Browsing by Author "Cvjetic, Olivera (6504232805)"

A case of Langerhans cell histiocytosis (LCH) in a 45-year old female with ulcerative lesions of the skin and mucous membranes, is reported. Initial changes were noted on the genital region 11 years earlier but had remained undiagnosed until now. The observation of Birbeck granules in lesional cells by electron microscope led to a definitive diagnosis. Results of investigations were used to classify the case in accordance with 'LCH stratification related to extent of the disease' of the Histiocyte Society. Systemic and local treatments with corticosteroids proved to be effective in controlling the symptoms.