Browsing by Author "Boboš, Marina (59782431600)"

Introduction/Objective Despite frequent side effects such as hypotension, spinal anesthesia (SA) is still one of the best anesthetic methods for elective cesarean section (CS). Intermittent, oscillometric, non-invasive blood pressure monitoring (NIBP) frequently leads to missed hypotensive episodes. The objective was to compare continuous non-invasive arterial pressure (CNAP) monitoring with NIBP in the terms of efficiency to detect hypotension. Methods In this study, we compared CNAP and NIBP monitoring for hypotension detection in 76 patients divided into two groups of 38 patients treated with ephedrine (E) or phenylephrine (P), during three-minute intervals, starting from SA, by the end of the surgery. Results In E group, significantly lower mean systolic blood pressure (SBP) values with CNAP compared with NIBP (p = 0.008) was detected. By monitoring CNAP, we detected 31 (81.6%) hypotensive patients in E group and significantly lower number, 20 (52.6%), with NIBP (p = 0.001), while in P group CNAP detected 34 patients (89.5%) and NIBP only 18 (47.3%), p = 0.001. By monitoring CNAP, we detected significantly higher number of hypotensive intervals in E and P groups (p < 0.001). Umbilical vein pH was lower within hypotensive compared with normotensive patients in E and P groups, with CNAP and NIBP, respectively (p < 0.001, p = 0.027 in E, and p = 0.009, p < 0.001, in P group). Conclusion CNAP is more efficient in hypotension detection for CS during SA, which allows faster treatment of hypotension, thus improving fetal and maternal outcome. © 2021, Serbia Medical Society. All rights reserved.

Possible immune system interactions due to vaccination and drugs used in general anesthesia represent a dilemma for pediatric anesthesiologists in everyday practice. Immunosuppression caused by anesthesia and surgical trauma can affect the immunization process and cause-specific unwanted reactions. On the other hand, side effects due to vaccination can confuse clinicians in the immediate postoperative course. Both the nature of the vaccine and the type of surgery determines the delay period of elective surgical intervention. This current topic aims to present the scientific facts about the complex interactions between vaccination, immunization, general anesthesia, and surgical trauma and to provide recommendations for preoperative preparation. © 2023, Serbia Medical Society. All rights reserved.