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Browsing by Author "Mandić-Rajčević, Stefan (49964171500)"

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    A review of the diet, nutrients, and supplementation potential for the outcome augmentation in surgical treatment of peripheral nerve injuries
    (2022)
    Lepić, Sanja (57652452400)
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    Lepić, Milan (6507064573)
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    Banjanin, Nikolina (56431133500)
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    Mandić-Rajčević, Stefan (49964171500)
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    Rasulić, Lukas (6507823267)
    Objective: Although the studies have shown the beneficial effects of diet, nutrition, and supplementation as an independent treatment modality, their roles are underestimated in the treatment of peripheral nerve injuries. This is in great part due to the development of efficient nerve repair techniques, combined with physical treatment and stimulation. To achieve the best possible functional recovery diet, nutrition, and supplementation should be implemented within a multidisciplinary approach. The aim of the study is to provide insight into the potentially beneficial effects of diet, nutrients, and supplementation, in the limitation of nerve damage and augmentation of the functional recovery after surgery in a review of human and animal studies. Methods: The data relating to the diet, nutrients, and supplementation effects on peripheral nerve injuries and their treatment was extracted from the previously published literature. Results: General balanced diet as well as obesity influence the initial nerve features prior to the injury. In the period following the injury, neuroprotective agents demonstrated beneficial effects prior to surgery, and immediately after the injury, while those potentiating nerve regeneration may be used after the surgical repair to complement the physical treatment and stimulation for improved functional recovery. Conclusions: Standardized diet, nutrition, and supplementation recommendations and protocols may be of great importance for better nerve regeneration and functional recovery as a part of the multidisciplinary approach to achieve the best possible results in surgically treated patients with peripheral nerve injuries in the future. 2022 Lepić, Lepić, Banjanin, Mandić-Rajčević and Rasulić.
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    A Spontaneous Cervical Epidural Hematoma Mimicking a Stroke: A Challenging Case
    (2019)
    Pavlićević, Goran (6603141547)
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    Lepić, Milan (6507064573)
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    Lepić, Toplica (24399616800)
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    Jaćimović, Nemanja (56736738800)
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    Radenović, Ksenija (57193749021)
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    Novaković, Nenad (57190428565)
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    Rasulić, Lukas (6507823267)
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    Mandić-Rajčević, Stefan (49964171500)
    Background: A spontaneous cervical epidural hematoma (SCEH) is a rare occurrence, with < 500 cases reported to date. Clinically, it usually presents with quadriparesis, but in extremely rare cases it can present with hemiparesis or hemiplegia, and can easily be misdiagnosed as stroke. The cervical epidural hematoma by itself is an urgent condition that requires a quick and accurate diagnosis and a prompt surgical treatment. Case Report: We present a case where an SCEH mimicked the much more frequent condition of a stroke, and discuss the importance of diagnostics procedures that help differentiate SCEH from acute cerebral infarction. The patient's history of neck pain and spondylosis render this case more challenging. Why Should an Emergency Physician Be Aware of This?: Considering that the emergency tissue plasminogen activator treatment for acute cerebral infarction can worsen the state of an SCEH patient, or even lead to permanent damage or death, it is of great importance to rapidly and accurately differentiate these two conditions. © 2019 Elsevier Inc.
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    Awake surgery in sitting position for chronic subdural hematoma
    (2021)
    Lepić, Milan (6507064573)
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    Mandić-Rajčević, Stefan (49964171500)
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    Pavlićević, Goran (6603141547)
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    Novaković, Nenad (57190428565)
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    Rasulić, Lukas (6507823267)
    Background: Chronic subdural hematoma (CSDH) is a common pathology in neurosurgery, especially in the elderly patients, and its incidence is likely to double in the next decade. Considering various features of CSDH and the procedure itself, a sitting position may retain the best characteristics of classic positioning, while offering additional comfort for both the patient and the surgeon. The aim of this study was to describe the technical aspects of this procedure in the sitting position, to evaluate safety and discuss the benefits and shortcomings of this modification. Method: This study included a series of 55 patients surgically treated for CSDH in a sitting position at our department between December 2017 and September 2019, representing all the patients operated on during the study period by a single surgeon. Bilateral hematomas were present in 19 patients. Outcomes, during the 6-month follow-up period, were defined as good (CSDH and symptoms resolved) or poor (lethal outcome or reoccurrence). All complications were noted, with emphasis on pneumocephalus, and complications related to the sitting position: tension pneumocephalus, venous air embolism, and compression nerve injury. Results: Complications previously associated with the sitting position were not noted. The Glasgow Coma Scale and Markwalder Grading Scale scores improved significantly after the surgery (p < 0.001 and p = 0.018). Complications were noted in 17 patients (30.9%), and included 5 cerebrospinal fluid drainages, 3 hematoma reoccurrences, 2 wound infections, and 9 more single-occurring complications. The in-hospital mortality was 5.4% (3 out of 55 patients), while the overall mortality was 16.4% within the 6-month follow-up period. Conclusions: In our series, even the severely ill patients tolerated the position well. No complications associated with the sitting position were noted. Future studies should confirm the safety of this position and evaluate the potential advantages for both the patient and the surgeon. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, AT part of Springer Nature.
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    CLINICAL CHARACTERISTICS AND MORPHOLOGICAL PARAMETERS ASSOCIATED WITH RUPTURE OF ANTERIOR COMMUNICATING ARTERY ANEURYSMS; [POVEZANOST KLINIČKIH KARAKTERISTIKA I MORFOLOŠKIH PARAMETARA S RUPTUROM ANEURIZME PREDNJE KOMUNIKACIJSKE ARTERIJE]
    (2022)
    Vitošević, Filip (57189581968)
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    Medenica, Svetlana Milošević (37061555900)
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    Kalousek, Vladimir (6506067821)
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    Mandić-Rajčević, Stefan (49964171500)
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    Vitošević, Mina (57961369400)
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    Lepić, Milan (6507064573)
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    Rotim, Krešimir (6601932997)
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    Rasulić, Lukas (6507823267)
    We analyzed aneurysm morphology, demographic and clinical characteristics in patients with anterior communicating artery (ACoA) aneurysms to investigate the risk factors contributing to aneurysm rupture. A total of 219 patients with ACoA aneurysms were admitted to our hospital between January 2016 and December 2020, and morphological and clinical characteristics were analyzed retrospectively in 153 patients (112 ruptured and 41 unruptured). Medical records were reviewed to obtain demographic and clinical data on age, gender, presence of hemorrhage, history of hypertension, diabetes, heart disease, and kidney disease. Morphological parameters examined on 3-dimensional digital subtraction angiography included aneurysm size, neck diameter, aspect ratio, size ratio, bottleneck ratio, height/width ratio, aneurysm angle, (in)flow angle, branching angle, number of aneurysms per patient, shape of the aneurysm, aneurysm wall morphology, variation of the A1 segment, and direction of the aneurysm. Male gender, aspect ratio, height/width ratio, non-spherical and irregular shape were associated with higher odds of rupture, whilst controlled hypertension was associated with lower odds of rupture, when tested using univariate logistic regression model. In multivariate model, controlled hypertension, presence of multiple aneurysms, and larger neck diameter reduced the odds of rupture, while irregular wall morphology increased the risk of rupture. Regulated hypertension represented a significant protective factor from ACoA aneurysm rupture. We found that ACoA aneurysms in male patients and those with greater aspect ratios and height/width ratios, larger aneurysm angles, presence of daughter sacs and irregular and non-spherical shapes were at a higher risk of rupture. © 2022, Dr. Mladen Stojanovic University Hospital. All rights reserved.
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    Etiological and epidemiological characteristics of surgically treated radial nerve lesions: A 20-year single-center experience
    (2022)
    Rasulić, Lukas (6507823267)
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    Đjurašković, Slavko (57392750900)
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    Lakićević, Novak (12646882500)
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    Lepić, Milan (6507064573)
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    Savić, Andrija (57191566268)
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    Grujić, Jovan (57218345904)
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    Mićić, Aleksa (57392751000)
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    Radojević, Stefan (57393360400)
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    Córdoba-Mosqueda, María Elena (57192075128)
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    Visani, Jacopo (57204688767)
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    Puzović, Vladimir (55552391000)
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    Kovačević, Vojin (36190785000)
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    Vitošević, Filip (57189581968)
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    Mandić-Rajčević, Stefan (49964171500)
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    Knezevic, Saša (57216621369)
    Introduction: Radial nerve lesions present a clinical entity that may lead to disability, psychological distress, and job loss, and thus requires great attention. Knowledge of the etiology and exact mechanism of the nerve impairment is of great importance for appropriate management of these patients, and there are only a few papers that focused on these features in patients with surgically treated radial nerve lesions. The lack of studies presenting the etiology and injury mechanisms of surgically treated radial nerve lesions may be due to a relatively small number of specialized referral centers, dispersion to low-flow centers, and a greater focus on the surgical treatment outcomes. Aim: The aim of this study was to describe the etiological and epidemiological characteristics of patients with surgically treated radial nerve lesions of various origins. Methods: This retrospective study evaluated 147 consecutive patients with radial nerve lesion, treated in the department during the last 20 years, from January 1, 2001, until December 31, 2020. Results: The majority of patients belonged to the working population, and 70.1% of them were male. Most commonly, the etiology of nerve lesion was trauma (63.3%) or iatrogenic injury (28.6%), while the less common origin was idiopathic (4.1%) or neoplastic (4.1%). The most frequent location of the lesion was in the upper arm, followed by the elbow and forearm. Fracture-related contusion was the most common mechanism (29.9%), followed by postoperative fibrosis (17.7%), lacerations (17.7%), and compression (15.6%). Conclusion: Based on the fact that traumatic or iatrogenic injuries constitute the majority of cases, with their relevant mechanisms and upper arm predomination, it is crucial to raise awareness and understanding of the radial nerve injuries among orthopedic surgeons to decrease the numbers of these patients and properly preserve or treat them within the initial surgery. 2022 Rasulić, Djuraskovic, Lakićević, Lepić, Savić, Grujić, Mićić, Radojevic, Cordoba Mosqueda, Visani, Puzovic, Kovačević, Vitošević, Mandic-Rajcevic and Knezevic.
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    Factors associated with burnout syndrome in primary and secondary school teachers in the republic of srpska (Bosnia and herzegovina)
    (2020)
    Marić, Nada (57226219191)
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    Mandić-Rajčević, Stefan (49964171500)
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    Maksimović, Nataša (12772951900)
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    Bulat, Petar (6603213855)
    Objectives: The aim of this study was to estimate the prevalence of burnout syndrome in a large sample of primary and secondary school teachers in the Republic of Srpska (Bosnia and Herzegovina) and identify the factors associated with burnout in this population. Methods: This cross-sectional study was conducted in August and September of 2018, on a sample of 952 teachers. Beside socio-demographic information, Bortner scale, Job Content Questionnaire, and Maslach Burnout Inventory were filled in by the study participants. Results: Only 5.1% of teachers reported high levels of emotional exhaustion, 3.8% reported high levels of depersonalization, and 22.3% reported low levels of personal accomplishment. Behavior type, specifically type-A behavior, was associated with higher levels of emotional exhaustion. The most important factors associated with burnout were work–life characteristics and job-demand-control model of occupational stress. Conclusions: Our study shows a low prevalence of emotional exhaustion and depersonalization in teachers in the Republic of Srpska before the beginning of the new school year. Since similar studies show a high prevalence of burnout at the end of the school year, a potential seasonality of this syndrome should be considered and explored further. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
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    Factors associated with burnout syndrome in primary and secondary school teachers in the republic of srpska (Bosnia and herzegovina)
    (2020)
    Marić, Nada (57226219191)
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    Mandić-Rajčević, Stefan (49964171500)
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    Maksimović, Nataša (12772951900)
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    Bulat, Petar (6603213855)
    Objectives: The aim of this study was to estimate the prevalence of burnout syndrome in a large sample of primary and secondary school teachers in the Republic of Srpska (Bosnia and Herzegovina) and identify the factors associated with burnout in this population. Methods: This cross-sectional study was conducted in August and September of 2018, on a sample of 952 teachers. Beside socio-demographic information, Bortner scale, Job Content Questionnaire, and Maslach Burnout Inventory were filled in by the study participants. Results: Only 5.1% of teachers reported high levels of emotional exhaustion, 3.8% reported high levels of depersonalization, and 22.3% reported low levels of personal accomplishment. Behavior type, specifically type-A behavior, was associated with higher levels of emotional exhaustion. The most important factors associated with burnout were work–life characteristics and job-demand-control model of occupational stress. Conclusions: Our study shows a low prevalence of emotional exhaustion and depersonalization in teachers in the Republic of Srpska before the beginning of the new school year. Since similar studies show a high prevalence of burnout at the end of the school year, a potential seasonality of this syndrome should be considered and explored further. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
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    Factors Associated with the Antibiotic Treatment of Children Hospitalized for COVID-19 during the Lockdown in Serbia
    (2022)
    Prijić, Andreja (56543420000)
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    Gazibara, Tatjana (36494484100)
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    Prijić, Sergej (20734985500)
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    Mandić-Rajčević, Stefan (49964171500)
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    Maksimović, Nataša (12772951900)
    Unselective use of antibiotics to treat children with COVID-19 is one of the major issues during the pandemic in Serbia. Thus far, there has been no evidence about the predictors of multiple antibiotic use in the treatment of children with COVID-19. The purpose of this study was to assess the prevalence of antibiotic use, as well as to examine demographic and clinical factors associated with a greater number of antibiotics and with a longer antibiotic treatment administered to hospitalized children with COVID-19 during the lockdown in Serbia. This study included all children who were hospitalized from 6 March to 31 May 2020 at the only pediatric COVID-19 hospital, and who were confirmed to have SARS-CoV-2 infection. Demographic, clinical, and laboratory data were collected from medical records. The antibiotic treatment included the use of azithromycin, cephalosporin (ceftriaxone), ampicillin-amikacin, and hydroxychloroquine. The overall prevalence of antibiotics use in children hospitalized with COVID-19 regardless of age was 47.2% (43.3% in children aged 1–5 years and 44.4% in those aged 5–17 years). In children aged 1–5 years, not having a family member affected by COVID-19 (B = −1.38, 95% confidence interval [CI] −2.43, −0.34, p = 0.011), having pneumonia on chest X-ray (B = 0.81, 95%CI 0.34, 1.29, p = 0.002), being a boy (B = −0.65, 95%CI −1.17, −0.13, p = 0.018), and having higher C-reactive protein (CRP) values on admission (B = 0.12, 95%CI 0.07, 0.17, p = 0.001) were associated with the administration of a higher number of antibiotics. These factors, along with having fever (B = 3.20, 95%CI 1.03, 5.37, p = 0.006), were associated with a longer duration of antibiotic treatment in children aged 1–5 years. In children aged 5–17 years, having pharyngeal erythema (B = 1.37, 95%CI 0.61, 2.13, p = 0.001), fever (B = 0.43, 95%CI 0.07, 0.79, p = 0.018), and pneumonia on chest X-ray (B = 0.91, 95%CI 0.53, 1.29, p = 0.001), not having rhinorrhea (B = −1.27, 95%CI −2.47, −0.08, p = 0.037), being a girl (B = 0.52, 95%CI 0.08, 0.97, p = 0.021), and having higher CRP values on admission (B = 0.04, 95%CI 0.01, 0.06, p = 0.006) were associated with the administration of a higher number of antibiotics. These factors, not including the absence of rhinorrhea, were associated with a longer duration of antibiotics treatment in children aged 5–17 years. Demographic, epidemiological, clinical, and laboratory parameters were associated with the use of multiple antibiotics and a longer duration of antibiotic treatment both among children aged 1–5 years and those aged 5–17 years. © 2022 by the authors.
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    Factors Associated with the Antibiotic Treatment of Children Hospitalized for COVID-19 during the Lockdown in Serbia
    (2022)
    Prijić, Andreja (56543420000)
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    Gazibara, Tatjana (36494484100)
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    Prijić, Sergej (20734985500)
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    Mandić-Rajčević, Stefan (49964171500)
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    Maksimović, Nataša (12772951900)
    Unselective use of antibiotics to treat children with COVID-19 is one of the major issues during the pandemic in Serbia. Thus far, there has been no evidence about the predictors of multiple antibiotic use in the treatment of children with COVID-19. The purpose of this study was to assess the prevalence of antibiotic use, as well as to examine demographic and clinical factors associated with a greater number of antibiotics and with a longer antibiotic treatment administered to hospitalized children with COVID-19 during the lockdown in Serbia. This study included all children who were hospitalized from 6 March to 31 May 2020 at the only pediatric COVID-19 hospital, and who were confirmed to have SARS-CoV-2 infection. Demographic, clinical, and laboratory data were collected from medical records. The antibiotic treatment included the use of azithromycin, cephalosporin (ceftriaxone), ampicillin-amikacin, and hydroxychloroquine. The overall prevalence of antibiotics use in children hospitalized with COVID-19 regardless of age was 47.2% (43.3% in children aged 1–5 years and 44.4% in those aged 5–17 years). In children aged 1–5 years, not having a family member affected by COVID-19 (B = −1.38, 95% confidence interval [CI] −2.43, −0.34, p = 0.011), having pneumonia on chest X-ray (B = 0.81, 95%CI 0.34, 1.29, p = 0.002), being a boy (B = −0.65, 95%CI −1.17, −0.13, p = 0.018), and having higher C-reactive protein (CRP) values on admission (B = 0.12, 95%CI 0.07, 0.17, p = 0.001) were associated with the administration of a higher number of antibiotics. These factors, along with having fever (B = 3.20, 95%CI 1.03, 5.37, p = 0.006), were associated with a longer duration of antibiotic treatment in children aged 1–5 years. In children aged 5–17 years, having pharyngeal erythema (B = 1.37, 95%CI 0.61, 2.13, p = 0.001), fever (B = 0.43, 95%CI 0.07, 0.79, p = 0.018), and pneumonia on chest X-ray (B = 0.91, 95%CI 0.53, 1.29, p = 0.001), not having rhinorrhea (B = −1.27, 95%CI −2.47, −0.08, p = 0.037), being a girl (B = 0.52, 95%CI 0.08, 0.97, p = 0.021), and having higher CRP values on admission (B = 0.04, 95%CI 0.01, 0.06, p = 0.006) were associated with the administration of a higher number of antibiotics. These factors, not including the absence of rhinorrhea, were associated with a longer duration of antibiotics treatment in children aged 5–17 years. Demographic, epidemiological, clinical, and laboratory parameters were associated with the use of multiple antibiotics and a longer duration of antibiotic treatment both among children aged 1–5 years and those aged 5–17 years. © 2022 by the authors.
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    Factors influencing utilization of preventive health services in primary health care in the Serbia
    (2021)
    Mitričević, Slavka (57222373183)
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    Janković, Janko (15022715100)
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    Stamenković, Željka (57188960067)
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    Bjegović-Mikanović, Vesna (6602428758)
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    Savić, Marko (57225215986)
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    Stanisavljević, Dejana (23566969700)
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    Mandić-Rajčević, Stefan (49964171500)
    The use of preventive health services is a long-term health investment due to its potential to help individuals to take care of their health. This study aimed to explore the availability and performance of health services in primary health care (PHC) in the domain of general practice (GP), pediatrics, and gynecology, as well as to analyze the influence of sociodemographic and health determinants on the utilization of preventive health services. This descriptive study used data from the National Health Insurance Fund and the Statistical Office of the Serbia for 2015 and included 149 independent PHC units. The relationship between the utilization of preventive services and sociodemographic and health characteristics of the population was analyzed by bivariate and multivariate linear regression models. The higher health expenditure per capita and noncommunicable diseases mortality rate were, the more preventive health services were provided by a chosen GP. Children with a higher completion rate of primary school (p = 0.024), higher health expenditure (p = 0.017), and higher life expectancy at birth (p = 0.041) had more preventive health services. The fertility rate was positively associated with the number of preventive health services per 1000 women (p = 0.033). Our findings should serve as a starting point for where efforts should be made to achieve better health outcomes. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
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    Factors influencing utilization of preventive health services in primary health care in the Serbia
    (2021)
    Mitričević, Slavka (57222373183)
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    Janković, Janko (15022715100)
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    Stamenković, Željka (57188960067)
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    Bjegović-Mikanović, Vesna (6602428758)
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    Savić, Marko (57225215986)
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    Stanisavljević, Dejana (23566969700)
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    Mandić-Rajčević, Stefan (49964171500)
    The use of preventive health services is a long-term health investment due to its potential to help individuals to take care of their health. This study aimed to explore the availability and performance of health services in primary health care (PHC) in the domain of general practice (GP), pediatrics, and gynecology, as well as to analyze the influence of sociodemographic and health determinants on the utilization of preventive health services. This descriptive study used data from the National Health Insurance Fund and the Statistical Office of the Serbia for 2015 and included 149 independent PHC units. The relationship between the utilization of preventive services and sociodemographic and health characteristics of the population was analyzed by bivariate and multivariate linear regression models. The higher health expenditure per capita and noncommunicable diseases mortality rate were, the more preventive health services were provided by a chosen GP. Children with a higher completion rate of primary school (p = 0.024), higher health expenditure (p = 0.017), and higher life expectancy at birth (p = 0.041) had more preventive health services. The fertility rate was positively associated with the number of preventive health services per 1000 women (p = 0.033). Our findings should serve as a starting point for where efforts should be made to achieve better health outcomes. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
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    Fatal Acute Pneumocephalus after Bilateral Drainage for Chronic Subdural Hematomas: Case Report
    (2022)
    Lepić, Milan (6507064573)
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    Mandić-Rajčević, Stefan (49964171500)
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    Pavlićević, Goran (6603141547)
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    Benović, Radomir (57201634111)
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    Novaković, Nenad (57190428565)
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    Rasulić, Lukas (6507823267)
    Background Pneumocephalus is a well-known complication in the surgical treatment of chronic subdural hematomas; however, its influence remains controversial. The amount of subdural air may vary, and it may cause worsening of symptoms, increase reoccurrence rates, and worsen the outcomes. Lethal outcome following acute onset of massive pneumocephalus was not previously reported. Case Report An 81-year-old man with bilateral hematomas underwent surgery under local anesthesia. Both hematomas were approached in the same surgery, and the drains were placed subdurally. After initial improvement, severe hypertension developed, followed by vital function and neurologic deterioration. Massive pneumocephalus with subarachnoid and contralateral intracerebral hemorrhage was revealed, causing a severe midsagittal shift. Emergency irrigation to evacuate subdural air was performed. However, there was no improvement. Further computed tomography confirmed subdural air collection, but it also revealed hemorrhage progression and intraventricular propagation. No further surgery was indicated. Conclusion Pneumocephalus is an underestimated but potentially devastating complication. Both intraoperative avoidance and postoperative prevention should be utilized to avoid subdural air ingress, and thus evade potentially fatal complications. © 2022 Georg Thieme Verlag. All rights reserved.
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    Health workforce management in the context of the COVID-19 pandemic: A survey of physicians in Serbia
    (2021)
    Dinić, Milan (57222631385)
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    Šantrić Milićević, Milena (57211144346)
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    Mandić-Rajčević, Stefan (49964171500)
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    Tripković, Katica (57201397114)
    Background & Aim: The study describes the experiences and opinions of Serbian physicians regarding workforce management during the COVID-19 pandemic. Materials & Methods: A total of 1553 licensed physicians (65% males; average age 44.0 years) responded to an online survey in September 2020. Differences in the respondents' general data and attitudes regarding workforce management and outbreak preparedness in Serbia were analysed in relation to their engagement during the COVID-19 pandemic (Pearson χ2 and the independent samples t-test, p < 0.05). The logistic regression model explained the need for changing health workforce management. Results: The results reveal that the physicians engaged in the fight against the spread of COVID-19 (64.4% of the respondents) more often than their counterparts, were clinicians from the public sector, younger, with less work experience, influenced negatively by the pandemic, and reassigned to other positions (p < 0.001). Health workers dissatisfied with workplace preparedness and those reassigned due to COVID-19 were by 2.61 times and 1.38 times, respectively, more likely than their counterparts to consider changes in health workforce management. Discussion & Conclusion: COVID-19 underlines the need for changes in health workforce management during public health emergencies. An internal incident management team and a panel of external experts may support health workforce management during the prolonged and rapidly changing crises. © 2021 John Wiley & Sons Ltd.
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    Iatrogenic Peripheral Nerve Injuries—Surgical Treatment and Outcome: 10 Years' Experience
    (2017)
    Rasulić, Lukas (6507823267)
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    Savić, Andrija (57191566268)
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    Vitošević, Filip (57189581968)
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    Samardžić, Miroslav (6603926644)
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    Živković, Bojana (56464856900)
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    Mićović, Mirko (8943863300)
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    Baščarević, Vladimir (36485908900)
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    Puzović, Vladimir (55552391000)
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    Joksimović, Boban (15839531700)
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    Novakovic, Nenad (57190428565)
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    Lepić, Milan (6507064573)
    ;
    Mandić-Rajčević, Stefan (49964171500)
    Background Iatrogenic nerve injuries are nerve injuries caused by medical interventions or inflicted accidentally by a treating physician. Methods We describe and analyze iatrogenic nerve injuries in a total of 122 consecutive patients who received surgical treatment at our Institution during a period of 10 years, from January 1, 2003, to December 31, 2013. The final outcome evaluation was performed 2 years after surgical treatment. Results The most common causes of iatrogenic nerve injuries among patients in the study were the operations of bone fractures (23.9%), lymph node biopsy (19.7%), and carpal tunnel release (18%). The most affected nerves were median nerve (21.3%), accessory nerve (18%), radial nerve (15.6%), and peroneal nerve (11.5%). In 74 (60.7%) patients, surgery was performed 6 months after the injury, and in 48 (39.3%) surgery was performed within 6 months after the injury. In 80 (65.6%) patients, we found lesion in discontinuity, and in 42 (34.4%) patients lesion in continuity. The distribution of surgical procedures performed was as follows: autotransplantation (51.6%), neurolysis (23.8%), nerve transfer (13.9%), direct suture (8.2%), and resection of neuroma (2.5%). In total, we achieved satisfactory recovery in 91 (74.6%), whereas the result was dissatisfactory in 31 (25.4%) patients. Conclusions Patients with iatrogenic nerve injuries should be examined as soon as possible by experts with experience in traumatic nerve injuries, so that the correct diagnosis can be reached and the appropriate therapy planned. The timing of reconstructive surgery and the technique used are the crucial factors for functional recovery. © 2017 Elsevier Inc.
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    Measuring the Burden of Infodemics: Summary of the Methods and Results of the Fifth WHO Infodemic Management Conference
    (2023)
    Wilhelm, Elisabeth (57210128701)
    ;
    Ballalai, Isabella (57208671092)
    ;
    Belanger, Marie-Eve (56926282200)
    ;
    Benjamin, Peter (54960310900)
    ;
    Bertrand-Ferrandis, Catherine (58176585500)
    ;
    Bezbaruah, Supriya (57192371802)
    ;
    Briand, Sylvie (27367449600)
    ;
    Brooks, Ian (16159925000)
    ;
    Bruns, Richard (56982591500)
    ;
    Bucci, Lucie M. (56821427000)
    ;
    Calleja, Neville (9740540600)
    ;
    Chiou, Howard (57216585947)
    ;
    Devaria, Abhinav (58176441900)
    ;
    Dini, Lorena (35208397000)
    ;
    D'Souza, Hyjel (58176535900)
    ;
    Dunn, Adam G. (17342099000)
    ;
    Eichstaedt, Johannes C. (55841072400)
    ;
    Evers, Silvia M.A.A. (7102458157)
    ;
    Gobat, Nina (56593233700)
    ;
    Gissler, Mika (7006446486)
    ;
    Gonzales, Ian Christian (57221370987)
    ;
    Gruzd, Anatoliy (23008139300)
    ;
    Hess, Sarah (57196352730)
    ;
    Ishizumi, Atsuyoshi (57215962915)
    ;
    John, Oommen (56592310300)
    ;
    Joshi, Ashish (35269056300)
    ;
    Kaluza, Benjamin (57147649200)
    ;
    Khamis, Nagwa (57225974035)
    ;
    Kosinska, Monika (55428659700)
    ;
    Kulkarni, Shibani (57202575310)
    ;
    Lingri, Dimitra (57188654916)
    ;
    Ludolph, Ramona (56490928900)
    ;
    Mackey, Tim (30067646600)
    ;
    Mandić-Rajčević, Stefan (49964171500)
    ;
    Menczer, Filippo (6701785703)
    ;
    Mudaliar, Vijaybabu (58176683200)
    ;
    Murthy, Shruti (56193736700)
    ;
    Nazakat, Syed (58176349200)
    ;
    Nguyen, Tim (57198024620)
    ;
    Nilsen, Jennifer (57647079000)
    ;
    Pallari, Elena (57188667049)
    ;
    Taschner, Natalia Pasternak (6508352591)
    ;
    Petelos, Elena (54403533300)
    ;
    Prinstein, Mitchell J. (7004860998)
    ;
    Roozenbeek, Jon (57195685297)
    ;
    Schneider, Anton (57191506807)
    ;
    Srinivasan, Varadharajan (58711171500)
    ;
    Stevanović, Aleksandar (57224937156)
    ;
    Strahwald, Brigitte (57188931958)
    ;
    Abdul, Shabbir Syed (47661538800)
    ;
    Machiri, Sandra Varaidzo (57214316292)
    ;
    van der Linden, Sander (54409938000)
    ;
    Voegeli, Christopher (57221092852)
    ;
    Wardle, Claire (36888886200)
    ;
    Wegwarth, Odette (23398957000)
    ;
    White, Becky K. (58380182900)
    ;
    Willie, Estelle (58176442000)
    ;
    Yau, Brian (58039041400)
    ;
    Purnat, Tina D. (56560312300)
    Background: An infodemic is excess information, including false or misleading information, that spreads in digital and physical environments during a public health emergency. The COVID-19 pandemic has been accompanied by an unprecedented global infodemic that has led to confusion about the benefits of medical and public health interventions, with substantial impact on risk-taking and health-seeking behaviors, eroding trust in health authorities and compromising the effectiveness of public health responses and policies. Standardized measures are needed to quantify the harmful impacts of the infodemic in a systematic and methodologically robust manner, as well as harmonizing highly divergent approaches currently explored for this purpose. This can serve as a foundation for a systematic, evidence-based approach to monitoring, identifying, and mitigating future infodemic harms in emergency preparedness and prevention. Objective: In this paper, we summarize the Fifth World Health Organization (WHO) Infodemic Management Conference structure, proceedings, outcomes, and proposed actions seeking to identify the interdisciplinary approaches and frameworks needed to enable the measurement of the burden of infodemics. Methods: An iterative human-centered design (HCD) approach and concept mapping were used to facilitate focused discussions and allow for the generation of actionable outcomes and recommendations. The discussions included 86 participants representing diverse scientific disciplines and health authorities from 28 countries across all WHO regions, along with observers from civil society and global public health–implementing partners. A thematic map capturing the concepts matching the key contributing factors to the public health burden of infodemics was used throughout the conference to frame and contextualize discussions. Five key areas for immediate action were identified. Results: The 5 key areas for the development of metrics to assess the burden of infodemics and associated interventions included (1) developing standardized definitions and ensuring the adoption thereof; (2) improving the map of concepts influencing the burden of infodemics; (3) conducting a review of evidence, tools, and data sources; (4) setting up a technical working group; and (5) addressing immediate priorities for postpandemic recovery and resilience building. The summary report consolidated group input toward a common vocabulary with standardized terms, concepts, study designs, measures, and tools to estimate the burden of infodemics and the effectiveness of infodemic management interventions. Conclusions: Standardizing measurement is the basis for documenting the burden of infodemics on health systems and population health during emergencies. Investment is needed into the development of practical, affordable, evidence-based, and systematic methods that are legally and ethically balanced for monitoring infodemics; generating diagnostics, infodemic insights, and recommendations; and developing interventions, action-oriented guidance, policies, support options, mechanisms, and tools for infodemic managers and emergency program managers. © 2023 JMIR Publications Inc.. All Rights Reserved.
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    Measuring the Burden of Infodemics: Summary of the Methods and Results of the Fifth WHO Infodemic Management Conference
    (2023)
    Wilhelm, Elisabeth (57210128701)
    ;
    Ballalai, Isabella (57208671092)
    ;
    Belanger, Marie-Eve (56926282200)
    ;
    Benjamin, Peter (54960310900)
    ;
    Bertrand-Ferrandis, Catherine (58176585500)
    ;
    Bezbaruah, Supriya (57192371802)
    ;
    Briand, Sylvie (27367449600)
    ;
    Brooks, Ian (16159925000)
    ;
    Bruns, Richard (56982591500)
    ;
    Bucci, Lucie M. (56821427000)
    ;
    Calleja, Neville (9740540600)
    ;
    Chiou, Howard (57216585947)
    ;
    Devaria, Abhinav (58176441900)
    ;
    Dini, Lorena (35208397000)
    ;
    D'Souza, Hyjel (58176535900)
    ;
    Dunn, Adam G. (17342099000)
    ;
    Eichstaedt, Johannes C. (55841072400)
    ;
    Evers, Silvia M.A.A. (7102458157)
    ;
    Gobat, Nina (56593233700)
    ;
    Gissler, Mika (7006446486)
    ;
    Gonzales, Ian Christian (57221370987)
    ;
    Gruzd, Anatoliy (23008139300)
    ;
    Hess, Sarah (57196352730)
    ;
    Ishizumi, Atsuyoshi (57215962915)
    ;
    John, Oommen (56592310300)
    ;
    Joshi, Ashish (35269056300)
    ;
    Kaluza, Benjamin (57147649200)
    ;
    Khamis, Nagwa (57225974035)
    ;
    Kosinska, Monika (55428659700)
    ;
    Kulkarni, Shibani (57202575310)
    ;
    Lingri, Dimitra (57188654916)
    ;
    Ludolph, Ramona (56490928900)
    ;
    Mackey, Tim (30067646600)
    ;
    Mandić-Rajčević, Stefan (49964171500)
    ;
    Menczer, Filippo (6701785703)
    ;
    Mudaliar, Vijaybabu (58176683200)
    ;
    Murthy, Shruti (56193736700)
    ;
    Nazakat, Syed (58176349200)
    ;
    Nguyen, Tim (57198024620)
    ;
    Nilsen, Jennifer (57647079000)
    ;
    Pallari, Elena (57188667049)
    ;
    Taschner, Natalia Pasternak (6508352591)
    ;
    Petelos, Elena (54403533300)
    ;
    Prinstein, Mitchell J. (7004860998)
    ;
    Roozenbeek, Jon (57195685297)
    ;
    Schneider, Anton (57191506807)
    ;
    Srinivasan, Varadharajan (58711171500)
    ;
    Stevanović, Aleksandar (57224937156)
    ;
    Strahwald, Brigitte (57188931958)
    ;
    Abdul, Shabbir Syed (47661538800)
    ;
    Machiri, Sandra Varaidzo (57214316292)
    ;
    van der Linden, Sander (54409938000)
    ;
    Voegeli, Christopher (57221092852)
    ;
    Wardle, Claire (36888886200)
    ;
    Wegwarth, Odette (23398957000)
    ;
    White, Becky K. (58380182900)
    ;
    Willie, Estelle (58176442000)
    ;
    Yau, Brian (58039041400)
    ;
    Purnat, Tina D. (56560312300)
    Background: An infodemic is excess information, including false or misleading information, that spreads in digital and physical environments during a public health emergency. The COVID-19 pandemic has been accompanied by an unprecedented global infodemic that has led to confusion about the benefits of medical and public health interventions, with substantial impact on risk-taking and health-seeking behaviors, eroding trust in health authorities and compromising the effectiveness of public health responses and policies. Standardized measures are needed to quantify the harmful impacts of the infodemic in a systematic and methodologically robust manner, as well as harmonizing highly divergent approaches currently explored for this purpose. This can serve as a foundation for a systematic, evidence-based approach to monitoring, identifying, and mitigating future infodemic harms in emergency preparedness and prevention. Objective: In this paper, we summarize the Fifth World Health Organization (WHO) Infodemic Management Conference structure, proceedings, outcomes, and proposed actions seeking to identify the interdisciplinary approaches and frameworks needed to enable the measurement of the burden of infodemics. Methods: An iterative human-centered design (HCD) approach and concept mapping were used to facilitate focused discussions and allow for the generation of actionable outcomes and recommendations. The discussions included 86 participants representing diverse scientific disciplines and health authorities from 28 countries across all WHO regions, along with observers from civil society and global public health–implementing partners. A thematic map capturing the concepts matching the key contributing factors to the public health burden of infodemics was used throughout the conference to frame and contextualize discussions. Five key areas for immediate action were identified. Results: The 5 key areas for the development of metrics to assess the burden of infodemics and associated interventions included (1) developing standardized definitions and ensuring the adoption thereof; (2) improving the map of concepts influencing the burden of infodemics; (3) conducting a review of evidence, tools, and data sources; (4) setting up a technical working group; and (5) addressing immediate priorities for postpandemic recovery and resilience building. The summary report consolidated group input toward a common vocabulary with standardized terms, concepts, study designs, measures, and tools to estimate the burden of infodemics and the effectiveness of infodemic management interventions. Conclusions: Standardizing measurement is the basis for documenting the burden of infodemics on health systems and population health during emergencies. Investment is needed into the development of practical, affordable, evidence-based, and systematic methods that are legally and ethically balanced for monitoring infodemics; generating diagnostics, infodemic insights, and recommendations; and developing interventions, action-oriented guidance, policies, support options, mechanisms, and tools for infodemic managers and emergency program managers. © 2023 JMIR Publications Inc.. All Rights Reserved.
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    Occupational exposure to blood and bodily fluids among healthcare workers in Serbian general hospitals
    (2018)
    Mandić, Bojana (57201792732)
    ;
    Mandić-Rajčević, Stefan (49964171500)
    ;
    Marković-Denić, Ljiljana (55944510900)
    ;
    Bulat, Petar (6603213855)
    The risk of occupational bloodborne infections (HBV, HCV, and HIV) among healthcare workers remains a serious issue in developing countries. The aim of this study was to estimate occupational exposure to bloodborne infections among general hospital workers in Serbia. This cross-sectional study was conducted in the spring of 2013 and included 5,247 healthcare workers from 17 general hospitals. The questionnaire was anonymous, self-completed, and included socio-demographic information with details of blood and bodily fluid exposure over the career and in the previous year (2012). Significant predictors of sharps injuries were determined with multiple logistic regressions. The distribution of accidents in 2012 was equal between the genders (39 %), but in entire career it was more prevalent in women (67 %). The most vulnerable group were nurses. Most medical doctors, nurses, and laboratory technicians reported stabs or skin contact with patients’ blood/other bodily fluid/tissue as their last accident. Healthcare workers from the north/west part of the country reported a significantly lower number of accidents over the entire career than the rest of the country (p<0.001). The south of Serbia stood out as the most accident-prone in 2012 (p=0.042). © 2018 Institute for Medical Research and Occupational Health. All rights reserved.
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    Occupational exposure to blood and bodily fluids among healthcare workers in Serbian general hospitals
    (2018)
    Mandić, Bojana (57201792732)
    ;
    Mandić-Rajčević, Stefan (49964171500)
    ;
    Marković-Denić, Ljiljana (55944510900)
    ;
    Bulat, Petar (6603213855)
    The risk of occupational bloodborne infections (HBV, HCV, and HIV) among healthcare workers remains a serious issue in developing countries. The aim of this study was to estimate occupational exposure to bloodborne infections among general hospital workers in Serbia. This cross-sectional study was conducted in the spring of 2013 and included 5,247 healthcare workers from 17 general hospitals. The questionnaire was anonymous, self-completed, and included socio-demographic information with details of blood and bodily fluid exposure over the career and in the previous year (2012). Significant predictors of sharps injuries were determined with multiple logistic regressions. The distribution of accidents in 2012 was equal between the genders (39 %), but in entire career it was more prevalent in women (67 %). The most vulnerable group were nurses. Most medical doctors, nurses, and laboratory technicians reported stabs or skin contact with patients’ blood/other bodily fluid/tissue as their last accident. Healthcare workers from the north/west part of the country reported a significantly lower number of accidents over the entire career than the rest of the country (p<0.001). The south of Serbia stood out as the most accident-prone in 2012 (p=0.042). © 2018 Institute for Medical Research and Occupational Health. All rights reserved.
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    Outcome after brachial plexus injury surgery and impact on quality of life
    (2017)
    Rasulić, Lukas (6507823267)
    ;
    Savić, Andrija (57191566268)
    ;
    Živković, Bojana (56464856900)
    ;
    Vitošević, Filip (57189581968)
    ;
    Mićović, Mirko (8943863300)
    ;
    Baščarević, Vladimir (36485908900)
    ;
    Puzović, Vladimir (55552391000)
    ;
    Novaković, Nenad (57190428565)
    ;
    Lepić, Milan (6507064573)
    ;
    Samardžić, Miroslav (6603926644)
    ;
    Mandić-Rajčević, Stefan (49964171500)
    Background: The aim of this study was to investigate outcomes after surgery for brachial plexus injury (BPI), not only motor outcomes but also the quality of life of the patients. Methods: We operated on 128 consecutive patients with BPI from 1992 to 2012. We documented the information on the injured nerve, level of injury, type of treatment used, timing of surgery, patient age, and preoperative and postoperative motor deficits. In 69 patients who agreed to participate in a quality of life study, additional assessments included functionality, pain, quality of life, patient satisfaction, and psychosocial health. Results: Of patients who underwent only exploration and neurolysis, 35.3% showed a good quality of recovery. Patients who underwent nerve reconstruction using nerve grafting showed a better rate of good quality recovery (56.7%), and the results following nerve transfer depended on the type of transfer used. After surgery, 82.6% of patients showed significant improvement, 82.6% were satisfied, and 81.2% responded positively when asked if they would undergo surgery again if they knew the current result beforehand. Overall, 69.6% patients continued working after surgery. The mean DASH disability score was high (58.7) in the study group. Patients who had early surgery showed a consistently higher DASH score. About 76% of patients reported having pain regularly, and 18.8% reported depression or anxiety. Conclusions: We consider that it is important to report not only muscle recovery, but also other aspects of recovery. © 2017, Springer-Verlag Wien.
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    Pediatric dentists’ service provisions in south-east europe during the first wave of covid-19 epidemic: Lessons learned about preventive measures and personal protective equipment use
    (2021)
    Vuković, Ana (57189182795)
    ;
    Mandić-Rajčević, Stefan (49964171500)
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    Sava-Rosianu, Ruxandra (55201205800)
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    Betancourt, Marcela D. (57218435179)
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    Xhajanka, Edit (57202352836)
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    Hysenaj, Neada (57327893500)
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    Bajric, Elmedin (54413778000)
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    Zukanović, Amila (17136625800)
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    Philippides, Vrassidas (57327327800)
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    Zosimas, Marios (57327327900)
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    Nikolaos, Maroufidis (23994019400)
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    Vlahović, Zoran (6506607133)
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    Denkovski, Marijan (57220779033)
    ;
    Peric, Tamara (18134053000)
    ;
    Markovic, Dejan (18133990000)
    ;
    Campus, Guglielmo (7006016308)
    Introduction: Having in mind the importance of providing continuous pediatric dental services during the COVID-19 pandemic and the fact that children have similar viral loads to adults, the potential to spread the virus to others, and with variable clinical presentation of COVID-19 in-fection, this study aimed to analyze the impact of COVID-19 outbreak on pediatric dentistry service provision, risks, and preventive measures before and during dental treatment. Method: Structured and closed epidemiological cross-sectional survey involved seven Southeastern European coun-tries. The questionnaire was developed using the modified Delphi method, pretested, and tested in North Italy during April 2020. The sample consisted of licensed dental professionals reached via national dental chambers and social media using the best strategies according to the national setting. Results: A total of 3227 dentists participated in the survey, and we included 643 specialists in this study—among them, 164 were pediatric dentists. Most pediatric dentists worked in the public sec-tor (61.0%) and provided emergency (64.6%) and routine dental treatment (18.3%) during the out-break. One-third of pediatric dentists were COVID-19 tested, statistically significantly more than other specialties, and 3.0% tested COVID-19 positive. In addition, significantly more pediatric dentists (13.4%) reported the presence of at least one symptom related to COVID-19 compared to other specialists (6.1%). None of the pediatric dentists reported PPE shortage. However, 26.2% of all specialists stated that they lacked clear step by step professional guidance in a national language. Sim-ilarly, in both groups, around 10% of specialists attended education on coronavirus. Conclusions: Considering that most pediatric dentists provided dental treatment during lockdown in their countries in public health centers and that they will continue to work during pandemic, our results suggest that pediatric dentists might be at higher risk of COVID-19 infection. Further research should focus on finding better ways to promote and adapt preventive, protective measures and PPE in the pediatric dental setting to be behaviorally acceptable. Moreover, additional efforts should be invested in dental education regarding COVID-19 in the mother tongue. © 2021 by the author. Licensee MDPI, Basel, Switzerland.
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