Browsing by Author "Baralic, I. (24400806100)"

Objectives: Secretory IgA is predominant immunoglobulin in secretions of the mucosal immune system. Low concentration of salivary IgA is associated with a higher risk of respiratory tract infections episodes in athletes during the training season. The purpose of this study was to determine whether orange-flavored whey based drink has beneficial effect on level of IgA in saliva after the training. Methods: Twenty healthy, young karate players participated in this study. They were divided into two groups. One group rinsed a mouth with 20 ml of liquid whey, two times in 30-min period: 15 and 30 min after training. Second group rinsed a mouth with 20 ml of whey based orange flavored soft drink, at the same time. Saliva was collected before the training, just after the training and after application of fluids. Results: We observed decrease in salivary flow after physical activity. The salivary flow was higher after the application of flavored drink compared to salivary flow after the application of whey. The absolute concentration of slgA and slgA secretion rate decreased just after exercise compared to pre exercise values. Application of whey elevated slgA levels on day 1, while application of flavored drink caused increasing in slgA levels on day 3. In all other cases slgA level was decreasing even after applied stimuli. Conclusions: The exercise induces decreasing in salivary flow, slgA absolute concentration and slgA secretion rate. Application of fluid whey and flavored whey-based drink elevated salivary flow, but had little effect on absolute concentration of slgA and slgA secretion rate in young karate players.

Objectives: Secretory IgA is predominant immunoglobulin in secretions of the mucosal immune system. Low concentration of salivary IgA is associated with a higher risk of respiratory tract infections episodes in athletes during the training season. The purpose of this study was to determine whether orange-flavored whey based drink has beneficial effect on level of IgA in saliva after the training. Methods: Twenty healthy, young karate players participated in this study. They were divided into two groups. One group rinsed a mouth with 20 ml of liquid whey, two times in 30-min period: 15 and 30 min after training. Second group rinsed a mouth with 20 ml of whey based orange flavored soft drink, at the same time. Saliva was collected before the training, just after the training and after application of fluids. Results: We observed decrease in salivary flow after physical activity. The salivary flow was higher after the application of flavored drink compared to salivary flow after the application of whey. The absolute concentration of slgA and slgA secretion rate decreased just after exercise compared to pre exercise values. Application of whey elevated slgA levels on day 1, while application of flavored drink caused increasing in slgA levels on day 3. In all other cases slgA level was decreasing even after applied stimuli. Conclusions: The exercise induces decreasing in salivary flow, slgA absolute concentration and slgA secretion rate. Application of fluid whey and flavored whey-based drink elevated salivary flow, but had little effect on absolute concentration of slgA and slgA secretion rate in young karate players.

Purpose: To determine survivin expression patterns in Wilms tumor (WT) and compare it with the expression in normal renal tissue. Also, to analyse cytoplasmic and nuclear survivin expression in relation to histological type, prognostic group and tumor stage. Methods: Immunohistochemical expression of survivin was analysed in 59 cases of primary WT and in 10 normal kidney specimens, taken from the same patients, but distant from the tumor. Results: 51 out of 59 cases of WT (86.44%) showed decreased cytoplasmic survivin expression and 4 out of 59 cases of WT (6.78%) showed nuclear overexpression of survivin. There was statistically significant difference in the frequency of decreased cytoplasmic expression of survivin in individual components of WT (p=0.005). Decreased cytoplasmic expression of survivin in epithelial, blastemal and stromal component was found significantly more often in low stage WT compared to high stage WT (Fisher exact test, p=0.0002, p=0.002, p=0.002, respectively). There was no statistically significant difference in the frequency of survivin nuclear overexpression between different stages of WT (Fisher exact test, p=0.564), histological types (Fisher exact test, p=0.915), or between different prognostic groups (Fisher exact test, p=1). Conclusion: Decreased survivin cytoplasmic expression or nuclear overexpression may be related to favorable prognosis of WT. © 2012 Zerbinis Medical Publications.

Purpose: To determine survivin expression patterns in Wilms tumor (WT) and compare it with the expression in normal renal tissue. Also, to analyse cytoplasmic and nuclear survivin expression in relation to histological type, prognostic group and tumor stage. Methods: Immunohistochemical expression of survivin was analysed in 59 cases of primary WT and in 10 normal kidney specimens, taken from the same patients, but distant from the tumor. Results: 51 out of 59 cases of WT (86.44%) showed decreased cytoplasmic survivin expression and 4 out of 59 cases of WT (6.78%) showed nuclear overexpression of survivin. There was statistically significant difference in the frequency of decreased cytoplasmic expression of survivin in individual components of WT (p=0.005). Decreased cytoplasmic expression of survivin in epithelial, blastemal and stromal component was found significantly more often in low stage WT compared to high stage WT (Fisher exact test, p=0.0002, p=0.002, p=0.002, respectively). There was no statistically significant difference in the frequency of survivin nuclear overexpression between different stages of WT (Fisher exact test, p=0.564), histological types (Fisher exact test, p=0.915), or between different prognostic groups (Fisher exact test, p=1). Conclusion: Decreased survivin cytoplasmic expression or nuclear overexpression may be related to favorable prognosis of WT. © 2012 Zerbinis Medical Publications.