Browsing by Author "Milenkovic, Marina Roksandic (56157719200)"

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Membrane PD-L1 expression and soluble PD-L1 plasma levels in idiopathic pulmonary fibrosis-a pilot study
(2018)
Jovanovic, Dragana (58721901700)
;
Milenkovic, Marina Roksandic (56157719200)
;
Stevuljevic, Jelena Kotur (36629424300)
;
Markovic, Jelena (54793088700)
;
Ceriman, Vesna (57204881031)
;
Kontic, Milica (43761339600)
;
Trifunovic, Vesna Skodric (35273464900)
Background: Idiopathic pulmonary fibrosis (IPF) has common risk factors with cancer and significant similarities in the pathobiology process, both diseases having poor outcomes. Immune checkpoint PD-L1 has become the target of checkpoint inhibitory therapy that unleashes antitumor T cells and has revolutionized cancer treatment. This is a pilot study exploring membrane immune checkpoint PD-L1 expression in human IPF lung tissue samples and its soluble form, soluble PD-L1 (sPD-L1) plasma concentrations in IPF patients, in order to investigate potential role of PD-L1 as an IPF biomarker. © Journal of Thoracic Disease. All rights reserved.