Browsing by Author "Maksimovic, Milos Z. (13613612200)"

Purpose: To compare the prevalence and severity of depression and anxiety among patients with vocal fold (VF) nodules, polyps and edema. At the same time the aim was to analyse association between severity of distress and the level of vocal handicap as well as to identify other factors related to severity of depression and anxiety in these patients. Methods: To all participants were given five questionnaires: (1) questionnaire on socio-demographic and some other characteristics of patient; (2) Beck's Depression Inventory (BDI); (3) State–Trait Anxiety Inventory (STAI) 1 (State Anxiety); (4) STAI 2 (Trait Anxiety); and (5) Voice Handicap Index (VHI)-10. Results: A total of 205 patients were included in this study. Mild-to-severe depression, according to BDI was present in 79 (38.6%) patients. Mild-to-severe state anxiety and trait anxiety were present in 199 (97.1%) and 200 (97.6%) patients, respectively. Only 10 patients had VHI-10 score ≤ 11. Multivariate analyses showed that there were no significant differences in the level of depression and anxiety between patients with VF nodules, polyps and edema. The VHI-10 score was significantly higher in patients with VF edema in comparison with VF nodule patients (p = 0.001), as well as in comparison with VF polyp patients (p = 0.001). Conclusion: The present study identified a high prevalence of psychological and vocal distress among patients with vocal disorders. Severity of depression and anxiety did not differ between patients with VF nodules, polyps and edema, and it was not related to the level of vocal handicap. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature.

Objective: Although C-reactive protein (CRP) is among the best cardiovascular disease risk predictors, data regarding the association of CRP and menopause are controversial. In this study, we measured CRP by a high-sensitivity method (hsCRP), cholesterol, lipoproteins, and triglycerides in normal and overweight postmenopausal women. Methods: Body weight, height, waist circumference (WC), hsCRP, total cholesterol, high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), triglycerides, and lipoprotein (a) were measured in 30 normal weight and 60 overweight healthy postmenopausal women. Results: Significantly higher triglyceride and hsCRP levels (P=0.005 and P<0.001 respectively), together with lower HDL-c levels (P=0.001) were found in overweight compared to normal weight women. In the overweight group, positive correlations of hsCRP were observed with age, body mass index and WC (P=0.016, P=0.001, and P<0.001, respectively) and a negative correlation was observed with HDL-c (P=0.007). In the normal weight group, positive correlations were found for hsCRP with age and WC (P=0.023 and P=0.014, respectively). WC was the best predictor of hsCRP level in both groups (P<0.001). Conclusion: Elevated hsCRP levels in conjunction with abnormal lipid profiles may be strongly associated with weight gain in postmenopausal women. Efforts to reduce obesity and inflammation in this group may help correct abnormal levels of hsCRP and lipids. © 2014, American Society of Clinical Pathologists. All rights reserved.

Objectives: Determination of smoking habits of medical students in Belgrade and the factors influencing cigarette use. Methods: A cross-sectional study was conducted among undergraduate medical students from all study years at the Faculty of Medicine, University of Belgrade, during the 2015–2016 academic session. A questionnaire, composed of four parts, was administered to all participants: 1. socio-demographic characteristics; 2. habits and lifestyle; 3. Fagerstrom Test for Nicotine Dependence; 4. the Rosenberg self-esteem scale. Logistic regression analysis was conducted to identify the factors significantly associated with cigarette smoking. Results: A total of 2551 subjects, which constituted 81.8% of all undergraduate medical students, participated in the survey. The prevalence of current regular smokers among medical students was 21.7%. The results obtained using the Fagerstrom tolerance scale showed that 41.8% of the students had high nicotine dependence. According to the results of a multivariate analysis, the following were the independent determinants of being a smoker: being male, grade point average of <8/10, daily coffee consumption, self-reported excessive leisure time, self-reported pressure from parents, alcohol consumption, and smokers among parents. Conclusions: Understanding the factors influencing tobacco use is the first step in implementing prevention strategies and can be helpful in the cessation of smoking. © 2021 Taylor & Francis Group, LLC.

Objectives: Determination of smoking habits of medical students in Belgrade and the factors influencing cigarette use. Methods: A cross-sectional study was conducted among undergraduate medical students from all study years at the Faculty of Medicine, University of Belgrade, during the 2015–2016 academic session. A questionnaire, composed of four parts, was administered to all participants: 1. socio-demographic characteristics; 2. habits and lifestyle; 3. Fagerstrom Test for Nicotine Dependence; 4. the Rosenberg self-esteem scale. Logistic regression analysis was conducted to identify the factors significantly associated with cigarette smoking. Results: A total of 2551 subjects, which constituted 81.8% of all undergraduate medical students, participated in the survey. The prevalence of current regular smokers among medical students was 21.7%. The results obtained using the Fagerstrom tolerance scale showed that 41.8% of the students had high nicotine dependence. According to the results of a multivariate analysis, the following were the independent determinants of being a smoker: being male, grade point average of <8/10, daily coffee consumption, self-reported excessive leisure time, self-reported pressure from parents, alcohol consumption, and smokers among parents. Conclusions: Understanding the factors influencing tobacco use is the first step in implementing prevention strategies and can be helpful in the cessation of smoking. © 2021 Taylor & Francis Group, LLC.

Objectives: The aim of the present study was to estimate risk factors for type 2 diabetes in women. Methods: A case–control study included 99 newly diagnosed cases of type 2 diabetes and 198 controls. Descriptive statistics were used, and conditional univariate logistic regression analysis was used to determine differences between cases and controls. Results: According to multivariate analysis-independent risk factors for T2DM were as follows: oral contraceptives (OR = 2.57; 95% CI = 0.99–6.62), and their longer duration of use (OR = 3.55; 95% CI = 1.79–6.99); greater quantity of coffee consumed (OR = 1.89; 95% CI = 1.06–3.39), occupation (odds ratio–OR = 3.17; 95% confidence interval–CI = 1.57–6.41); never been pregnant (OR = 5.88; 95% CI = 2.23–15.49); family history of diabetes (OR = 18.52; 95% CI = 7.25–47.62); overweight and obesity (OR = 2.13, 95% CI = 1.39–4.53); stress (OR = 4.42; 95% CI = 2.19–8.26), and the greater number of stressful life event (OR = 1.65; 95% CI = 1.22–2.23). Conclusions: The present study emphasizes the role of oral contraceptive use, a greater quantity of coffee consumed, occupation, never been pregnant, overweight and obesity, major stressful life events, and family history of diabetes in the development of type 2 diabetes. © 2023 Taylor & Francis Group, LLC.

Objectives: The aim of the present study was to estimate risk factors for type 2 diabetes in women. Methods: A case–control study included 99 newly diagnosed cases of type 2 diabetes and 198 controls. Descriptive statistics were used, and conditional univariate logistic regression analysis was used to determine differences between cases and controls. Results: According to multivariate analysis-independent risk factors for T2DM were as follows: oral contraceptives (OR = 2.57; 95% CI = 0.99–6.62), and their longer duration of use (OR = 3.55; 95% CI = 1.79–6.99); greater quantity of coffee consumed (OR = 1.89; 95% CI = 1.06–3.39), occupation (odds ratio–OR = 3.17; 95% confidence interval–CI = 1.57–6.41); never been pregnant (OR = 5.88; 95% CI = 2.23–15.49); family history of diabetes (OR = 18.52; 95% CI = 7.25–47.62); overweight and obesity (OR = 2.13, 95% CI = 1.39–4.53); stress (OR = 4.42; 95% CI = 2.19–8.26), and the greater number of stressful life event (OR = 1.65; 95% CI = 1.22–2.23). Conclusions: The present study emphasizes the role of oral contraceptive use, a greater quantity of coffee consumed, occupation, never been pregnant, overweight and obesity, major stressful life events, and family history of diabetes in the development of type 2 diabetes. © 2023 Taylor & Francis Group, LLC.

Background: Metabolic syndrome (MetS) has been related to type 2 diabetes and cardiovascular diseases. Different criteria for diagnosis of MetS have been recommended, but there is no agreement about which criteria are best to use. The aim of the present study was to investigate agreement between the National Heart, Lung, and Blood Institute, American Heart Association (NHLBI/AHA) and the International Diabetes Federation (IDF) definitions of MetS in patients with symptomatic carotid disease and to compare the frequency of cardiovascular risk factor in patients with MetS diagnosed by these two sets of criteria.Methods: The study was a cross-sectional one involving 644 consecutive patients with verified carotid disease who referred to the Vascular Surgery Clinic Dedinje in Belgrade during the period April 2006 - November 2007. Anthropometric parameters blood pressure, fasting plasma glucose and lipoproteins were measured using standard procedures.Results: MetS was present in 67.9% of participants, according to IDF criteria, and in 64.9% of participants, according to the NHLBI/AHA criteria. A total of 119 patients were categorized differently by the two definitions. Out of all participants 10.7% had MetS by IDF criteria only and 7.8% of patients had MetS by NHLBI/AHA criteria only. The overall agreement of IDF and NHLBI/AHA criteria was 81.5% (Kappa 0.59, p < 0.001). In comparison with patients who met only IDF criteria, patients who met only NHLBI/AHA criteria had significantly more frequently cardiovascular risk factors with the exception of obesity which was significantly more frequent in patients with MetS diagnosed by IDF criteria.Conclusion: The MetS prevalence in patients with symptomatic carotid disease was high regardless of criteria used for its diagnosis. Since some patients with known cardiovascular risk factors were lost by the use of IDF criteria it seems that NHLBI/AHA definition is more suitable for diagnosis of MetS. Large follow-up studies are needed to test prognostic value of these definitions. © 2012 Maksimovic et al; licensee BioMed Central Ltd.