard model were used to identify univariate and multivariate predictors of cardiovascular mortality. The Kaplan-Meier survival curve and Log rank test were used for survival analysis. Results: During the study, 43.1% participants died from car- diovascular diseases. Cutoff points of multivariate predictors were used to build a score system. The risk score was positive in patients with three or more of the following predictors: albumin <40 g/L, body mass index <25 kg/m2, total serum bilirubin <10.5 (imol/L, blood urea nitrogen >6.5 mmol/L and high-sensitivity C-reactive protein >2.25 mg/L. The rel- ative risk for cardiovascular mortality for someone with a positive vs. negative score was 3.91 (95% Cl: 2.55-5.98; P< 0.001). There was no change in risk after adjustment for age; sex, traditional cardiovascular risk factors, comorbidities and a number of disabilities. Conclusions: Presence of lo* grade inflammation, malnulri tion and early signs of renal dy sfunction are essential for car- diovascular risk among the functional disabled elderly and may be assessed using the proposed new inflammatory m3lnuhffion-renal involved score (1MRIS).