Janković, Slavenka M. (7101906308)Slavenka M. (7101906308)JankovićRadosavljević, Vladan R. (55889665400)Vladan R. (55889665400)RadosavljevićMarinković, Jelena M. (7004611210)Jelena M. (7004611210)Marinković2025-06-122025-06-121997https://doi.org/10.1023/A:1007304830553https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031057159&doi=10.1023%2fA%3a1007304830553&partnerID=40&md5=d6a3c6f8d4340b7bdc2cd7433797bf7ehttps://remedy.med.bg.ac.rs/handle/123456789/1649A case-control study of 100 newly diagnosed patients with Graves' disease and the same numbers of controls matched with respect to sex, age (± 2 years) and type of residence (rural-urban) was carried out. According to the matched analysis (McNemar's test and t-test) seventeen variables recognized as risk factors were included into the model of multivariate conditional logistic regression. The following factors were significantly associated with the occurrence of Graves' disease: change in time spent on work - much overtime work, second job, much less work than usual (RR = 6.62; CI = 2.08-21.01), lack of readiness of relatives and friends to help the subject (RR = 1.48; 95% CI = 1.14-1.93), increased arguments with spouse (RR = 14.12; 95% CI = 1.63-121.87), unemployment for at least one month (RR = 9.80; 95% CI = 1.13-85.02), and family history of Graves disease in the first degree of relation (RR = 7.20; 95% Cl = 0.85-60.70).case-control studyGraves' diseaserisk factors