Browsing by Author "Adanja, B. (7003966459)"

The objective of the work was to study blood pressure and some anthropometric characteristics in children. The study design included the prevalence study at Belgrade, Serbia and Montenegro. The study comprised 1651 subjects (809 boys and 842 girls) aged 7-14 years, that is, 2.6% of all relevant population. The average levels of systolic and diastolic blood pressures (SBP and DBF) were 113.4/70.3 mmHg in boys and 114.6/71.1 mmHg in girls. High SBP was present in 4.7% of boys and in 5.3% of girls. High DBP was found in 5.6% of boys and in 4.8% of girls. According to multivariate regression analysis, in boys SBP and DBP were significantly associated with age, body mass index (BMI) and subscapular skinfold, SBP was also associated with body weight, and DBP with triceps skinfold. In girls, SBP was significantly related to BMI, suprailiac skinfold and body height, and DBP was significantly associated with BMI, suprailiac and subscapular skinfolds. The results of the present study support the opinion that BMI is a significant predictor of blood pressure in children and point out to suprailiac skinfold in girls as a possible predictor of blood pressure.

[No abstract available]

Purpose: To test some hypotheses concerning risk factors for Hodgkin's disease (HD). Material and methods: A case-control study conducted in Beograd from 1993 to 1996 enrolled 100 patients with histologically confirmed HD and 100 hospitalized non-cancer patients (controls), individually matched by sex, age (±2 years) and place of residence. A number of risk factors was evaluated, in the analysis of which the McNemar's test and univariate and multivariate logistic regression analyses were used. Results: According to multivariate analysis the following factors were significantly related to HD: white collar occupation, daily consumption of milk, cheese and fruit, use of lard for food preparation, age difference between participant and first older sibling >3 years and possession of pets. Conclusion: The results obtained support the hypothesis that, in addition to other factors, some dietary components influence the occurrence of HD.

Purpose: To test some hypotheses concerning risk factors for Hodgkin's disease (HD). Material and methods: A case-control study conducted in Beograd from 1993 to 1996 enrolled 100 patients with histologically confirmed HD and 100 hospitalized non-cancer patients (controls), individually matched by sex, age (±2 years) and place of residence. A number of risk factors was evaluated, in the analysis of which the McNemar's test and univariate and multivariate logistic regression analyses were used. Results: According to multivariate analysis the following factors were significantly related to HD: white collar occupation, daily consumption of milk, cheese and fruit, use of lard for food preparation, age difference between participant and first older sibling >3 years and possession of pets. Conclusion: The results obtained support the hypothesis that, in addition to other factors, some dietary components influence the occurrence of HD.

Conditional logistic regression analysis of case-control study data showed that the following factors were significantly related to rheumatic fever occurrence: home dampness, change of place of residence during the last 5 years, low education of mother, body weight below normal, frequent sore throat and positive family history of rheumatic fever. © 1991 Gustav Fischer.

Aim. To analyse mortality trends of malignant digestive tract tumours. Material and methods. Population of Belgrade [Yugoslavia] in the period 1975-1997. Mortality rates were standardized by direct method using world population as the standard. For time series, exponential trends were calculated by the use of three-year moving average rates. Results. In males, the highest mortality rate was for stomach cancer - 14.6 per 100,000 [average for the period 1975-1997], followed by cancer of liver and cancer of colon-8.4/100,000, cancer of rectum - 8.1/100,000, cancer of pancreas 7.3/100,000, oesophageal cancer-2.8/100,000 and gallbladder cancer-2.0/100,000. In males, upward mortality trends for carcinomas of colon, rectum, pancreas, oesophagus, gallbladder and bile ducts were observed. The mortality rates series for stomach cancer and liver cancer did not fit any usual trend function. In females, the highest mortality rate was also for stomach cancer 7.7 per 100,000, then for cancer of colon-6.0/100,000, cancer of rectum-5.3/100,000, cancer of liver - 4.4/100,000, cancer of pancreas-4.4/100,000, gallbladder cancer 3.4/100,000 and oesophageal cancer - 0.8/100,000. In females, upward mortality trends were observed for colon and rectal cancer, cancer of pancreas, and gallbladder and bile duct cancer. Downward mortality trends were present for stomach cancer and liver cancer. Mortality rates series for oesophageal cancer did not fit any usual trend function. Conclusions. In the majority of digestive tracts cancers, an upward mortality trend was observed which is in keeping with the mortality trends of these malignant tumours in many other countries.

Pancreatic cancer is characterized by high incidence and high mortality rates in developed countries and low ones in developing countries. To analyse pancreatic cancer mortality in Belgrade population and it's secular trend. Material and Methods: Age-adjusted death rates per 100,000 population were calculated separately for males and females, using the direct method of standardization and the world population as the standard. The least square method was used to fit mortality rates to different trend curves. During the period 1975-1994 increasing mortality trends for cancer of pancreas were established in Belgrade population in both sexes. The increase of mortality was parallel to the increased consumption of coffee, alcohol and tobacco. The observed trend is in agreement with the increasing mortality of pancreatic cancer registered almost everywhere in the world.

Objective. To determine the prevalence of chronic arthritis with special reference to rheumatoid arthritis. Method. A cross-sectional study was performed during the years 1990 and 1991 in a randomly selected sample of the urban population of Belgrade. Results. Out of 2184 participants, ≤ 20 yr old, surveyed by questionnaire, 756 (34.6%) reported peripheral joint complaints. Of those with complaints, 621 (82.1%) agreed to undergo detailed examination. Arthritis was diagnosed in four men (one had rheumatoid arthritis and three had spondylarthropathy with peripheral arthritis) and 11 women (three had rheumatoid arthritis, one had B27-positive polyarthritis and seven had undifferentiated chronic arthritis). The prevalence of chronic arthritis in the adult population was 0.69% (0.35% for men and 1.05% for women). The prevalence for rheumatoid arthritis was 0.18% (0.09% for men and 0.29% for women). Re-examination of 15 individuals with chronic arthritis 3 yr later showed changes in diagnosis only in those patients who at baseline examination had undifferentiated chronic arthritis. Conclusion. According to the results obtained, the urban population of Belgrade is among populations with a low prevalence of rheumatoid arthritis.

Objective. To determine the prevalence of chronic arthritis with special reference to rheumatoid arthritis. Method. A cross-sectional study was performed during the years 1990 and 1991 in a randomly selected sample of the urban population of Belgrade. Results. Out of 2184 participants, ≤ 20 yr old, surveyed by questionnaire, 756 (34.6%) reported peripheral joint complaints. Of those with complaints, 621 (82.1%) agreed to undergo detailed examination. Arthritis was diagnosed in four men (one had rheumatoid arthritis and three had spondylarthropathy with peripheral arthritis) and 11 women (three had rheumatoid arthritis, one had B27-positive polyarthritis and seven had undifferentiated chronic arthritis). The prevalence of chronic arthritis in the adult population was 0.69% (0.35% for men and 1.05% for women). The prevalence for rheumatoid arthritis was 0.18% (0.09% for men and 0.29% for women). Re-examination of 15 individuals with chronic arthritis 3 yr later showed changes in diagnosis only in those patients who at baseline examination had undifferentiated chronic arthritis. Conclusion. According to the results obtained, the urban population of Belgrade is among populations with a low prevalence of rheumatoid arthritis.

The occurrence of rheumatic fever and rheumatic heart disease in the period 1970-1979 is analysed on the basis of morbidity and mortality data. It was found that: -Rheumatic fever first attacks rate and rheumatic fever recurrent attacks rate in 1979 were by 80% and 91% lower respectively, compared with 1970 rates; - The disease became milder and the number of RF with heart involvement decreased especially in population over 19 years old; -In the ten year period mortality rate from rheumatic fever and rheumatic heart disease decreased 2.8 times; -In the age group 15-24 mortality did not decline so noticible and mortality rate in this age group is still ten times higher than the same rate in the most developed countries; -Among all defined causes of death (except accidents), in the age group 15-24, rheumatic fever and rheumatic heart disease (taken together) fell from first or second place to the eleventh or tenth place in the last years under review; -One can expect that the declining trend of morbidity and mortality from rheumatic fever and rheumatic heart disease will continue though probably slower than in the preceding period.

The occurrence of rheumatic fever and rheumatic heart disease in the period 1970-1979 is analysed on the basis of morbidity and mortality data. It was found that: -Rheumatic fever first attacks rate and rheumatic fever recurrent attacks rate in 1979 were by 80% and 91% lower respectively, compared with 1970 rates; - The disease became milder and the number of RF with heart involvement decreased especially in population over 19 years old; -In the ten year period mortality rate from rheumatic fever and rheumatic heart disease decreased 2.8 times; -In the age group 15-24 mortality did not decline so noticible and mortality rate in this age group is still ten times higher than the same rate in the most developed countries; -Among all defined causes of death (except accidents), in the age group 15-24, rheumatic fever and rheumatic heart disease (taken together) fell from first or second place to the eleventh or tenth place in the last years under review; -One can expect that the declining trend of morbidity and mortality from rheumatic fever and rheumatic heart disease will continue though probably slower than in the preceding period.

Background: Basal-cell carcinoma (BCC) is the most common type of cancer in white population. The aim of this study was to assess risk factors for BCC. Methods: Case-control study was performed in Belgrade, Yugoslavia, from February to November 1996. By the use of a questionnaire, data on suspected risk factors were obtained from one hundred BCC cases and the same number of controls, individually matched by year of birth, sex and place of residence. For statistical analysis, t test, univariate and multivariate logistic regression were used. Results: According to conditional logistic regression analysis the following factors were related to BCC: blue eyes (Odds ratio - OR=5.95, 95% confidence interval - CI = 1.10-32.13), freckling (OR = 1.08 95% CI = 0.49-2.37), sunburns (OR = 20.83 95% CI = 2.49-174.38), farming (OR = 3.04 95% CI = 0.99-9.30), outdoor sports and recreation (OR = 9.09 95% CI = 0.97-84.90), radiotherapy (OR = 6.27 95% CI = 0.99-39.65), smoking (OR = 4.79 95% CI = 1.33-17.28) and family history of any malignant tumor (OR = 6.89 95% CI = 1.27-37.21). A significantly increased risk for BCC was also seen in sun-sensitive subjects whose skin tended to burn rather than tan in the sun (OR = 3.02 95% CI = 1.24-7.34). Acne vulgaris were inversely related to BCC (OR = 0.28 95% CI = 0.09-0.83). Conclusion: Pigmentary traits and sun sensitivity of the skin confirmed their role in the occurrence of BCC. Among environmental factors sunlight exposure, radiotherapy and smoking were independent risk factors for this malignant tumor. Acne vulgaris had a protective effect on BCC.

[No abstract available]

One hundred and fourty-eight rheumatic fever patients and 444 controls matched by age, sex and place of residence, were interviewed about socio-economic and some other variables. Socio-economic factors recognized as risk factors for rheumatic fever (flat dampness, more than 2 persons per room, sleeping in bed with other person, low education of mother and undernourishment) were of lesser importance for persons with frequent sore throat in comparison to persons without frequent sore throat. According to the results obtained it seems that there is positive connection between host's propensity to clinical manifestation of throat infection and manifestation of rheumatic fever. The lesser susceptibility the more additional factors are needed for Rheumatic Fever to occur. The relative importance of socio-economic factors in rheumatic fever occurrence depends on host's susceptibility to infection.

One hundred and fourty-eight rheumatic fever patients and 444 controls matched by age, sex and place of residence, were interviewed about socio-economic and some other variables. Socio-economic factors recognized as risk factors for rheumatic fever (flat dampness, more than 2 persons per room, sleeping in bed with other person, low education of mother and undernourishment) were of lesser importance for persons with frequent sore throat in comparison to persons without frequent sore throat. According to the results obtained it seems that there is positive connection between host's propensity to clinical manifestation of throat infection and manifestation of rheumatic fever. The lesser susceptibility the more additional factors are needed for Rheumatic Fever to occur. The relative importance of socio-economic factors in rheumatic fever occurrence depends on host's susceptibility to infection.

In a case control study we evaluated the effects of socioeconomic and some other factors on the risk of Rheumatic Fever (RF) occurrence. We compared 148 patients, with RF first attack, with 444 controls individually matched to the patients for age, sex, and place of residence. The unemployment of parents was found to be the most closely related to RF, the estimated relative risk (RR) being 10.37 (95 per cent confidence limits 5.31 to 20.24). Among other socioeconomic factors, the following were found to be significantly related to RF: low education of mother, the RR being 2.58 (CL 1.38 to 4.83), change of place of residence during last 5 years, the RR being 5.00 (CL 1.52 to 7.93) and poor living conditions, that is, deteriorated condition of dwellings, the RR being 1.83 (CL 1.12 to 2.98), home dampness, with the RR of 2.48 (CL 1.34 to 4.61) and home crowding expressed as more then 2 persons per room, the RR being 1.72 (CL 1.08 to 2.72), less then 5 m2 of living space per capita, with the RR of 2.83 (CL 1.19 to 6.71) and sleeping in bed with other person, giving the RR of 1.65 (CL 1.02 to 2.66). Out of other factors observed, that were the subject matter of the study, history of frequent sore throat and family history positive on RF were found to be significantly more frequent in patients then in their controls, with corresponding RR of 2.01 (CL 1.41 to 2.89) and 2.81 (CL 1.68 to 4.69) respectively.

In a case control study we evaluated the effects of socioeconomic and some other factors on the risk of Rheumatic Fever (RF) occurrence. We compared 148 patients, with RF first attack, with 444 controls individually matched to the patients for age, sex, and place of residence. The unemployment of parents was found to be the most closely related to RF, the estimated relative risk (RR) being 10.37 (95 per cent confidence limits 5.31 to 20.24). Among other socioeconomic factors, the following were found to be significantly related to RF: low education of mother, the RR being 2.58 (CL 1.38 to 4.83), change of place of residence during last 5 years, the RR being 5.00 (CL 1.52 to 7.93) and poor living conditions, that is, deteriorated condition of dwellings, the RR being 1.83 (CL 1.12 to 2.98), home dampness, with the RR of 2.48 (CL 1.34 to 4.61) and home crowding expressed as more then 2 persons per room, the RR being 1.72 (CL 1.08 to 2.72), less then 5 m2 of living space per capita, with the RR of 2.83 (CL 1.19 to 6.71) and sleeping in bed with other person, giving the RR of 1.65 (CL 1.02 to 2.66). Out of other factors observed, that were the subject matter of the study, history of frequent sore throat and family history positive on RF were found to be significantly more frequent in patients then in their controls, with corresponding RR of 2.01 (CL 1.41 to 2.89) and 2.81 (CL 1.68 to 4.69) respectively.

During the period of 1975-1989, in the Belgrade population increasing mortality trends were established for colon and rectal cancer, cancer of the pancreas and gallbladder and bile ducts cancer, for both sexes, and for esophageal cancer in males. Stomach and liver cancer mortality decreased in females. In males, stomach cancer mortality after a prolonged steady decrease suddenly rose in the years 1988 and 1989. Mortality rates series for esophageal cancer in females and for liver cancer in males did not fit any usual trend function. © 1994 Kluwer Academic Publishers.