Browsing by Author "Nejkovic, L. (55566568600)"

Purpose: The study aim was to report an unusual case of a misplaced IUD in isthmico-cervical region causing partial uterine perforation and discuss literature data regarding such a condition. Case Report: A 50-year-old women was referred to the present institution for IUD extraction. She was diagnosed with spontaneously misplaced IUD located in isthmico-cervical region of the uterus causing partial perforation. The time of dislocation was unknown, as she was completely asymptomatic for ten years after IUD application. Moreover, she had no risk factors for device misplacement. The removal of IUD was uneventful. Conclusion: Isthmico-cervical misplacement of IUD, although rare, can occur at any time and can be asymptomatic. Thus, women with IUD should be annually checked-up in order to prevent possible IUD complications.

This is a case report of an extremely rare Carney complex (CNC) syndrome in a 17-year-old patient. After the decision made by a team of cancer specialists, the patient was admitted to the hospital for surgery because of adnexal tumor associated with ascites and increased Ca 125 tumor marker level. The patient underwent cardiac surgery twice. Adnexal mass and ascites, revealed by transvaginal ultrasound (TVUS) and confirmed by magnetic resonance imagings (MRI), indicated the malignant alteration. Surgery was performed and surgical pathological staging was refined according to the FIGO guideline and included a staging laparotomy. After surgery, general condition of the patient was good, without ascites and pain, with Ca 125 marker levels within reference ranges.

Objective: The objective of the present study was to evaluate the accuracy of the sentinel lymph node (SLN) detection procedure in Serbian sample of women with early-stage endometrial cancer (EC). Materials and Methods: In the period from March, 2015 to May 2016, all consecutive patients with histologically confirmed EC, were considered for enrolment in the study. Exclusion criteria included preoperative FIGO Stages II-IV, previous surgery that could influence the uterine lymphatic drainage, history of congenital uterus anomalies, duplex malignancies or deep vein thrombosis on lower extremities, and allergies to the contrast agent. Finally, 27 patients underwent SLN detection, followed by systematic pelvic lymphadenectomy. Demographic, surgical, and pathologic data on all patients were evaluated. Results: The SLNs were identified in 25 patients, with overall detection rate of 92.6%. Twenty-two (81.5%) patients had bilateral, while 11.15% had unilateral intraoperative visualization of SLNs. Of the seven females with positive SLNs, at definitive histology evaluation, pelvic non-SLNs were metastatic in four (57.1%) cases and negative in three (42.9%) cases. The false-negative rate of sentinel procedure was 0%. The evaluation of prognostic values of SLN status, for prediction of presence of metastases in non-SLNs showed the negative predicive value of 100%, and the positive predictive value of 57.1%. Additionally, the sensitivity of SLN method in sample of women with early-stage EC was 100%, while the specificity was 86.9%. Conclusions: SLN procedure has good diagnostic performance and is reliable in prediction of the metastatic status of the regional pelvic lymph nodes in women with early-stage EC.

This is a case report of Herlyn-Werner-Wunderlich syndrome in a 28-year-old patient. She was admitted to hospital for surgical treatment of the pelvic mass accompanied by painful menstruation periods. This syndrome was diagnosed by US and MRI and it was treated by hemi-hysterectomy with vaginectomy. After the surgery, the patient has had regular and painless menstruation.

Purpose: The study aim was to report diagnostic and therapeutic challenges in treatment of a patient with cervical dysplasia and congenital uterine anomaly. Case Report: A 53-year-old women with Mullerian anomaly - uterus duplex (bicorporal septate uterus) and Yshaped endocervical canal was referred due to repeated abnormal Pap smears. She underwent endocervical curettage of both canals and the endocervical septum biopsy which revealed presence of cervical intraepithelial neoplasia (CIN) III. Cervical conization was considered technically unfeasible because of abnormal cervical anatomy (lesions deep in the cervical canal on the cervical bifurcation where the cervical wall is the thickest). Classical open abdominal hysterectomy was performed. Patient had two almost equally-sized, symmetrical uterine bodies connected in the isthmico-cervical region, with normal left and obstructed right hemi-vagina. Postoperative histopathological findings confirmed that dysplasia was located in the region where two endocervical canals conjoined. Conclusion: Diagnostic and therapeutic approach to patients with uterine anomalies has to be individualized, based on anomaly type, patient's age, reproductive history, and patient's preferences.

Objective: Postpartum ovarian vein thrombosis (POVT) is a rare but very dangerous complication with possible lethal outcome. Here the authors present a case of POVT with propagation in cava inferior vein, which was diagnosed fourth day after delivery by cesarean section. Case Report: A 27-year-old female with fever complained of pain in the area of the right side of the abdomen, in the ileocecal region three days after premature delivery by caesarean section. Right ovarian venous thrombosis and partial cava inferior vein thrombosis was demonstrated on sonography and confirmed with computed tomography. She was treated with antibiotics and anticoagulation therapy with good response. Conclusion: If women after delivery have an elevated temperature with abdominal pain and leukocytosis in laboratory analyzes, it is always necessary to think of the POVT. Early recognition and therapy are crucial. © 2020 S.O.G. CANADA Inc.. All rights reserved.

This is a case report of Herlyn-Werner-Wunderlich syndrome in a 28-year old patient. She was admitted to hospital for the surgical treatment of pelvic mass accompanied by painful menstruational periods. This syndrome was diagnosed by ultrasound and MR imaging and it was treated by hemi-hysterectomy with vaginectomy and ovarian resection because of endometriosis. After the surgery, the patient has regular and painless menstruations. © Copyright 2013, CIC Edizioni Internazionali, Roma.

Purpose: The aim of this study was to assess the accuracy of transvaginal ultrasound in detecting endometrial malignancy in perimenopausal women. Material and Methods: The cross-sectional study included 100 perimenopausal women who had changes on the endometrium discovered through a regular ultrasound check-up and were referred to Clinic of Gynecology and Obstetrics "Narodni Front" in Belgrade during the period from September 1, 2012 to September 1, 2013. Transvaginal ultrasound was performed on each participant in the study. Parameters of the ultrasound examination composed a score system. Result: The results of regression analysis showed that this transvaginal ultrasound score have independent prognostic value for detection of endometrial malignancy. Score system showed that the value 8 had the best validity for the detection of endometrial malignity, with the sensitivity of 0.857 and specificity of 0.785. Conclusion: The collected transvaginal ultrasound sample had high predictive value for the discovery of malign changes on endometrium.

The following is a description of an extremely rare tumor of the uterus in a 29-year-old, due to the existence of a 10-millimeter tumor on the uterine corpus, a hysteroscopic resection was performed; and the subsequent pregnancy. A spontaneous desired pregnancy was verified following the first control. © Copyright 2013, CIC Edizioni Internazionali, Roma.

Primary fallopian tube carcinoma is a rare gynecological malignancy and it accounts for about 1% of all gynecological malignancies. Etiological factors are not sufficiently known, but most commonly specified are infertility, nulliparity, and pelvic inflammatory disorder. It is most often asymptomatic, although, a triad reported by Latzko including a vaginal watery discharge, colic like pelvic pain, presence of tumor mass in pelvis, is mentioned as pathognomonic. In the present case, it was primary fallopian tube carcinoma, in FIGO Stage IA. After complete abdominal hysterectomy with lymph node dissection, in line with the expert council’s decision, no adjuvant chemotherapy was administered. PET CT in June 2017, two years after the surgical treatment, presented both some metastatic changes in lungs and enlarged retroperitoneal lymph nodes and after this finding, and chemotherapy with carboplatin was begun. The therapy implies surgical treatment being hysterectomy with adnexectomy, but also retroperitoneal lymph node dissection as well, considering that it more often affects lymphatic glands than epithelial ovarian cancer (EOC). It can be misinterpreted with EOC in a pathological sense. In addition to a surgical treatment, the most common form of chemotherapy is platinum-combined with taxanes. © 2019 S.O.G. CANADA Inc. All rights reserved.