Popadic, Svetlana (24830928800)Svetlana (24830928800)PopadicTomanovic, Marija (58092757700)Marija (58092757700)TomanovicMinic, Snezana (35409907200)Snezana (35409907200)Minic2025-06-122025-06-122023https://doi.org/10.1111/ajd.13997https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147530005&doi=10.1111%2fajd.13997&partnerID=40&md5=937cd8d1cff9e42f04837a84b16f51a0https://remedy.med.bg.ac.rs/handle/123456789/2699Seborrheic keratosis is the most common slow-growing, benign epithelial tumour, usually appearing on sun-exposed areas. Treatment modalities for seborrheic keratosis may be uncomfortable and/or time-consuming. We present a case series of 12 patients with solitary seborrheic keratosis localized on the face treated with 0.005% calcipotriol ointment. The treatment lasted 3–8 months and resulted in complete regression of the lesions. Remission (follow-up period) lasted from 6 to 10 years. We conclude that topical calcipotriol may be a useful treatment option for seborrheic keratosis. © 2023 The Australasian College of Dermatologists.calcipotriolcomplete regressionseborrheic keratosistopical treatmentvitamin D3 analogue