Browsing by Author "Gledovic, Z. (6603289215)"

Purpose: To describe the pattern of bladder cancer mortality in the Beograd region, and to establish some relationships with cigarette smoking. Materials and methods: Mortality rates of bladder cancer in the Beograd population were analysed according to the official data from the Municipal Institute of Statistics in Beograd during the period 1975-1994. Age-standardization of death rates was done by the direct method, using the world population as a standard. As a significance test for linear regression coefficient in time trend analysis of mortality, Fisher's test was used. Results: During the study period the average annual standardized mortality rates from bladder cancer were 4.82 per 100,000 population (95% Confidence Interval - CI 4.11-5.53) in males and 1.52 per 100,000 population (95% CI 1.12-1.92) in females. Significantly increasing trends of the rates were observed in males (y = 2.414 + 0.229x, p <0.01), but not in females (y = 1.259 + 0.025x, p >0.05). The greatest increase in age-specific rates in males was observed in the age group of 70 and more years (y = 25.473 + 3.633x, p <0.01). In females, all age-specific rates except for the group 50-59 years showed significantly increasing tendency. The increasing tendency of bladder cancer mortality is followed by the rise of per capita cigarette consumption among the Beograd population. Conclusion: Further studies are needed for the explanation of the irregularities in the age-specific rates.

Purpose: To describe the pattern of bladder cancer mortality in the Beograd region, and to establish some relationships with cigarette smoking. Materials and methods: Mortality rates of bladder cancer in the Beograd population were analysed according to the official data from the Municipal Institute of Statistics in Beograd during the period 1975-1994. Age-standardization of death rates was done by the direct method, using the world population as a standard. As a significance test for linear regression coefficient in time trend analysis of mortality, Fisher's test was used. Results: During the study period the average annual standardized mortality rates from bladder cancer were 4.82 per 100,000 population (95% Confidence Interval - CI 4.11-5.53) in males and 1.52 per 100,000 population (95% CI 1.12-1.92) in females. Significantly increasing trends of the rates were observed in males (y = 2.414 + 0.229x, p <0.01), but not in females (y = 1.259 + 0.025x, p >0.05). The greatest increase in age-specific rates in males was observed in the age group of 70 and more years (y = 25.473 + 3.633x, p <0.01). In females, all age-specific rates except for the group 50-59 years showed significantly increasing tendency. The increasing tendency of bladder cancer mortality is followed by the rise of per capita cigarette consumption among the Beograd population. Conclusion: Further studies are needed for the explanation of the irregularities in the age-specific rates.

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[No abstract available]

Purpose: To define demographic characteristics of patients with laryngeal cancer in central Serbia, and to investigate possible relationships between their socioeconomical status and the appearance of laryngeal cancer. Methods: 100 patients (cases) with histologically verified laryngeal cancer were investigated. The control group consisted of 100 patients (controls) having no cancer. A questionnaire was filled in by both cases and controls and comparison between the groups was carried out by individual matching of demographic characteristics and socioeconomical status. Results: 91 % of the cases and controls were male (mean age 60 years). Most of the cases had lower educational level and poorer socioeconomical status compared to controls, whilst no difference was found between the 2 groups concerning their living in urban or rural environment. Conclusion: It was not possible to correlate urban environment (air pollution) as risk factor. People of lower educational level and poor socioeconomical status had increased risk of getting laryngeal cancer. © 2010 Zerbinis Medical Publications.

Purpose: To define demographic characteristics of patients with laryngeal cancer in central Serbia, and to investigate possible relationships between their socioeconomical status and the appearance of laryngeal cancer. Methods: 100 patients (cases) with histologically verified laryngeal cancer were investigated. The control group consisted of 100 patients (controls) having no cancer. A questionnaire was filled in by both cases and controls and comparison between the groups was carried out by individual matching of demographic characteristics and socioeconomical status. Results: 91 % of the cases and controls were male (mean age 60 years). Most of the cases had lower educational level and poorer socioeconomical status compared to controls, whilst no difference was found between the 2 groups concerning their living in urban or rural environment. Conclusion: It was not possible to correlate urban environment (air pollution) as risk factor. People of lower educational level and poor socioeconomical status had increased risk of getting laryngeal cancer. © 2010 Zerbinis Medical Publications.

The study comprised all 113 clinically and histologically confirmed cases of Hodgkin's disease aged 15-39 years who were treated at the Department of Hematology of the Faculty of Medicine in Belgrade from January, 1 to June, 30,1987. For each patient, two individually matched controls were selected. Neighbourhood controls were the first neighbours of he same sex, age, and residence history. Hospital controls consisted of accindentally injuered individuals, and they were matched in terms of sex, age, place of residence, and educational level. Comparison of cases and controls revealed that removal of the lymphoid tissue (either tonsils or appendix) did not affect the risk of developing Hodgkin's disease in any way. An association found by some previous studies has been explained by the confounding effect of socioeconomic status. © 1991 Gustav Fischer.

An estimated number of HIV infected individuals in Yugoslavia might be about 3000. I.v. drug users are by far the most affected population group. Prevalence of HIV seropositivity among imprisoned drug users in Belgrade approaches 50%. An effective control of unvoluntary homosexual contacts in prisons is not feasible. Having in mind a moral obligation of the society to preserve the health of its confined members, we advocate the right of (voluntary or on request screened) HIV seronegative individuals to chose to share the cell with inmates shown to be HIV seronegative as well.

An estimated number of HIV infected individuals in Yugoslavia might be about 3000. I.v. drug users are by far the most affected population group. Prevalence of HIV seropositivity among imprisoned drug users in Belgrade approaches 50%. An effective control of unvoluntary homosexual contacts in prisons is not feasible. Having in mind a moral obligation of the society to preserve the health of its confined members, we advocate the right of (voluntary or on request screened) HIV seronegative individuals to chose to share the cell with inmates shown to be HIV seronegative as well.

Aim. To analyse mortality trends of malignant digestive tract tumours. Material and methods. Population of Belgrade [Yugoslavia] in the period 1975-1997. Mortality rates were standardized by direct method using world population as the standard. For time series, exponential trends were calculated by the use of three-year moving average rates. Results. In males, the highest mortality rate was for stomach cancer - 14.6 per 100,000 [average for the period 1975-1997], followed by cancer of liver and cancer of colon-8.4/100,000, cancer of rectum - 8.1/100,000, cancer of pancreas 7.3/100,000, oesophageal cancer-2.8/100,000 and gallbladder cancer-2.0/100,000. In males, upward mortality trends for carcinomas of colon, rectum, pancreas, oesophagus, gallbladder and bile ducts were observed. The mortality rates series for stomach cancer and liver cancer did not fit any usual trend function. In females, the highest mortality rate was also for stomach cancer 7.7 per 100,000, then for cancer of colon-6.0/100,000, cancer of rectum-5.3/100,000, cancer of liver - 4.4/100,000, cancer of pancreas-4.4/100,000, gallbladder cancer 3.4/100,000 and oesophageal cancer - 0.8/100,000. In females, upward mortality trends were observed for colon and rectal cancer, cancer of pancreas, and gallbladder and bile duct cancer. Downward mortality trends were present for stomach cancer and liver cancer. Mortality rates series for oesophageal cancer did not fit any usual trend function. Conclusions. In the majority of digestive tracts cancers, an upward mortality trend was observed which is in keeping with the mortality trends of these malignant tumours in many other countries.

The aim of the study was to examine recent lung cancer mortality trends in Montenegro in the period 1976-2000, with special emphasis on correlation with tobacco consumption. A population-based study analysing lung cancer mortality in Montenegro in the period 1976-2000 was carried out Mortality rates were adjusted by direct method. A cohort analysis of age-specific death rates was performed. The analysis of tobacco consumption (cigarettes consumption per capita) was based on the official data for the period 1965-1990. Linear regression coefficients in a time trends analysis of mortality rates and tobacco consumption were assessed using Fisher's test The highest average standardized lung cancer mortality rates in Montenegro increased in each successive five-year period for both sexes from 1976 to 2000, with highest values in the last five years (1996-2000). In males the death rate has almost doubled, and in females it was nearly three-fold higher. In the cohort analysis of age-specific death rates, all age groups in the birth cohort born before 1911 had a higher lung cancer mortality risk than those in the birth cohort comprising those born between 1912 and 1931. The rates showed an increasing tendency in all age groups irrespective of sex, except in males in the 25-44 age group. The time analysis of lung cancer mortality rates for the period 1976-2000, revealed annual changes of 3% for males and 6.6% for females, respectively. During the period observed the consumption of cigarettes increased by 98.2% (from 1.064 kg per capita in 1965 to 2.109 kg per capita in 1990). The significant increasing tendency in cigarette consumption was registered (y = 1.10 + 0.05x, P = 0.001). A significant correlation between lung cancer mortality rates and cigarette consumption is also observed (r = 0.427, P = 0.037). Smoking trends up to the 1990s in Montenegro, indicate that one can expect lung cancer mortality rates to continue to increase in males but even more so in females. © 2003 Lippincott Williams & Wilkins.

The aim of the study was to examine recent lung cancer mortality trends in Montenegro in the period 1976-2000, with special emphasis on correlation with tobacco consumption. A population-based study analysing lung cancer mortality in Montenegro in the period 1976-2000 was carried out Mortality rates were adjusted by direct method. A cohort analysis of age-specific death rates was performed. The analysis of tobacco consumption (cigarettes consumption per capita) was based on the official data for the period 1965-1990. Linear regression coefficients in a time trends analysis of mortality rates and tobacco consumption were assessed using Fisher's test The highest average standardized lung cancer mortality rates in Montenegro increased in each successive five-year period for both sexes from 1976 to 2000, with highest values in the last five years (1996-2000). In males the death rate has almost doubled, and in females it was nearly three-fold higher. In the cohort analysis of age-specific death rates, all age groups in the birth cohort born before 1911 had a higher lung cancer mortality risk than those in the birth cohort comprising those born between 1912 and 1931. The rates showed an increasing tendency in all age groups irrespective of sex, except in males in the 25-44 age group. The time analysis of lung cancer mortality rates for the period 1976-2000, revealed annual changes of 3% for males and 6.6% for females, respectively. During the period observed the consumption of cigarettes increased by 98.2% (from 1.064 kg per capita in 1965 to 2.109 kg per capita in 1990). The significant increasing tendency in cigarette consumption was registered (y = 1.10 + 0.05x, P = 0.001). A significant correlation between lung cancer mortality rates and cigarette consumption is also observed (r = 0.427, P = 0.037). Smoking trends up to the 1990s in Montenegro, indicate that one can expect lung cancer mortality rates to continue to increase in males but even more so in females. © 2003 Lippincott Williams & Wilkins.