Browsing by Author "Baletic, Nenad (24398182100)"

Any endoscopic diagnostic procedure that iscapable of giving exact information on laryngeal lesions without damaging the tissue has essential advantages over standard biopsy. Tissue autofluorescence is deWned as a natural ability of tissue to fluoresce when exposed to a certain light wavelength. This feature is a consequence of the presence of fluorophores in the tissues, which are activated by a narrow wavelength range. However, due to their biochemical and biophysical characteristics, laryngeal precancerosis and cancer do not fluoresce when exposed to blue light. In the present study, we used Pentax's System of Autofluorescent Endoscopy (SAFE 1000) to detect auto-fluorescence disturbances from laryngeal mucosa. Diagnostic parameters (sensitivity and specificity) of the microlaryngoscopy (MLS) and SAFE 1000 in the diagnosis of laryngeal precancerosis and carcinoma were compared and discussed. We have found that SAFE had a better sensitivity with regard to mentioned laryngeal pathology, but MLS had better specificity than SAFE. The overall diagnostic sensitivity in the diagnostics of laryngeal atypical hyperplasia and cancer with SAFE was 89%, as opposed to 73% with MLS. Diagnostic specificity of SAFE for all cases of laryngeal carcinomas and atypical hyperplasia was 78%. The specificity of MLS in diagnostics of laryngeal carcinomas cases was 98%, while that for cases of atypical hyperplasia was 100%. Many other conditions that have impact on autofluorescent features of laryngeal mucosa were also discussed. © Springer-Verlag 2009.

Glassblowers are exposed to numerous physical and chemical noxious factors at their workplace. Mucosal layer of upper aerodigestive tract (nose, oral cavity, pharynx and larynx) is particularly vulnerable to the influence of these factors. Inhalation of hot gases, dust particles, and oral contact with glassblower's pipe are the most important factors that can cause chronic inflammation of the upper respiratory tract. The aim of this study was to examine the prevalence of chronic laryngitis in the group of glassblowers and control group of workers and to examine whether the observed differences depend on the membership in these two groups, on the duration of exposure, or on both factors. The results of the study show significantly higher prevalence of chronic laryngitis among glassblowers than among control group of workers employed in the same plant. On the other hand, the duration of exposure was not statistically significant factor for chronic laryngitis. The exposure to risk factors on the working place represents an independent risk factor for the occurrence of chronic laryngitis among glassblowers, when adjusted for other possible confounders, such as age, years of service, smoking habits and alcohol consumption.

Glassblowers are exposed to numerous physical and chemical noxious factors at their workplace. Mucosal layer of upper aerodigestive tract (nose, oral cavity, pharynx and larynx) is particularly vulnerable to the influence of these factors. Inhalation of hot gases, dust particles, and oral contact with glassblower's pipe are the most important factors that can cause chronic inflammation of the upper respiratory tract. The aim of this study was to examine the prevalence of chronic laryngitis in the group of glassblowers and control group of workers and to examine whether the observed differences depend on the membership in these two groups, on the duration of exposure, or on both factors. The results of the study show significantly higher prevalence of chronic laryngitis among glassblowers than among control group of workers employed in the same plant. On the other hand, the duration of exposure was not statistically significant factor for chronic laryngitis. The exposure to risk factors on the working place represents an independent risk factor for the occurrence of chronic laryngitis among glassblowers, when adjusted for other possible confounders, such as age, years of service, smoking habits and alcohol consumption.