Browsing by Author "Micic, M. (7005218196)"

A 46,XX male (his condition ascertained through evaluation for infertility) underwent clinical, cytogenetic, and endocrinologic analyses, testicular biopsy, and had his permanent tooth sizes measured. The physical examination showed that the patient was smaller than normal and XXY males. The histologic picture was in accordance with well-known characteristics and meiotic analysis revealed no cells in division. The permanent tooth sizes were smaller than male controls. This finding suggests that the genes responsible for the testis-determining factor are present and that the genes influencing tooth size are absent in this patient.

Clinical and meiotic studies were done on an infertile man with a translocation between Yq and 13q, who was identified through the birth of his son with partial trisomy 13q. Seminal plasma transferrin showed preserved Sertoli cell function while lactate dehydrogenase C4 indicated hypospermatogenesis. A quadrivalent in diakinesis and spermatogenic arrest in the second meiotic division was detected. © 1992 Oxford University Press.