Browsing by Author "Mićić, S. (7006493137)"

Congenital absence of both vas deferens accounts for ̃ 10% of cases of obstructive azoospermia. The purpose of the present study was to develop a treatment protocol for a group of azoospermic patients using surgical implantation of alloplastic spermatocoele to enable repeated sperm cell aspiration. Nine patients with congenital absence of both vas deferens, two with obstructed and one with destroyed vas, underwent surgery for the implantation of an alloplastic spermatocoele. In 10 of the 12 patients, vital spermatozoa were recovered from the aspirate and used for intrauterine insemination of their female partners with induced ovulation, some of whom then conceived. © 1990 Oxford University Press.

Summary:  A randomized group of 65 men with oligoasthenozoospermia and left side varicocele was subjected to a controlled study with kallikrein. Kallikrein (600 units orally per day) was given to 38 men for a period of 3 months. The other group of 27 men remained untreated but were followed up during the same period of time. After kallikrein treatment significant improvements in sperm quality could be observed: percentage of motile spermatozoa from 24.47 ± 9.01 to 35.26 ± 11.80, percentage of morphologically normal spermatozoa from 58.42 ± 5.86 to 71.05 ± 8.12. There was no improvement in sperm parameters in the untreated group of men. The results suggest that kallikrein therapy is useful for those men who refuse an operative or radiologic treatment of their varicocele and also as a primary or associated therapy of patients who underwent ligature or occlusion of spermatic veins. Zusammenfassung:  An einer Gruppe von 65 Männern mit Oligoasthenozoospermie und linksseitiger Varicocele wurde eine randomisierte kontrollierte Studie mit Kallikrein durchgeführt. 38 Männer erhielten drei Monate lang täglich 600 Einheiten Kallikrein oral. Die übrigen 27 Männer blieben unbehandelt und bildeten die Vergleichsgruppe. Nach drei Monaten hatten sich bei den Männern der Kallikrein‐Gruppe signifikante Verbesserungen der Spermaqualität ergeben: der Anteil motiler Spermatozoen stieg von 24.47 ± 9.01 auf 35.26 ± 11.80%, der Anteil morphologisch normaler Spermatozoen von 58.42 ± 5.86 auf 71.05 ± 8.12%. Bei der unbehandelten Gruppe zeigten sich keine rele‐vanten Änderungen. Aufgrund dieser Ergebnisse erscheint eine Kallikrein‐Anwendung zum einen sinnvoll bei Männern, die eine operative oder radiologische Behandlung ihrer Varicocele verweigern, zum anderen als primäre oder begleitende Therapie bei Patienten nach durchge‐führter Ligatur oder Okklusion der Vena spermatica. 1990 Blackwell Verlag GmbH

Summary:  A randomized group of 65 men with oligoasthenozoospermia and left side varicocele was subjected to a controlled study with kallikrein. Kallikrein (600 units orally per day) was given to 38 men for a period of 3 months. The other group of 27 men remained untreated but were followed up during the same period of time. After kallikrein treatment significant improvements in sperm quality could be observed: percentage of motile spermatozoa from 24.47 ± 9.01 to 35.26 ± 11.80, percentage of morphologically normal spermatozoa from 58.42 ± 5.86 to 71.05 ± 8.12. There was no improvement in sperm parameters in the untreated group of men. The results suggest that kallikrein therapy is useful for those men who refuse an operative or radiologic treatment of their varicocele and also as a primary or associated therapy of patients who underwent ligature or occlusion of spermatic veins. Zusammenfassung:  An einer Gruppe von 65 Männern mit Oligoasthenozoospermie und linksseitiger Varicocele wurde eine randomisierte kontrollierte Studie mit Kallikrein durchgeführt. 38 Männer erhielten drei Monate lang täglich 600 Einheiten Kallikrein oral. Die übrigen 27 Männer blieben unbehandelt und bildeten die Vergleichsgruppe. Nach drei Monaten hatten sich bei den Männern der Kallikrein‐Gruppe signifikante Verbesserungen der Spermaqualität ergeben: der Anteil motiler Spermatozoen stieg von 24.47 ± 9.01 auf 35.26 ± 11.80%, der Anteil morphologisch normaler Spermatozoen von 58.42 ± 5.86 auf 71.05 ± 8.12%. Bei der unbehandelten Gruppe zeigten sich keine rele‐vanten Änderungen. Aufgrund dieser Ergebnisse erscheint eine Kallikrein‐Anwendung zum einen sinnvoll bei Männern, die eine operative oder radiologische Behandlung ihrer Varicocele verweigern, zum anderen als primäre oder begleitende Therapie bei Patienten nach durchge‐führter Ligatur oder Okklusion der Vena spermatica. 1990 Blackwell Verlag GmbH

Two infertile males with sex chromosomal abnormalities and mosaic karyotype, 45,X/ 46,X,dic(Yq) and 45,X/46,X,ring(Y), had considerably changed physical findings, including tooth sizes and craniofacial dimensions. Spermatogenesis was preserved with abnormal meiotic chromosomal behaviour. Mosaic karyotype and structurally changed Y chromosome in both cases had an influence on physical parameters. Testes were normally developed and spermatogenesis was preserved but depressed in later stages. Copyright © 1990, Wiley Blackwell. All rights reserved

Two infertile males with sex chromosomal abnormalities and mosaic karyotype, 45,X/ 46,X,dic(Yq) and 45,X/46,X,ring(Y), had considerably changed physical findings, including tooth sizes and craniofacial dimensions. Spermatogenesis was preserved with abnormal meiotic chromosomal behaviour. Mosaic karyotype and structurally changed Y chromosome in both cases had an influence on physical parameters. Testes were normally developed and spermatogenesis was preserved but depressed in later stages. Copyright © 1990, Wiley Blackwell. All rights reserved

Seminal plasma FSH, LH, prolactin, testosterone, and oestradiol were estimated in 41 infertile men with varicocele and 45 infertile men without varicocele who failed to impregnate their wives after 2 years of marriage and 30 fertile men. There was significant elevation of FSH in the seminal plasma of the infertile men with varicocele compared with the seminal plasma of the other infertile and fertile men. Seminal LH and prolactin values were similar in both infertile groups but significantly higher than in the fertile men. Testosterone and oestradiol levels in the seminal plasma of infertile men with varicocele were lower than in the fertile and the other infertile males. Finding that both steroids were decreased in infertile men with varicocele could explain disturbed function of spermatozoa in men with varicocele. Further analysis will elucidate the importance of these hormone findings in the seminal plasma of infertile men with varicocele. © 1986 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

Spermatogenesis and meiotic chromosomal behaviour was analysed in a group of males aged 60-80 years. Decreased spermatogenesis was found in most of these aged men although individual differences existed. Chromosomal analysis of cells undergoing diakinesis showed significantly lower chiasma frequency in elderly men, compared with a group of younger control males and also with infertile males. © 1987 IRL Press Limited.