Browsing by Author "Ille, Tanja (24830425500)"

Objective: This study is an investigation of parasuicidal presentations in young people in Bosnia during the period from 1992 to 2004. The other aims were: an analysis of the stress as well as the personal and emotional traits of suicidal subjects. Methods: Two groups of young people were investigated: 90 with parasuicidal caracteristics and 90 controls who had experienced emotional and behavioral crises during adolescence. The study is longitudinal and stratified according to the qualities of the parasuicidal behaviour. The tests used in this study (LOP, Ci, CMI, EPQ-98 and P.I.E.) are statistically elaborated by standard descriptive and analytical methods. Results: The results show the following factors to be highly significant: destruction and violence inside the families (p<0.001) as well as migration and heredity (p<0.05). Discriminative analysis (rc) confirmed group difference in neuroticism 0.95541, F=38.321 with significance factor of p<0.001. EPQ test in parasuicidal subjects shows high level of neuroticism and psychoticism while controls show extroversion and conformism. Canonical Fcn = 0.6634, rc = 0.771, df = 4 χ 2 = 85.73, p<0.001. P.I.E. clearly differentiated parasuicidal group from adolescent, control group: Hi quadrant test χ 2 = 101.361 and statistical significance p<0.001. Results show: I. suicide: n=7 (7.7%), parasuicide: n=84 (43.6%) and maturation: n= 89 (48.9%). Conclusion: Representation of parasuicidal behaviour was found in both groups of examinees, but the forms are more represented in parasuicide. Sociodemographic difference between the examined groups was proved, and stress, personal and emotional structures of parasuicide were confirmed by discrimination analysis. Auto-destructivity shows even quicker forms of destruction and longer forms of self-destruction. © Medicinska naklada - Zagreb, Croatia.

The aim of this study was the detection of helicobacter pylori (HP) infection and estimation of this infection relationship with age, gender, blood groups and Rhesus factor, as well as the assessment of the accuracy of the method. A total of 227 patients with gastritis were examined. Blood ABO groups and Rh positivity were determined using standard tests. Infection by HP was proved by 14C-urea breath test and gastric biopsy. Patients were aged 20-81 years (X=51.7 years) and the presence of HP was not related to the age (P >0.05). From the total number of patients, 25/69 males and 68/158 females were HP positive. There was no significant difference between genders and HP infection (P>0.05). From the 227 investigated patients, 69 (30%) belonged to blood group O, 96 (42%) to A, 40 (18%) to B and 22 (10%) to AB. HP was detected in 27/69 patients with blood group O, 45/96 patients with blood group A, 16/40 patients with blood group B and 5/22 patients with blood group AB. There was no statistically significant difference (P>0.05) in the incidence of HP infection between these groups (proving that HP infection did not depend upon the blood groups). Also, there was no significant correlation between the presence of particular blood group in HP + patients related to the reported frequency of the blood groups in Serbian population (0- 38%, A-42%, B-15%, AB-5%). HP was found in 16/36 Rh- and in 77/191 Rh+ patients without statistical difference (P>0.05). Also, there was no significant correlation of the presence of the Rh factor in the HP positive patients to the frequency of the Rh factor in the Serbian population (84% Rh+ and 16% Rh-). The basic value of the HP+ test was slightly, but not significantly lower in comparison to the HP- patients (P>0.05). On the contrary, test values showed a highly significant difference (P<0.01) in HP+ and HP- patients. In conclusion, in adults HP infection does not depend upon the patient's age, gender, blood group type or Rh factor. In clinical terms, there were 93 true positive (TP), 129 true negative (TN), 5 false negative (FN) and 0 false positive (FP) patients. Sensitivity of the method was 94.9%, specificity 100%, positive predictive value 100%, negative predictive value 96.3% and accuracy 97.8%.

The aim of this study was to provide a comprehensive meta-analytic review of the reliability of the Hamilton Rating Scale for Depression (HRSD) for the period 1960-2008, taking into consideration all three types of reliability: internal consistency, inter-rater, and test-retest reliability. This is the first such meta-analytic study of a clinician-administered psychiatric scale. A thorough literature search was conducted using MEDLINE and PsycINFO. The total number of collected articles was 5548, of which 409 reported one or more reliability coefficients. The effect size was obtained by the z-transformation of reliability coefficients. The meta-analysis was performed separately for internal consistency, inter-rater and test-retest reliability. A pooled mean for alpha coefficient in random effects model was 0.789 (95%CI 0.766-0.810). The meta-regression analysis revealed that higher alpha coefficients were associated with higher variability of the HRSD total scores. With regard to inter-rater reliability, pooled means in random effects model were 0.937 (95%CI 0.914-0.954) for the intraclass correlation coefficient, 0.81 (95%CI 0.72-0.88) for the kappa coefficient, 0.94 (95%CI 0.90-0.97) for the Pearson correlation coefficient, and 0.91 (95%CI 0.78-0.96) for the Spearman rank correlation coefficient. A meta-regression analysis showed positive association between inter-rater reliability and publication year. Test-retest reliability of HRSD ranged between 0.65 and 0.98 and generally decreased with extending the interval between two measurements (Spearman r between the duration of interval and test-retest reliability figures = -0.74). Results suggest that HRSD provides a reliable assessment of depression. Figures indicate good overall levels of internal consistency, inter-rater and test-retest reliability, but some HRSD items (e.g., "loss of insight") do not appear to possess a satisfactory reliability. © 2010 Elsevier Ltd.

The aim of this study was to provide a comprehensive meta-analytic review of the reliability of the Hamilton Rating Scale for Depression (HRSD) for the period 1960-2008, taking into consideration all three types of reliability: internal consistency, inter-rater, and test-retest reliability. This is the first such meta-analytic study of a clinician-administered psychiatric scale. A thorough literature search was conducted using MEDLINE and PsycINFO. The total number of collected articles was 5548, of which 409 reported one or more reliability coefficients. The effect size was obtained by the z-transformation of reliability coefficients. The meta-analysis was performed separately for internal consistency, inter-rater and test-retest reliability. A pooled mean for alpha coefficient in random effects model was 0.789 (95%CI 0.766-0.810). The meta-regression analysis revealed that higher alpha coefficients were associated with higher variability of the HRSD total scores. With regard to inter-rater reliability, pooled means in random effects model were 0.937 (95%CI 0.914-0.954) for the intraclass correlation coefficient, 0.81 (95%CI 0.72-0.88) for the kappa coefficient, 0.94 (95%CI 0.90-0.97) for the Pearson correlation coefficient, and 0.91 (95%CI 0.78-0.96) for the Spearman rank correlation coefficient. A meta-regression analysis showed positive association between inter-rater reliability and publication year. Test-retest reliability of HRSD ranged between 0.65 and 0.98 and generally decreased with extending the interval between two measurements (Spearman r between the duration of interval and test-retest reliability figures = -0.74). Results suggest that HRSD provides a reliable assessment of depression. Figures indicate good overall levels of internal consistency, inter-rater and test-retest reliability, but some HRSD items (e.g., "loss of insight") do not appear to possess a satisfactory reliability. © 2010 Elsevier Ltd.

In this study we aimed to define relevant prognostic predictors for the outcome of surgical treatment of ruptured abdominal aortic aneurysms. The study included 406 consecutive patients treated between January 1991 and December 2003. There were 337 (83%) male and 69 (17%) female patients aged 67 ± 7.5 years. Fourteen (3.5%) patients had aortocaval fistula whereas 4 (0.98%) had primary aortorenteric fistula caused by aneurysm rupture into the inferior vena cava or duodenum. Reconstruction included interposition of a tube graft (215-53%), aortobiiliac bypass (134-33%), and aortobifemoral bypass (58-14.3%). Findings on admission that significantly correlated with both intraoperative (13.5%) and total operative mortality (48.3%) were systolic blood pressure <95 mmHg, low diuresis, unconsciousness, cardiac arrest, leukocytes >14 × 109/L, hematocrit <0.29%, hemoglobin <100 g/L, urea> 11 mmol/L, and creatinine >180 μmol/L. Intraoperative determinants of increased mortality were aortic cross-clamping time >47 min, duration of surgery >200 min, intraoperative blood loss >3500 mL, diuresis <400 mL, arterial systolic pressure <97.5 mmHg, and the need for aortobifemoral bypass. Respiratory complications and multisystem organ failure were significantly associated with lethal outcome in the postoperative period. Surgical treatment of ruptured abdominal aortic aneurysm was life-saving in 51.7% of patients. Variables significantly associated with mortality were unconsciousness, low systolic blood pressure, cardiac arrest, low diuresis, high urea and creatinine levels, signs of blood loss, and the need for aortobifemoral reconstruction. Short aortic cross-clamping and the total operation time, low intraoperative blood loss, and well-controlled diuresis and arterial pressure during surgery have improved survival. Therapeutic efforts should concentrate on intraoperative factors that are possible to correct, leading to better survival of these patients. © Annals of Vascular Surgery Inc.