Chioncel, Ovidiu (12769077100)Ovidiu (12769077100)ChioncelMebazaa, Alexandre (57210091243)Alexandre (57210091243)MebazaaHarjola, Veli-Pekka (6602728533)Veli-Pekka (6602728533)HarjolaCoats, Andrew J. (35395386900)Andrew J. (35395386900)CoatsPiepoli, Massimo Francesco (7005292730)Massimo Francesco (7005292730)PiepoliCrespo-Leiro, Maria G. (35401291200)Maria G. (35401291200)Crespo-LeiroLaroche, Cecile (7102361087)Cecile (7102361087)LarocheSeferovic, Petar M. (6603594879)Petar M. (6603594879)SeferovicAnker, Stefan D. (56223993400)Stefan D. (56223993400)AnkerFerrari, Roberto (36047514600)Roberto (36047514600)FerrariRuschitzka, Frank (7003359126)Frank (7003359126)RuschitzkaLopez-Fernandez, Silvia (55604539700)Silvia (55604539700)Lopez-FernandezMiani, Daniela (6602718496)Daniela (6602718496)MianiFilippatos, Gerasimos (7003787662)Gerasimos (7003787662)FilippatosMaggioni, Aldo P. (57203255222)Aldo P. (57203255222)Maggioni2025-06-122025-06-122017https://doi.org/10.1002/ejhf.890https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018783513&doi=10.1002%2fejhf.890&partnerID=40&md5=9eb16e816a7e0d5499f1a748764fc656https://remedy.med.bg.ac.rs/handle/123456789/6767Aims: To identify differences in clinical epidemiology, in-hospital management and 1-year outcomes among patients hospitalized for acute heart failure (AHF) and enrolled in the European Society of Cardiology Heart Failure Long-Term (ESC-HF-LT) Registry, stratified by clinical profile at admission. Methods and results: The ESC-HF-LT Registry is a prospective, observational study collecting hospitalization and 1-year follow-up data from 6629 AHF patients. Among AHF patients enrolled in the registry, 13.2% presented with pulmonary oedema (PO), 2.9% with cardiogenic shock (CS), 61.1% with decompensated heart failure (DHF), 4.8% with hypertensive heart failure (HT-HF), 3.5% with right heart failure (RHF) and 14.4% with AHF and associated acute coronary syndromes (ACS-HF). The 1-year mortality rate was 28.1% in PO, 54.0% in CS, 27.2% in DHF, 12.8% in HT-HF, 34.0% in RHF and 20.6% in ACS-HF patients. When patients were classified by systolic blood pressure (SBP) at initial presentation, 1-year mortality was 34.8% in patients with SBP <85 mmHg, 29.0% in those with SBP 85–110 mmHg, 21.2% in patients with SBP 110–140 mmHg and 17.4% in those with SBP >140 mmHg. These differences tended to diminish in the months post-discharge, and 1-year mortality for the patients who survived at least 6 months post-discharge did not vary significantly by either clinical profile or SBP classification. Conclusion: Rates of adverse outcomes in AHF remain high, and substantial differences have been found when patients were stratified by clinical profile or SBP. However, patients who survived at least 6 months post-discharge represent a more homogeneous group and their 1-year outcome is less influenced by clinical profile or SBP at admission. © 2017 The Authors. European Journal of Heart Failure © 2017 European Society of CardiologyAcute heart failureClinical profileOutcomes