Browsing by Author "Adanja, B.J. (7003966459)"

Study objective - To determine trends in cardiovascular disease mortality. Design - This was a descriptive study analysing mortality data. Setting - Belgrade, Yugoslavia. Participants - The population of Belgrade in the age group 30-69 years was studied (about 760 000 inhabitants). Measurements - Mortality rates were standardised directly using those of the 'European population' as the standard, and regression analysis was undertaken. Main results - Between 1975 and 1989 'all causes' mortality increased by 27% (95% confidence interval 18.5, 35.9) in men and by 19% (11.6, 27.1) in women. The increase in cardiovascular disease mortality was 7% (1.7, 11.5) for men and 4% (0.2, 7.8) for women. Mortality from ischaemic heart disease fell in both sexes by 32% (23.0, 41.0), but mortality from other heart diseases rose by 31% (22.0, 40.2) in men and 25% (16.2, 33.0) in women. In men the death rate for cerebrovascular disease increased by 37% (27.8, 46.8), but in women the rate fell by 0.4% (-0.8, 1.6). Mortality from the observed causes of death was higher in men than in women. Conclusion - Cardiovascular mortality trends in Belgrade are similar to those in most eastern European countries. If the distribution of cigarette smoking and a 'rich' diet in the Belgrade population is taken into account, a considerable decline in cardiovascular mortality trends cannot be expected in the near future.

The case-control study was conducted in Belgrade (Yugoslavia) during the period 1994-1998. The objective of the study was to investigate factors related to the occurrence of multiple myeloma (MM). The study group consisted of 100 newly diagnosed MM patients and the same number of matched hospital controls. In the analysis conditional univariate and multivariate logistic regression were applied. According to multivariate analysis the following factors were significantly related to MM: smoking ≥25 cigarettes per day (Odds ratio- OR=6.7, 95% confidence interval-95% CI=1.3-34.3); having more than two brothers (OR=2.7, 95% CI=1.3-5.3), rheumatoid arthritis in personal history (OR=4.2, 95% CI=1.2-14.8), and frequent (4-7 times per week vs. lower frequency) consumption of yogurt (OR=3.1 95% CI=1.6-6.0) and vegetables (OR=0.4, 95% CI=0.1-1.0).

[No abstract available]

The aim of this study was to assess the risk factors for basal cell carcinoma (BCC). A case-control study, carried out in two towns in Yugoslavia, comprised 200 BCC cases and 399 controls. For statistical analysis, univariate and multivariate logistic regressions were used. The risk factors found for BCC were: freckling before the age 15, seven or more weeks per year spent at the seaside during holidays (lifetime average), outdoor work during summer-time, occupational exposure to organic and non-organic dissolvents and organophosphatic compounds, use of tar for cosmetic purposes, and previous BCC in personal history. Subjects who tended to burn and not to tan after sun exposure also showed a significantly higher risk for BCC. Brown eyes and history of acne had a protective effect. This study confirmed the role of both constitutional and environmental factors in the development of BCC.

Background: Thyroid cancer is relatively rare, but it is the most frequent cancer among malignancies of the endocrine system. To evaluate the association between thyroid cancer and potential risk factors. Material and methods: A case-control study was conducted in Central Serbia, Yugoslavia. The case group consisted of 100 newly diagnosed patients with histologically confirmed thyroid cancer. The controls (100 patients with injuries) were individually matched with cases by sex, age and place of residence. McNemar's test and conditional logistic regression were used in the analysis. Results: According to logistic regression analysis the following factors were independently related with the occurrence of thyroid cancer: diagnostic X- ray during childhood and/or youth goiter, history of residence in endemic goiter area, anemia in personal history, history of previous malignant tumors, family history of any malignant tumor, spontaneous abortion and use of oral contraceptives. Conclusion: The present study supports the hypothesis that besides other risk factors, thyroid cancer in women is affected by some reproductive and probably hormonal factors.