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Browsing by Author "Moellhoff, Nicholas (57211555697)"

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    Publication
    Facial Soft Tissue Repositioning With Neuromodulators: Lessons Learned From Facial Biomechanics
    (2022)
    Hernandez, Claudia A (57213604854)
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    Davidovic, Kristina (55589463300)
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    Avelar, Luiz E. T (57201027881)
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    Alfertshofer, Michael (57220013179)
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    Freytag, David L (57208125545)
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    Frank, Konstantin (56533250000)
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    Moellhoff, Nicholas (57211555697)
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    Bihun, Rebekah (58476959000)
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    Green, Jeremy B (55074762700)
    ;
    Cotofana, Sebastian (35728429400)
    Background: Neuromodulators have proven efficacy in reducing facial rhytides and have also been reported to improve jawline contour and the appearance of platysmal bands. Lifting effects of the tail of the eyebrow are expected outcomes when targeting the lateral periorbital region, underscoring the versatility of neuromodulator treatments. Objectives: The aim of this study was to analyze the clinical effectiveness of a novel neuromodulator-based injection algorithm with regards to its ability to reposition the middle and lower facial soft tissues. Methods: Seventy-five study participants (8 males, 67 females) with a mean [standard deviation] age of 37.5 [8.5] years were injected with neuromodulators in the subdermal plane of the mandibular soft tissues following a standardized algorithm. Live rating of clinical appearance was performed, as well as volume change and skin vector displacement measured by 3-dimensional imaging at baseline, Day 14, and Day 30. Results: Three-dimensional volume analysis revealed an increase in midfacial volume by 0.46 mL, and a decrease of the lower facial volume by 0.30 mL compared with baseline. Additionally, an improvement of midfacial fullness (by 0.13) and jawline contour (by 0.44) was reported on clinical rating scales at Day 30 compared with baseline. Conclusions: Facial soft tissues can be repositioned during the 30-day follow-up period following a neuromodulator treatment; this was reflected through an increase in midfacial volume as well as through a decrease in lower facial volume. The novel injection algorithm presented can provide a safe and effective option for patients desiring improvement of midfacial fullness and jawline contour with neuromodulator treatment alone. © 2022 The Author(s). Published by Oxford University Press on behalf of The Aesthetic Society. All rights reserved.
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    Publication
    How We Look at Mature Faces-An Eye-Tracking Investigation into the Perception of Age
    (2023)
    Frank, Konstantin (56533250000)
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    Ehrl, Denis (54881240900)
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    Bernardini, Francesco (7005332826)
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    Walbrun, Alina (57837745500)
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    Moellhoff, Nicholas (57211555697)
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    Alfertshofer, Michael (57220013179)
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    Davidovic, Kristina (55589463300)
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    Mardini, Samir (56186789100)
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    Gotkin, Robert H (6507175506)
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    Cotofana, Sebastian (35728429400)
    Background: It is still unclear which facial region contributes most to the perception of an aged face when evaluated by eye-Tracking analyses. Objectives: The authors sought to apply eye-Tracking technology to identify whether mature faces require longer fixation durations than young faces and which facial region contributes most to the perception of a mature face. Methods: Eye-Tracking analyses were conducted in 74 volunteers (37 males, 37 females; 43 ≤ 40 years, 31 > 40 years) evaluating their gaze pattern and the fixation durations for the entire face and 9 facial subregions. Frontal facial images of 16 younger (<40 years) and older (>40 years) gender-matched individuals were presented in a standardized setting. Results: Independent of age or gender of the observer, a younger stimulus image was viewed shorter than an older stimulus image with 0.82 (0.63) seconds vs 1.06 (0.73) seconds with P < 0.001. There was no statistically significant difference in their duration of a stable eye fixation when observers inspected a male vs a female stimulus image [0.94 (0.70) seconds vs 0.94 (0.68) seconds; P = 0.657] independent of the observer's age or gender. The facial image that captured the most attention of the observer (rank 9) was the perioral region with 1.61 (0.73) seconds for younger observers and 1.57 (0.73) seconds for older observers. Conclusions: It was revealed that the perioral region attracts the most attention of observers and contributes most to an aged facial appearance. Practitioners should be mindful of the importance of the perioral region when designing an aesthetic treatment plan. © 2022 The Author(s). Published by Oxford University Press on behalf of The Aesthetic Society. All rights reserved.

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