Browsing by Author "Opancina, Miljan (57192909391)"

Strokes are one of the global leading causes of physical or mental impairment and fatality, classified into hemorrhagic and ischemic strokes. Ischemic strokes happen when a thrombus blocks or plugs an artery and interrupts or reduces blood supply to the brain tissue. Deciding on the imaging modality which will be used for stroke detection depends on the expertise and availability of staff and the infrastructure of hospitals. Magnetic resonance imaging provides valuable information, and its sensitivity for smaller infarcts is greater, while computed tomography is more extensively used, since it can promptly exclude acute cerebral hemorrhages and is more favorable speed-wise. The aim of this article was to give information about the neuroimaging modalities used for the diagnosis and monitoring of ischemic strokes. We reviewed the available literature and presented the use of computed tomography, CT angiography, CT perfusion, magnetic resonance imaging, MR angiography and MR perfusion for the detection of ischemic strokes and their monitoring in different phases of stroke development. © 2023 by the authors.

Background and Objectives: Aneurysmal subarachnoid hemorrhage (ASAH) is defined as bleeding in the subarachnoid space caused by the rupture of a cerebral aneurysm. About 11% of people who develop ASAH die before receiving medical treatment, and 40% of patients die within four weeks of being admitted to hospital. There are limited data on single-center experiences analyzing intrahospital mortality in ASAH patients treated with an endovascular approach. Given that, we wanted to share our experience and explore the risk factors that influence intrahospital mortality in patients with ruptured intracranial aneurysms treated with endovascular coil embolization. Materials and Methods: Our study was designed as a clinical, observational, retrospective cross-sectional study. It was performed at the Department for Radiology, University Clinical Center Kragujevac in Kragujevac, Serbia. The study inclusion criteria were ≥18 years, admitted within 24 h of symptoms onset, acute SAH diagnosed on CT, aneurysm on DSA, and treated by endovascular coil embolization from January 2014 to December 2018 at our institution. Results: A total of 66 patients were included in the study—48 (72.7%) women and 18 (27.3%) men, and 19.7% of the patients died during hospitalization. After adjustment, the following factors were associated with in-hospital mortality: a delayed ischemic neurological deficit, the presence of blood in the fourth cerebral ventricle, and an elevated urea value after endovascular intervention, increasing the chances of mortality by 16.3, 12, and 12.6 times. Conclusions: Delayed cerebral ischemia and intraventricular hemorrhage on initial head CT scan are strong predictors of intrahospital mortality in ASAH patients. Also, it is important to monitor kidney function and urea levels in ASAH patients, considering that elevated urea values after endovascular aneurysm embolization have been shown to be a significant risk factor for intrahospital mortality. © 2024 by the authors.

Up to this date, more than 180 million people worldwide have been affected with COVID-19 and more than 3.9 million people have died. The effect of COVID-19 on thrombosis is well known, and due to this, anticoagulant agents are prescribed. However, the use of anticoagulants is associated with the bleeding trend and occasionally major complications and death outcomes. In this paper, we present the case of a COVID-19 patient treated with anticoagulant therapy who developed Wunderlich’s syndrome. Up to our knowledge, this is the first case of this syndrome in a patient with COVID-19. © Experimental and Applied Biomedical Research.All rights reserved.

Up to this date, more than 180 million people worldwide have been affected with COVID-19 and more than 3.9 million people have died. The effect of COVID-19 on thrombosis is well known, and due to this, anticoagulant agents are prescribed. However, the use of anticoagulants is associated with the bleeding trend and occasionally major complications and death outcomes. In this paper, we present the case of a COVID-19 patient treated with anticoagulant therapy who developed Wunderlich’s syndrome. Up to our knowledge, this is the first case of this syndrome in a patient with COVID-19. © Experimental and Applied Biomedical Research.All rights reserved.