Browsing by Author "Mihajlović, Sladjana (57191859364)"

Introduction. Ovarian endometriosis has been identified as a risk factor for occurrence of endometriosis-associated ovarian carcinoma. We presented a rare case of simultaneous clear cell/ endometrioid ovarian carcinoma and endometriosis of the ipsilateral ovary. Case report. A 47-year- old patient underwent surgery for right ovarian endometriotic cyst. A total hysterectomy with bilateral salpingooophorectomy, lymphadenectomy in the right psoas muscle region and omentectomy were performed as well as multiple peritoneal biopsies. Six cycles of chemotherapy were instituted postoperatively using the Taxol-CBDCA protocol. Abdominal and pelvic CT did not demonstrate recurrence of the disease postoperatively and after completed chemotherapy treatment. Six months after the completion of treatment, the patient felt well without the disease recurrence. Conclusion. Clear cell and endometrioid subtypes of ovarian carcinoma have good prognosis if they are diagnosed and treated at an early stage of the disease. In our patient, the carcinoma was detected in the first stage and successfully treated with combination therapy, i.e., surgical and chemotherapy. Apstrakt Uvod. Endometrioza jajnika je identifikovana kao faktor rizika od nastanka karcinoma jajnika udruženog sa endometriozom. Prikazali smo bolesnicu sa istovremenom pojavom svetloćelijskog/endometrioidnog tipa karcinoma jajnika i endometrioze u istom jajniku. Prikaz bolesnika. Bolesnica, stara 47 godina, podvrgnuta je operativnom zahvatu zbog endometriotične ciste na desnom jajniku. Urađena je histerektomija sa obostranom adneksektomijom, limfadenektomija regije desnog slabinskog mišića, omentektomija i višestruke biopsije peritoneuma. Posle operacije primenjena je hemioterapija u toku šest ciklusa po protokolu Taxol-CBDCA. Nakon hiruškog zahvata i sprovedenog lečenja hemioterapijom urađen je kontrolni CT abdomena i male karlice i kod bolesnice nisu nađeni znakovi recidiva bolesti. Šest meseci posle završenog lečenja bolesnica se dobro osećala i nije imala recidiv bolesti. Zaključak. Svetloćelijski i endometrioidni podtip karcinoma jajnika imaju dobru prognozu ako se otkriju i leče u ranom stadijumu bolesti. Kod prikazane bolesnice karcinom je otkriven u prvom stadijumu i uspešno je lečen kombinovanom terapijom tj. hiruški i hemioterapijom. © 2019, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.

Introduction: Uterus didelphys results when Mullerian duct fusion is completely arrested during development. We presented a rare case of nonobstructive uterus didelphys occurring simultaneously with an endometriotic cyst of the ovary. Case report: A twenty-nine-year-old, nulliparous patient was admitted to our Clinic for laparoscopic treatment of an endometriotic ovarian cyst. Diagnoses of right ovarian endometriotic cyst and nonobstructed uterus didelphys were established with bimanual pelvic exam and two-dimensional transvaginal ultrasound. Diagnoses were subsequently confirmed by laparoscopy and magnetic resonance imaging. Laparoscopic incision and drainage of the endometriotic cyst were performed, followed by biopsy and coagulation of endometriotic lesions. Histopathology confirmed ovarian endometriosis. Gonadotropin-releasing hormone analogue (GnRHa) was prescribed post-operatively, for a total of 3 months. Ten months after completion of treatment, the patients was without disease recurence. Conclusion: Nonobstructive uterus didelphys is rarely associated with ovarian endometriosis. © 2019 Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.