Jovanovic, Ivan (7005436430)Ivan (7005436430)JovanovicCaro, Carlos (53163154300)Carlos (53163154300)CaroNeumann, Helmut (23100999100)Helmut (23100999100)NeumannLux, Anke (26534629900)Anke (26534629900)LuxKuester, Doerthe (8660179200)Doerthe (8660179200)KuesterFry, Lucia C. (7103263994)Lucia C. (7103263994)FryMalfertheiner, Peter (36048150200)Peter (36048150200)MalfertheinerMönkemüller, Klaus (7004857547)Klaus (7004857547)Mönkemüller2025-06-122025-06-122011https://doi.org/10.1016/j.cgh.2011.06.027https://www.scopus.com/inward/record.uri?eid=2-s2.0-80053132841&doi=10.1016%2fj.cgh.2011.06.027&partnerID=40&md5=fbc0c24d01cb3b16b1723057d9c5de5ehttps://remedy.med.bg.ac.rs/handle/123456789/9987Background & Aims: Although the "submucosal cushion" technique or injection-assisted polypectomy (IAP) is often used to resect colon polyps, little is known on the influence of this technique on histologic interpretation. We aimed to evaluate whether the use of a submucosal cushion improves the histologic and margin evaluation of colon polyps. Methods: Consecutive patients undergoing polypectomy with and without IAP were included. An experienced blinded gastrointestinal pathologist evaluated the specimens using standardized criteria. Results: One hundred eleven sessile colon adenomas were analyzed (IAP, n = 65, standard, n = 46). Two-thirds of polyps ranged in size from 10 to 20 mm; the average polyp size was 13.2 mm for IAP and 9.9 mm for standard snare polypectomy (P = .001). The cautery degree, cautery amount, and margin evaluability, did not differ substantially with regard to the resection technique. For polyps ≥10-20 mm, the overall architecture quality was better in polyps resected with standard technique as compared with IAP. Conclusions: The utilization of IAP did not result in a better margin evaluability of the resected polyp. Overall, IAP does not result in a better histologic polyp evaluability. © 2011 AGA Institute.Colon PolypHistologic EvaluationMucosectomyPolypectomySubmucosal Cushion