Stojanovic, Borko (54390096600)Borko (54390096600)StojanovicBizic, Marta (23970012900)Marta (23970012900)BizicBencic, Marko (57194199573)Marko (57194199573)BencicDjordjevic, Miroslav L. (7102319341)Miroslav L. (7102319341)Djordjevic2025-06-122025-06-122023https://doi.org/10.3389/fendo.2023.1184948https://www.scopus.com/inward/record.uri?eid=2-s2.0-85162661896&doi=10.3389%2ffendo.2023.1184948&partnerID=40&md5=9a35ba788dbf30d4d549c300d56cdc99https://remedy.med.bg.ac.rs/handle/123456789/3053Purpose: This study aimed to evaluate a group of adult patients with non-urethral complications after hypospadias repair in childhood, their surgical treatment, and outcomes. Materials and methods: We analyzed 97 patients, mean age 22.5 years, who were treated in our center between January 2009 and December 2020, for non-urethral complications after previous hypospadias repair in childhood. Non-urethral complications were defined as glans deformity, residual curvature and trapped penis due to insufficient penile skin. A radical surgical approach was used to correct all deformities, in a one-stage or a two-stage procedure. A successful outcome was defined as a straight penis with good length, anatomically regular glans, and cosmetically acceptable appearance, without need for additional surgeries. Sexual function was evaluated using International Index of Erectile Function. Results: Mean follow-up was 75 months (ranged from 24 to 168 months). One-stage and two-stage repair were performed in 85.5% and 14.5% of cases, respectively. A higher success rate was noted after one-stage repair (94% compared to 86%). Complications included four cases of penile curvature with late onset, one case of glans dehiscence and partial skin necrosis. Erectile dysfunction was determined in 24% of patients. Discussion: Non-urethral complications may occur many years after primary hypospadias repair, with a strong impact on the quality of life. Treatment is individualized and usually involves a radical surgical approach to correct all associated deformities and to achieve successful cosmetic and psychosexual outcomes. Copyright © 2023 Stojanovic, Bizic, Bencic and Djordjevic.complicationshypospadiaspenile curvaturereconstructiontrapped penis