Browsing by Author "Bukumiric, Z. (36600111200)"

– OBJECTIVE: Every year, melanoma claims over 20,000 lives in Europe. In Montenegro, as in Europe, numerous campaigns have been initiated to raise public awareness about the importance of melanoma prevention and its early detection. Thus, accompanying current diagnostic and therapeutic protocols, new methods of melanoma diagnosis and treatment have been implemented. Studying the trend enables the identification of the groups most burdened by mortality and assesses whether there has been a change in trends based on interventions aiming to reduce mortality. The objective of this study is to evaluate the mortality trend from cutaneous melanoma in Montenegro for the period 1990-2018. MATERIALS AND METHODS: We have utilized national data on the causes of death from melanoma, code 179 from the ninth and C43 from the tenth revision of the International Classification of Diseases, categorized by gender and age groups. The study utilized various regression techniques, including Joinpoint regression in the Joinpoint Program, Poisson regression, and linear regression in the SPSS 26th Program, to describe the trend. RESULTS: In Montenegro, during the period from 1990 to 2018, a total of 281 individuals died (51.6% male and 48.4% female). This ranks as the 13th leading cancer in terms of mortality among all cancers. The average age-standardized rate was 1.1 deaths per 100,000 (1.2 for males and 1.0 for females). The number of death cases has been increasing on average by 3.3% annually [average annual percentage change (AAPC) (95% CI) = 3.3 (1.7-4.9); p<0.001] on an overall level and by 5.4% annually among males [AAPC (95% CI) = 5.4 (3.6-7.3); p<0.001] due to the rises in the age groups 55-64 years and 65-74 years with an average annual percent change of respectively 3.2% [AAPC (95% CI) = 3.2 (0.8-5.8); p=0.012] and 5.4% [AAPC (95% CI) = 5.4 (2.7-8.1); p<0.001] overall level, and 4.8% [AAPC (95% CI) = 4.8 (2.4-7.3); p<0.001] and 7.5% [AAPC (95% CI) = 7.5 (4.9-10.2); p<0.001] among males. For females, an increase of 1.1% was recorded, which was not statistically significant [AAPC (95% CI) = 1.1 (-0.8-3.0); p=0.255]. Furthermore, there was a noted increase in the rates at an overall level [β (95% CI) = 0.027 (0.008-0.046); p=0.007] and in the age group 65-74 years [β (95% CI) = 0.249 (0.090-0.407); p=0.003], as well as among males at an overall level [β (95% CI) = 0.052 (0.025-0.079); p<0.001] and for age groups 45-54 years [β (95% CI) = 0.102 (0.011-0.193); p=0.030] and 65-74 [β (95% CI) = 0.410 (0.144-0.676); p=0.004]. In contrast, the rates for females remained constant. The three age groups most burdened by melanoma skin cancer mortality are 65-74 years (23.5%), 55-64 years (21.7%) and 75-84 years (19.2%). CONCLUSIONS: The results of regression analyses indicate a significant rise in both the number of death cases and mortality rates overall, specifically among males in Montenegro. In females, however, the increase in the number of death cases and rates is not statistically significant. Preventive campaign activities should be redirected towards the most vulnerable groups in terms of mortality, namely males and the elderly population. © 2024 Verduci Editore s.r.l. All rights reserved.

Purpose: SCI are one of the leading causes of disabilities around the world. Length of stay in patients with spinal cord injury depends on many medical and non-medical factors, especially of health-care system and social environment. Material and Method: The study included 529 patients with spinal cord injuries admitted in Clinic for rehabilitation Dr M. Zotovic, Belgrade, Serbia, from January 2000 to December 2009. The factors influencing length of stay in our study were: age, gender, neurological level and completeness of injury, etiology of injury, methods of treatment, secondary complications and associated injuries. Length of stay in this study was defined from the date of admission to the date of discharge from rehabilitation. Results: Median length of rehabilitation is 134 days (range, 28.0-533.0). The average age of survey respondents was 46.1±16.8 years. In this study 382 (72.2%) of patients were male and 147 (27.8%) were female. There were 180 (34.0%) tetraplegic and 349 (66%) paraplegic patients. In the multivariate Cox regression model, statistically significant predictors of length of stay were: neurological level of injury (p=0.014), completeness of the lesion (p=0.048), ASIA scale (p<0.001), age (p=0.043), urinary tract infection (p<0.001) and spasticity (p=0.042) as complications during rehabilitation. Conclusion: Reducing the length of stay would significantly decrease the overall financial costs for patients with spinal cord injury. Construction of the specialized centers for rehabilitation of patients with spinal cord injury and better coordination between primary care and rehabilitation centers would contribute to it. © Georg Thieme Verlag KG Stuttgart New York 2015.

Purpose: SCI are one of the leading causes of disabilities around the world. Length of stay in patients with spinal cord injury depends on many medical and non-medical factors, especially of health-care system and social environment. Material and Method: The study included 529 patients with spinal cord injuries admitted in Clinic for rehabilitation Dr M. Zotovic, Belgrade, Serbia, from January 2000 to December 2009. The factors influencing length of stay in our study were: age, gender, neurological level and completeness of injury, etiology of injury, methods of treatment, secondary complications and associated injuries. Length of stay in this study was defined from the date of admission to the date of discharge from rehabilitation. Results: Median length of rehabilitation is 134 days (range, 28.0-533.0). The average age of survey respondents was 46.1±16.8 years. In this study 382 (72.2%) of patients were male and 147 (27.8%) were female. There were 180 (34.0%) tetraplegic and 349 (66%) paraplegic patients. In the multivariate Cox regression model, statistically significant predictors of length of stay were: neurological level of injury (p=0.014), completeness of the lesion (p=0.048), ASIA scale (p<0.001), age (p=0.043), urinary tract infection (p<0.001) and spasticity (p=0.042) as complications during rehabilitation. Conclusion: Reducing the length of stay would significantly decrease the overall financial costs for patients with spinal cord injury. Construction of the specialized centers for rehabilitation of patients with spinal cord injury and better coordination between primary care and rehabilitation centers would contribute to it. © Georg Thieme Verlag KG Stuttgart New York 2015.