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Browsing by Author "Novaković, Nenad (57190428565)"

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    A Spontaneous Cervical Epidural Hematoma Mimicking a Stroke: A Challenging Case
    (2019)
    Pavlićević, Goran (6603141547)
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    Lepić, Milan (6507064573)
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    Lepić, Toplica (24399616800)
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    Jaćimović, Nemanja (56736738800)
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    Radenović, Ksenija (57193749021)
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    Novaković, Nenad (57190428565)
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    Rasulić, Lukas (6507823267)
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    Mandić-Rajčević, Stefan (49964171500)
    Background: A spontaneous cervical epidural hematoma (SCEH) is a rare occurrence, with < 500 cases reported to date. Clinically, it usually presents with quadriparesis, but in extremely rare cases it can present with hemiparesis or hemiplegia, and can easily be misdiagnosed as stroke. The cervical epidural hematoma by itself is an urgent condition that requires a quick and accurate diagnosis and a prompt surgical treatment. Case Report: We present a case where an SCEH mimicked the much more frequent condition of a stroke, and discuss the importance of diagnostics procedures that help differentiate SCEH from acute cerebral infarction. The patient's history of neck pain and spondylosis render this case more challenging. Why Should an Emergency Physician Be Aware of This?: Considering that the emergency tissue plasminogen activator treatment for acute cerebral infarction can worsen the state of an SCEH patient, or even lead to permanent damage or death, it is of great importance to rapidly and accurately differentiate these two conditions. © 2019 Elsevier Inc.
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    Angiogenic capabilities of omentomyelopexy for injured spinal cord revascularization
    (2018)
    Minić, Ljubodrag (6602719773)
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    Đurović, Branko (12647087400)
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    Lepić, Milan (6507064573)
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    Spaić, Milan (6603635102)
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    Pavlićević, Goran (6603141547)
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    Novaković, Nenad (57190428565)
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    Jaćimović, Nemanja (56736738800)
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    Rasulić, Lukas (6507823267)
    Introduction/Objective Increasing incidence of spinal cord injuries presents a very important issue. These patients are usually very young, treatment is very difficult, long, expensive, and, in general, of little success. The aim of this study was to evaluate the angiogenic potential of the omental graft in spinal cord revascularization after the injury. Methods The study included 19 patients, who underwent a recurrent surgical procedure for pain syndrome or surgical complication, and one patient in whom angiography revealed no flow in the distal part of an omental graft. Results Our study confirmed angiogenic capabilities of the omental graft placed in the course of omentomyelopexy, for the injured spinal cord revascularization, macroscopically and histopathologically. Study results are limited due to including patients only when the postoperative period was complicated. Conclusion Our study provides some invasive insight into the angiogenic capabilities, although further (likely less invasive) studies are needed to elucidate more clearly omental angiogenesis in spinal cord injury, and to include patients in whom the procedure went well. © 2018, Serbia Medical Society. All rights reserved.
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    Awake surgery in sitting position for chronic subdural hematoma
    (2021)
    Lepić, Milan (6507064573)
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    Mandić-Rajčević, Stefan (49964171500)
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    Pavlićević, Goran (6603141547)
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    Novaković, Nenad (57190428565)
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    Rasulić, Lukas (6507823267)
    Background: Chronic subdural hematoma (CSDH) is a common pathology in neurosurgery, especially in the elderly patients, and its incidence is likely to double in the next decade. Considering various features of CSDH and the procedure itself, a sitting position may retain the best characteristics of classic positioning, while offering additional comfort for both the patient and the surgeon. The aim of this study was to describe the technical aspects of this procedure in the sitting position, to evaluate safety and discuss the benefits and shortcomings of this modification. Method: This study included a series of 55 patients surgically treated for CSDH in a sitting position at our department between December 2017 and September 2019, representing all the patients operated on during the study period by a single surgeon. Bilateral hematomas were present in 19 patients. Outcomes, during the 6-month follow-up period, were defined as good (CSDH and symptoms resolved) or poor (lethal outcome or reoccurrence). All complications were noted, with emphasis on pneumocephalus, and complications related to the sitting position: tension pneumocephalus, venous air embolism, and compression nerve injury. Results: Complications previously associated with the sitting position were not noted. The Glasgow Coma Scale and Markwalder Grading Scale scores improved significantly after the surgery (p < 0.001 and p = 0.018). Complications were noted in 17 patients (30.9%), and included 5 cerebrospinal fluid drainages, 3 hematoma reoccurrences, 2 wound infections, and 9 more single-occurring complications. The in-hospital mortality was 5.4% (3 out of 55 patients), while the overall mortality was 16.4% within the 6-month follow-up period. Conclusions: In our series, even the severely ill patients tolerated the position well. No complications associated with the sitting position were noted. Future studies should confirm the safety of this position and evaluate the potential advantages for both the patient and the surgeon. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, AT part of Springer Nature.
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    Cranial reconstruction with prefabricated 3D implant after a gunshot injury - A case report; [Rekonstrukcija defekta lobanje 3D implantatom nakon sklopetarne povrede glave]
    (2016)
    Malivuković, Ana (57190429900)
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    Novaković, Nenad (57190428565)
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    Lepić, Milan (6507064573)
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    Minić, Ljubodrag (6602719773)
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    Stepić, Nenad (6506504302)
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    Djordjević, Boban (36090844000)
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    Rasulić, Lukas (6507823267)
    Introduction. Complex defects of skull bones with different etiology, still present the challenge in reconstructive surgery. The goldstandard for cranioplasty is the autologous calvarial bone graft removed during surgery which cannot be always applied, especially in gunshot wounds for sometimes complete bone destruction. Autologous reconstruction with split calvarial, rib bones or iliac bone graft is also possible. Materials routinely used for reconstructions like titanium mesh, polymethyl metacrylate (PMMA), and other have numerous dis-advantages and limitations. Case report. We presented a patient with gunshot injury to the head with residual large bone defect in the frontal region, with involvement of the skull base, and open frontal sinus. After conservative treatment, six months after the injury, reconstruction of the residual bone defect was performed. The chosen material was computer-designed PEEK-OPTIMA® implant, manufactured on the basis of MSCT scan. This material has not been used in this region so far. The postoperative and follow-up period of the next 12 months passed without surgical complications, neurological deficit, with satisfactory functional and aesthetic results. Conclusion. Implanted bone replacement was designed and manufactured precisely according to the skull defect, and we found it suitable for the treatment of complex defects of the cranium. Early results are in favor of this cranioplasty method over standardized materials. Therefore, this material is expected to become a method of choice for reconstructive surgery of bony defects of the face and skull especially in complex cases. © 2016, Institut za Vojnomedicinske Naucne Informacije/Documentaciju. All rights reserved.
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    Fatal Acute Pneumocephalus after Bilateral Drainage for Chronic Subdural Hematomas: Case Report
    (2022)
    Lepić, Milan (6507064573)
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    Mandić-Rajčević, Stefan (49964171500)
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    Pavlićević, Goran (6603141547)
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    Benović, Radomir (57201634111)
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    Novaković, Nenad (57190428565)
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    Rasulić, Lukas (6507823267)
    Background Pneumocephalus is a well-known complication in the surgical treatment of chronic subdural hematomas; however, its influence remains controversial. The amount of subdural air may vary, and it may cause worsening of symptoms, increase reoccurrence rates, and worsen the outcomes. Lethal outcome following acute onset of massive pneumocephalus was not previously reported. Case Report An 81-year-old man with bilateral hematomas underwent surgery under local anesthesia. Both hematomas were approached in the same surgery, and the drains were placed subdurally. After initial improvement, severe hypertension developed, followed by vital function and neurologic deterioration. Massive pneumocephalus with subarachnoid and contralateral intracerebral hemorrhage was revealed, causing a severe midsagittal shift. Emergency irrigation to evacuate subdural air was performed. However, there was no improvement. Further computed tomography confirmed subdural air collection, but it also revealed hemorrhage progression and intraventricular propagation. No further surgery was indicated. Conclusion Pneumocephalus is an underestimated but potentially devastating complication. Both intraoperative avoidance and postoperative prevention should be utilized to avoid subdural air ingress, and thus evade potentially fatal complications. © 2022 Georg Thieme Verlag. All rights reserved.
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    Management of brachial plexus missile injuries; [Liječenje projektilnih ozljeda brahijalnog pleksusa]
    (2018)
    Rasulić, Lukas (6507823267)
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    Simić, Vesna (57198058627)
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    Savić, Andrija (57191566268)
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    Lepić, Milan (6507064573)
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    Kovačević, Vojin (36190785000)
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    Puzović, Vladimir (55552391000)
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    Vitošević, Filip (57189581968)
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    Novaković, Nenad (57190428565)
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    Samardžić, Miroslav (6603926644)
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    Rotim, Krešimir (6601932997)
    Missile injuries are among the most devastating injuries in general traumatology. Traumatic brachial plexus injuries are the most difficult injuries in peripheral nerve surgery, and most complicated to be surgically treated. Nevertheless, missile wounding is the second most common mechanism of brachial plexus injury. The aim was to evaluate functional recovery after surgical treatment of these injuries. Our series included 68 patients with 202 nerve lesions treated with 207 surgical procedures. Decision on the treatment modality (exploration, neurolysis, graft repair, or com-bination) was made upon intraoperative finding. Results were analyzed in 60 (88.2%) patients with 173 (85.6%) nerve lesions followed-up for two years. Functional recovery was evaluated according to functional priorities. Satisfactory functional recovery was achieved in 90.4% of cases with neurolysis and 85.7% of cases with nerve grafting. Insufficient functional recovery was verified in ulnar and radial nerve lesions after neurolysis, and in median and radial nerve lesions when graft repair was done. We conclude that the best time for surgery is between two and four months after injury, except for the gunshot wound associated with injury to the surrounding structures, which requires immediate surgical treatment. The results of neurolysis and nerve grafting were similar. © 2018, Klinicka Bolnica Sestre Milosrdnice. All rights reserved.
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    Managing Complications Related to Peripheral Nerve Surgery: Selected Illustrative Cases
    (2023)
    Rasulić, Lukas (6507823267)
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    Lepić, Milan (6507064573)
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    Savić, Andrija (57191566268)
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    Novaković, Nenad (57190428565)
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    Kovačević, Vojin (36190785000)
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    Vitošević, Filip (57189581968)
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    Samardžić, Miroslav (6603926644)
    Peripheral nerve surgery mostly involves elective procedures; thus, the associated complications are of great clinical, social, and medicolegal importance. Apart from the general perioperative morbidity, complications during interventions on peripheral nerves are extremely rare. However, iatrogenic peripheral nerve injuries during unrelated surgical procedures performed by those not specialised in peripheral nerve surgery remain the most significant group of complications, accounting for up to approximately 17% of all cases. The aims of this review are to provide better insight into the multifaceted nature of complications related to peripheral nerve surgery—from the perspective of their causes, treatment, and outcome—and to raise surgeons’ awareness of the risks of such morbidity. It should be emphasized that intraoperative complications in peripheral nerve surgery are largely “surgeon-related” rather than “surgery-related”; therefore, they have great potential to be avoided. © 2023, Springer Nature Switzerland AG.
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    Outcome after brachial plexus injury surgery and impact on quality of life
    (2017)
    Rasulić, Lukas (6507823267)
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    Savić, Andrija (57191566268)
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    Živković, Bojana (56464856900)
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    Vitošević, Filip (57189581968)
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    Mićović, Mirko (8943863300)
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    Baščarević, Vladimir (36485908900)
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    Puzović, Vladimir (55552391000)
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    Novaković, Nenad (57190428565)
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    Lepić, Milan (6507064573)
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    Samardžić, Miroslav (6603926644)
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    Mandić-Rajčević, Stefan (49964171500)
    Background: The aim of this study was to investigate outcomes after surgery for brachial plexus injury (BPI), not only motor outcomes but also the quality of life of the patients. Methods: We operated on 128 consecutive patients with BPI from 1992 to 2012. We documented the information on the injured nerve, level of injury, type of treatment used, timing of surgery, patient age, and preoperative and postoperative motor deficits. In 69 patients who agreed to participate in a quality of life study, additional assessments included functionality, pain, quality of life, patient satisfaction, and psychosocial health. Results: Of patients who underwent only exploration and neurolysis, 35.3% showed a good quality of recovery. Patients who underwent nerve reconstruction using nerve grafting showed a better rate of good quality recovery (56.7%), and the results following nerve transfer depended on the type of transfer used. After surgery, 82.6% of patients showed significant improvement, 82.6% were satisfied, and 81.2% responded positively when asked if they would undergo surgery again if they knew the current result beforehand. Overall, 69.6% patients continued working after surgery. The mean DASH disability score was high (58.7) in the study group. Patients who had early surgery showed a consistently higher DASH score. About 76% of patients reported having pain regularly, and 18.8% reported depression or anxiety. Conclusions: We consider that it is important to report not only muscle recovery, but also other aspects of recovery. © 2017, Springer-Verlag Wien.
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    Takotsubo cardiomyopathy in aneurysmal subarachnoid hemorrhage – A case report
    (2019)
    Milaković, Branko (15059321000)
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    Nastasović, Tijana (57195950910)
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    Lepić, Milan (6507064573)
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    Novaković, Nenad (57190428565)
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    Matić, Siniša (57212534659)
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    Savić, Andrija (57191566268)
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    Rasulić, Lukas (6507823267)
    Introduction. Subarachnoid haemorrhage (SAH) can be followed by cardiac abnormalities. We describe a patient with Takotsubo cardiomyopathy and neurogenic pulmonary edema (NPE) after aneurysmal SAH. Case report. A previously healthy, postmenopausal woman, suffered from aneurysmal SAH with consequent hydrocephalus. After external ventricular drainage, craniotomy and clipping of the posterior inferior cerebellar artery aneurysm, the patient developed acute heart failure and NPE. Transthoracic echocardiogram showed the left ventricular apical ballooning and hypercontractile basal segments. On chest radiography, bilateral pulmonary infiltrates were seen. Seventeen days after the SAH attack, the patient was discharged from hospital. Postponed coronary angiography revealed no signs of coronary artery disease. Conclusion. This case and review of the relevant literature suggest that Takotsubo cardiomyopathy and neurogenic pulmonary edema are not uncommon after aneurysmal SAH. © 2019 Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.
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    Useful functional recovery and quality of life after surgical treatment of peroneal nerve injuries
    (2022)
    Rasulić, Lukas (6507823267)
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    Nikolić, Živan (57211598531)
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    Lepić, Milan (6507064573)
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    Savić, Andrija (57191566268)
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    Vitošević, Filip (57189581968)
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    Novaković, Nenad (57190428565)
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    Radojević, Stefan (57393360400)
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    Mićić, Aleksa (57392751000)
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    Lepić, Sanja (57652452400)
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    Mandić-Rajčević, Stefan (49964171500)
    Closed injuries to the peroneal nerve recover spontaneously in about a third of patients, but surgery may be needed in the remaining 2/3. The recovery after surgery is not always satisfactory and the patients may need an orthosis or a walking aid to cope with regular daily activities. This study aimed to evaluate the useful functional recovery and quality of life (QoL) in surgically treated patients with peroneal nerve (PN) injuries. The study involved 51 patients who have undergone surgical treatment due to PN injury in our department, within a 15-year period (2006–2020). Thirty patients (59%) were treated with neurolysis, 12 (23%) with nerve repair techniques, and 9 (18%) with tendon transfer (TT). Neurolysis is employed in the least extensive nerve injuries when nerve continuity is preserved and yields a motor recovery ratio of almost 80%. Nerve repairs were followed by 58.33% of patients achieving M3+ recovery, while 41.66% recovered to the useful functional state (M4 or M5) With the use of TTs, all patients recovered to the M3+, while 66.7% recovered to M4. All our results correspond to the results of previous studies. No statistically significant differences were found regarding the QoL of the groups. There is an apparent advantage of neurolysis, over nerve repair, over TT procedure, both in terms of useful functional recovery, and foot-drop-related QoL. However, when involving all aspects of QoL, these advantages diminish. The individual approach leads to optimal results in all groups of patients. 2022 Rasulić, Nikolić, Lepić, Savić, Vitošević, Novaković, Radojević, Mićić, Lepić and Mandić-Rajčević.
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    Viable C5 and C6 Proximal Stump Use in Reconstructive Surgery of the Adult Brachial Plexus Traction Injuries
    (2020)
    Rasulić, Lukas (6507823267)
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    Savić, Andrija (57191566268)
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    Lepić, Milan (6507064573)
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    Kovačević, Vojin (36190785000)
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    Vitošević, Filip (57189581968)
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    Novaković, Nenad (57190428565)
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    Mandić-Rajčević, Stefan (49964171500)
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    Samardžić, Miroslav (6603926644)
    BACKGROUND: In patients with only upper (C5, C6) brachial plexus palsy (BPP), the pooled international data strongly favor nerve transfers over nerve grafts. In patients with complete BPP, some authors favor nerve grafts for the restoration of priority functions whenever there is a viable proximal stump. OBJECTIVE: To evaluate functional recovery in cases of upper and complete BPP where only direct graft repair from viable proximal stumps was performed. METHODS: The study included 36 patients (24 with complete BPP and 12 with only upper BPP) operated on over a 15-yr period. In all cases, direct graft repair from C5 to the musculocutaneous and the axillary nerve was performed. In cases with complete BPP, additional procedures included either direct graft repair from C6 to the radial nerve and the medial pectoral nerve or the dorsal scapular nerve transfer to the branch for the long head of the triceps. RESULTS: The use of C5 proximal stump grafts (in both complete and upper BPP) resulted in satisfactory elbow flexion in 26 patients (72.2%) and satisfactory shoulder abduction in 22 patients (61.1%). The use of C6 proximal stump grafts in patients with complete BPP resulted in satisfactory elbow extension in 5 (50%) and satisfactory shoulder adduction in another 5 (50%) patients. CONCLUSION: Although nerve transfers generally enable better restoration of priority functions, in cases of infraganglionary injuries, especially in shorter defects, it is also necessary to consider direct graft repair, or at least its combination with nerve transfers, as a potentially beneficial treatment modality. Copyright © 2019 by the Congress of Neurological Surgeons.

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